(Q41721937)

8 October 2017

title

The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicity (English)

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8 October 2017

3

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8 October 2017

6

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8 October 2017

Aoki M

1

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8 October 2017

Schetter C

series ordinal

2

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8 October 2017

Batista O

series ordinal

4

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8 October 2017

Chang HW

series ordinal

5

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8 October 2017

language of work or name

English

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publication date

1 March 2000

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Journal of Biological Chemistry

8 October 2017

published in

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8 October 2017

volume

275

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8 October 2017

issue

9

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8 October 2017

page(s)

6267-6275

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Structural and functional diversity of phosphoinositide 3-kinases.

8 October 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Structure and function of phosphoinositide 3-kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

21 January 2018

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Using structure to define the function of phosphoinositide 3-kinase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Phosphatidylinositol metabolism and polyoma-mediated transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Phosphatidylinositol kinase activity associates with viral p60src protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

New Procedure for DNA Transfection with Polycation and Dimethyl Sulfoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Formation of phosphatidylinositol 3-phosphate by isomerization from phosphatidylinositol 4-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Mechanism of activation and function of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

The akt kinase: molecular determinants of oncogenicity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

The role of PI 3-kinase in insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.9.6267

21 January 2018

Identifiers

DOI

10.1074/JBC.275.9.6267

1 reference

8 October 2017

1 reference