(Q37618297)

21 August 2017

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title

ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence (English)

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21 August 2017

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Sebastien Cagnol

1

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21 August 2017

Jean-Claude Chambard

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

16 October 2009

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21 August 2017

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21 August 2017

volume

277

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21 August 2017

issue

1

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21 August 2017

page(s)

2-21

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The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells

21 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An evaluation of the role of insulin-like growth factors (IGF) and of type-I IGF receptor signalling in hepatocarcinogenesis and in the resistance of hepatocarcinoma cells against drug-induced apoptosis

21 January 2018

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Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death

21 January 2018

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ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

21 January 2018

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PKC epsilon -mediated ERK1/2 activation involved in radiation-induced cell death in NIH3T3 cells

21 January 2018

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Regulation of p53 target gene expression by cisplatin-induced extracellular signal-regulated kinase

21 January 2018

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Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines.

21 January 2018

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Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells

21 January 2018

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Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells

21 January 2018

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Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation

21 January 2018

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Activation of ERK during DNA damage-induced apoptosis involves protein kinase Cdelta

21 January 2018

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Role of ERK activation in cisplatin-induced apoptosis in OK renal epithelial cells

21 January 2018

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Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance

21 January 2018

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A death-promoting role for extracellular signal-regulated kinase

21 January 2018

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Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway

21 January 2018

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Signalling responses linked to betulinic acid-induced apoptosis are antagonized by MEK inhibitor U0126 in adherent or 3D spheroid melanoma irrespective of p53 status

21 January 2018

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Unbalanced activation of ERK1/2 and MEK1/2 in apigenin-induced HeLa cell death

21 January 2018

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Cytochrome c release from oridonin-treated apoptotic A375-S2 cells is dependent on p53 and extracellular signal-regulated kinase activation

21 January 2018

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Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation

21 January 2018

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Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.

21 January 2018

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Oncogenic Ras sensitizes normal human cells to tumor necrosis factor-alpha-related apoptosis-inducing ligand-induced apoptosis

21 January 2018

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Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.

21 January 2018

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hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways.

21 January 2018

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LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors

21 January 2018

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A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis.

21 January 2018

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ERK and JNK mediate TNFalpha-induced p53 activation in apoptotic and autophagic L929 cell death

21 January 2018

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Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-alpha-induced cell death in MCF-7 cells

21 January 2018

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Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway

21 January 2018

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Erk-dependent cytosolic phospholipase A2 activity is induced by CD95 ligand cross-linking in the mouse derived Sertoli cell line TM4 and is required to trigger apoptosis in CD95 bearing cells

21 January 2018

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Constitutive activation of extracellular signal-regulated kinase predisposes diffuse large B-cell lymphoma cell lines to CD40-mediated cell death

21 January 2018

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CD40 mediated human cholangiocyte apoptosis requires JAK2 dependent activation of STAT3 in addition to activation of JNK1/2 and ERK1/2.

21 January 2018

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Involvement of activation of NADPH oxidase and extracellular signal-regulated kinase (ERK) in renal cell injury induced by zinc

21 January 2018

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Involvement of Raf-1/MEK/ERK1/2 signaling pathway in zinc-induced injury in rat renal cortical slices

21 January 2018

1 reference

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Mitogen-activated protein kinases contribute to reactive oxygen species-induced cell death in renal proximal tubule epithelial cells

21 January 2018

1 reference

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Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium

21 January 2018

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Activation of ERK1/2 pathway mediates oxidant-induced decreases in mitochondrial function in renal cells

21 January 2018

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Oxidative stress-induced apoptosis is mediated by ERK1/2 phosphorylation

21 January 2018

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Role of mitogen-activated protein kinases in hydrogen peroxide-induced cell death in osteoblastic cells

21 January 2018

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ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells

21 January 2018

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Extracellular signal-regulated kinase activation mediates mitochondrial dysfunction and necrosis induced by hydrogen peroxide in renal proximal tubular cells

21 January 2018

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Mitogen-activated protein kinases mediate peroxynitrite-induced cell death in human bronchial epithelial cells.

21 January 2018

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Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death

21 January 2018

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ERK activation increases nitroprusside induced apoptosis in human melanoma cells irrespective of p53 status: role of superoxide dismutases.

21 January 2018

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Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

21 January 2018

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MAPK regulate p53-dependent cell death induced by benzo[a]pyrene: involvement of p53 phosphorylation and acetylation

21 January 2018

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Arsenite-induced germline apoptosis through a MAPK-dependent, p53-independent pathway in Caenorhabditis elegans

21 January 2018

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Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens

21 January 2018

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Tamoxifen-induced rapid death of MCF-7 breast cancer cells is mediated via extracellularly signal-regulated kinase signaling and can be abrogated by estrogen

21 January 2018

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Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin

21 January 2018

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Involvement of MEK/ERK pathway in cephaloridine-induced injury in rat renal cortical slices

21 January 2018

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Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation

21 January 2018

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Inhibition of ligand-independent ERK1/2 activity in kidney proximal tubular cells deprived of soluble survival factors up-regulates Akt and prevents apoptosis.

21 January 2018

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Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells

21 January 2018

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Activation of extracellular signal-regulated kinase mediates apoptosis induced by uropathogenic Escherichia coli toxins via nitric oxide synthase: protective role of heme oxygenase-1.

21 January 2018

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The role of MAPK signal pathways during Francisella tularensis LVS infection-induced apoptosis in murine macrophages.

21 January 2018

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Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.

21 January 2018

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Extinction of rac1 and Cdc42Hs signalling defines a novel p53-dependent apoptotic pathway

21 January 2018

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Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt.

21 January 2018

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

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The involvement of MAPK signaling pathways in determining the cellular response to p53 activation: cell cycle arrest or apoptosis

21 January 2018

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Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK

21 January 2018

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H-Ras/mitogen-activated protein kinase pathway inhibits integrin-mediated adhesion and induces apoptosis in osteoblasts

21 January 2018

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Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix

21 January 2018

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Prolonged activation of ERK1,2 induces FADD-independent caspase 8 activation and cell death.

21 January 2018

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Vanishin is a novel ubiquitinylated death-effector domain protein that blocks ERK activation

21 January 2018

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Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain

21 January 2018

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Phosphorylation of PEA-15 switches its binding specificity from ERK/MAPK to FADD

21 January 2018

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Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin

21 January 2018

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ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

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A negative feedback signaling network underlies oncogene-induced senescence

21 January 2018

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

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Extracellular signal-regulated kinase 1/2-mediated phosphorylation of cytosolic phospholipase A2 is essential for human eosinophil adhesion to fibronectin.

21 January 2018

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cPLA2 is phosphorylated and activated by MAP kinase

21 January 2018

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ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage

21 January 2018

1 reference

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Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response

21 January 2018

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Oxidative neuronal injury. The dark side of ERK1/2.

21 January 2018

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Extracellular signal-regulated kinase as an inducer of non-apoptotic neuronal death

21 January 2018

1 reference

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Phosphoprotein enriched in astrocytes-15 is expressed in mouse testis and protects spermatocytes from apoptosis.

21 January 2018

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Fertilization blocks apoptosis of starfish eggs by inactivation of the MAP kinase pathway

21 January 2018

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Induction of apoptosis in starfish eggs requires spontaneous inactivation of MAPK (extracellular signal-regulated kinase) followed by activation of p38MAPK.

21 January 2018

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MAP kinases regulate unfertilized egg apoptosis and fertilization suppresses death via Ca2+ signaling

21 January 2018

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MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb

21 January 2018

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

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The cadmium-induced death of mesangial cells results in nephrotoxicity.

21 January 2018

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Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells

21 January 2018

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Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells

21 January 2018

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Inhibition of Akt signaling and enhanced ERK1/2 activity are involved in induction of macroautophagy by triterpenoid B-group soyasaponins in colon cancer cells

21 January 2018

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Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity

21 January 2018

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Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 l

21 January 2018

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PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival

21 January 2018

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Autophagy mediates the mitotic senescence transition

21 January 2018

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Cellular senescence in cancer and aging

21 January 2018

1 reference

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

1 reference

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Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

21 January 2018

1 reference

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Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling

21 January 2018

1 reference

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C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells

21 January 2018

1 reference

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

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Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

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Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor

21 January 2018

1 reference

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Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

21 January 2018

1 reference

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A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

21 January 2018

1 reference

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Dual role of MEK/ERK signaling in senescence and transformation of intestinal epithelial cells

21 January 2018

1 reference

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Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence

21 January 2018

1 reference

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Metabolic stabilization of MAP kinase phosphatase-2 in senescence of human fibroblasts.

21 January 2018

1 reference

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Modulation of replicative senescence of diploid human cells by nuclear ERK signaling

21 January 2018

1 reference

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Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

1 reference

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High frequency of BRAF mutations in nevi

21 January 2018

1 reference

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Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

21 January 2018

1 reference

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

1 reference

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Oxidative stress and apoptosis: impact on cancer therapy.

21 January 2018

1 reference

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Dopamine induces ERK activation in renal epithelial cells through H2O2 produced by monoamine oxidase

21 January 2018

1 reference

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Redox regulation of cell signalling

21 January 2018

1 reference

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Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

21 January 2018

1 reference

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Reversible oxidation of ERK-directed protein phosphatases drives oxidative toxicity in neurons

21 January 2018

1 reference

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Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival

21 January 2018

1 reference

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A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death

21 January 2018

1 reference

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ERK5 is involved in TCR-induced apoptosis through the modification of Nur77.

21 January 2018

1 reference

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Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis

21 January 2018

1 reference

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

21 January 2018

1 reference

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10.1111/J.1742-4658.2009.07366.X

21 January 2018

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DOI

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21 August 2017

1 reference