(Q44526270)

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The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis.

scientific article published on 29 October 2012

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16 February 2020

The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis (English)

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16 February 2020

Enrique de Alava

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16 February 2020

Cinzia Lavarino

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Cinzia Lavarino

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16 February 2020

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Carla Casalà

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16 February 2020

Estel Gil-Guiñón

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16 February 2020

José Luis Ordóñez

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16 February 2020

Solange Miguel-Queralt

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16 February 2020

Eva Rodríguez

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16 February 2020

Patricia Galván

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16 February 2020

Francina Munell

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16 February 2020

Jaume Mora

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16 February 2020

Carmen de Torres

11

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16 February 2020

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29 October 2012

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16 February 2020

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16 February 2020

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16 February 2020

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16 February 2020

268-276

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16 February 2020

Recent advances in neuroblastoma

1 reference

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21 January 2018

Neuroblastoma: biological insights into a clinical enigma

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21 January 2018

Role of ploidy, chromosome 1p, and Schwann cells in the maturation of neuroblastoma.

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21 January 2018

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

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21 January 2018

The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report

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21 January 2018

Comprehensive analysis of tumoral DNA content reveals clonal ploidy heterogeneity as a marker with prognostic significance in locoregional neuroblastoma

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21 January 2018

Characteristics of stem cells from human neuroblastoma cell lines and in tumors

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International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group.

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21 January 2018

CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells

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21 January 2018

CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression

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21 January 2018

CD133 suppresses neuroblastoma cell differentiation via signal pathway modification

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21 January 2018

The calcium-sensing receptor and parathyroid hormone-related protein are expressed in differentiated, favorable neuroblastic tumors

1 reference

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21 January 2018

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid

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21 January 2018

The role of the calcium-sensing receptor in the development and progression of cancer

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21 January 2018

Extracellular calcium as a candidate mediator of prostate cancer skeletal metastasis

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21 January 2018

Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D.

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21 January 2018

Quantification of MYCN, DDX1, and NAG gene copy number in neuroblastoma using a real-time quantitative PCR assay

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21 January 2018

Optimal primer design using the novel primer design program: MSPprimer provides accurate methylation analysis of the ATM promoter.

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21 January 2018

Differential expression of genes mapping to recurrently abnormal chromosomal regions characterize neuroblastic tumours with distinct ploidy status

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21 January 2018

EMP3, a myelin-related gene located in the critical 19q13.3 region, is epigenetically silenced and exhibits features of a candidate tumor suppressor in glioma and neuroblastoma.

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21 January 2018

Nonparametric Estimation from Incomplete Observations

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21 January 2018

Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma

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21 January 2018

Association of epigenetic inactivation of RASSF1A with poor outcome in human neuroblastoma.

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21 January 2018

Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome

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21 January 2018

Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas.

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21 January 2018

Losses of chromosomes 1p and 3q are early genetic events in the development of sporadic pheochromocytomas

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21 January 2018

Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma

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Genome based cell population heterogeneity promotes tumorigenicity: the evolutionary mechanism of cancer

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A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

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21 January 2018

Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase

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21 January 2018

cDNA cloning and functional expression of a Ca2+-sensing receptor with truncated C-terminal tail from the Mozambique tilapia (Oreochromis mossambicus).

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High affinity interaction with filamin A protects against calcium-sensing receptor degradation.

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21 January 2018

DNA methylation screening identifies driver epigenetic events of cancer cell survival

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21 January 2018

The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

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10.1093/CARCIN/BGS338

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Europe PubMed Central

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16 February 2020

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16 February 2020

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