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KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.
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PMC publication ID
4714561
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725010%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
title
KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II
(English)
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PMC publication ID
4714561
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725010%20AND%20SRC:MED&resulttype=core&format=json
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3 March 2020
author
Ryan P McNamara
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1
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4714561
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3 March 2020
Curtis W Bacon
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4
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4714561
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3 March 2020
author name string
Jonathan E Reeder
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2
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4714561
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3 March 2020
Elizabeth A McMillan
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3
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4714561
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3 March 2020
Jennifer L McCann
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5
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4714561
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3 March 2020
Iván D'Orso
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6
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4714561
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3 March 2020
publication date
24 December 2015
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3 March 2020
published in
Molecular Cell
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3 March 2020
volume
61
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4714561
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3 March 2020
issue
1
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4714561
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3 March 2020
page(s)
39-53
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3 March 2020
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Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186
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7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
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Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.
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RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation
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A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
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NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II.
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KAP1 controls endogenous retroviruses in embryonic stem cells
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A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal
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21 September 2018
Identifiers
DOI
10.1016/J.MOLCEL.2015.11.004
1 reference
stated in
Europe PubMed Central
PMC publication ID
4714561
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PMC publication ID
4714561
1 reference
stated in
Europe PubMed Central
PMC publication ID
4714561
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PubMed publication ID
26725010
1 reference
stated in
Europe PubMed Central
PMC publication ID
4714561
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725010%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
ResearchGate publication ID
288058660
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