(Q36213070)

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Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype

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24 February 2020

Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype (English)

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24 February 2020

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Grant W. Montgomery

8

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24 February 2020

Leesa F. Wockner

9

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24 February 2020

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V L J Whitehall

1

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24 February 2020

T D Dumenil

2

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24 February 2020

D M McKeone

3

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24 February 2020

C E Bond

4

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24 February 2020

M L Bettington

5

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24 February 2020

R L Buttenshaw

6

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24 February 2020

L Bowdler

7

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24 February 2020

B A Leggett

10

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24 February 2020

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1 November 2014

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24 February 2020

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24 February 2020

9

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24 February 2020

11

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24 February 2020

1454-1460

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24 February 2020

describes a project that uses

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Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/4622530

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Focus on genetic and epigenetic events of colorectal cancer pathogenesis: implications for molecular diagnosis

1 reference

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1 October 2017

CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer.

1 reference

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1 October 2017

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1 October 2017

Epigenetics and colorectal cancer pathogenesis

1 reference

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1 October 2017

Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.

1 reference

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1 October 2017

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1 reference

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1 October 2017

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

1 reference

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1 October 2017

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1 October 2017

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1 reference

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Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation.

1 reference

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1 October 2017

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1 October 2017

SWAN: Subset-quantile within array normalization for illumina infinium HumanMethylation450 BeadChips

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1 October 2017

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1 October 2017

Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients

1 reference

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1 October 2017

IDH mutation impairs histone demethylation and results in a block to cell differentiation

1 reference

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1 October 2017

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622530

1 October 2017

The CpG island methylator phenotype in colorectal cancer: progress and problems

1 reference

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1 October 2017

Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production

1 reference

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1 October 2017

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

1 reference

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1 October 2017

IDH1 and IDH2 mutations in pediatric acute leukemia

1 reference

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1 October 2017

Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP).

1 reference

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1 October 2017

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 reference

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1 October 2017

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

1 reference

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1 October 2017

Alcohol consumption and rectal tumor mutations and epigenetic changes

1 reference

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1 October 2017

Cigarette smoking and colorectal cancer risk by molecularly defined subtypes

1 reference

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1 October 2017

Role of the serrated pathway in colorectal cancer pathogenesis

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1 October 2017

Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes

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1 October 2017

Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor

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1 October 2017

The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status

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The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

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1 October 2017

IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group

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Three DNA methylation epigenotypes in human colorectal cancer

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

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Recurring mutations found by sequencing an acute myeloid leukemia genome

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IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

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1 October 2017

IDH1 and IDH2 mutations in gliomas

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1 October 2017

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

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1 October 2017

Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample

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1 October 2017

Analysis of the IDH1 codon 132 mutation in brain tumors

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1 October 2017

LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

1 reference

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1 October 2017

Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer.

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1 October 2017

Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample

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1 October 2017

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1 October 2017

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1 October 2017

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

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1 October 2017

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1 October 2017

CpG island methylator phenotype in colorectal cancer

1 reference

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1 October 2017

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

1 reference

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1 October 2017

IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.

1 reference

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29 June 2018

Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4622530

29 June 2018

Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer.

1 reference

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21 January 2018

Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

1 reference

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21 January 2018

IDH1/2 gene status defines the prognosis and molecular profiles in patients with grade III gliomas

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22 September 2018

The positive false discovery rate: a Bayesian interpretation and the q -value

1 reference

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21 January 2018

Hyperplastic Polyposis Syndrome Is Associated With Cigarette Smoking, Which May Be a Modifiable Risk Factor

1 reference

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21 January 2018

Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25496513

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25496513

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/15592294.2014.971624

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Europe PubMed Central

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24 February 2020

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24 February 2020

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Europe PubMed Central

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24 February 2020

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