(Q38556727)

4 September 2017

1 reference

title

Phosphoinositide 3-kinases: a conserved family of signal transducers (English)

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phosphatidylinositol 3-kinase regulator activity

4 September 2017

main subject

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phosphatidylinositol 3-kinase complex, class IA

GO:0035014

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phosphatidylinositol 3-kinase activity

GO:0005943

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phosphatidylinositol 3-kinase complex, class III

GO:0035004

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phosphatidylinositol 3-kinase complex, class IB

GO:0035032

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phosphatidylinositol 3-kinase binding

GO:0005944

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Phosphatidylinositol 3-kinase 59F Dmel_CG5373

GO:0043548

1 reference

GOA release 2020-03-11

author name string

Vanhaesebroeck B

1

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4 September 2017

Leevers SJ

2

1 reference

4 September 2017

Panayotou G

3

1 reference

4 September 2017

Waterfield MD

4

1 reference

4 September 2017

publication date

1 July 1997

1 reference

4 September 2017

number of pages

6

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Trends in Biochemical Sciences

inferred from page(s)

published in

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4 September 2017

volume

22

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4 September 2017

issue

7

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4 September 2017

page(s)

267-272

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4 September 2017

cites work

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

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Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

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Structural and functional diversity of phosphoinositide 3-kinases.

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7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

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Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

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The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

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A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction

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An essential role for a protein and lipid kinase complex in secretory protein sorting

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Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

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Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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7 January 2021

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

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7 January 2021

When is a lipid kinase not a lipid kinase? When it is a protein kinase

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Akt signaling: linking membrane events to life and death decisions

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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Mechanism of activation of protein kinase B by insulin and IGF-1

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7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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7 January 2021

GSK3: a SHAGGY frog story

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p70 S6 kinase: an enigma with variations

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The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

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7 January 2021

Activation of PRK1 by phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. A comparison with protein kinase C isotypes

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7 January 2021

A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development

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7 January 2021

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

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7 January 2021

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

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7 January 2021

p60 is an adaptor for the Drosophila phosphoinositide 3-kinase, Dp110.

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7 January 2021

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7 January 2021

PH domains--a universal membrane adapter

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7 January 2021

10.1016/S0968-0004(97)01061-X

Identifiers

DOI

1 reference

4 September 2017

1 reference