(Q35743149)

10 August 2017

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title

Death receptors in chemotherapy and cancer (English)

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10 August 2017

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Klaus-Michael Debatin

series ordinal

1

object named as

Klaus-Michael Debatin

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author name string

Peter H Krammer

series ordinal

2

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10 August 2017

language of work or name

English

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publication date

1 April 2004

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10 August 2017

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10 August 2017

volume

23

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10 August 2017

issue

16

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10 August 2017

page(s)

2950-2966

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Expression and prognostic significance of survivin in de novo acute myeloid leukaemia

10 August 2017

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Can expression of apoptosis genes, bcl-2 and bax, predict survival and responsiveness to chemotherapy in node-negative breast cancer patients?

21 January 2018

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Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

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A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma.

21 January 2018

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The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia.

21 January 2018

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p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma

21 January 2018

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Apoptotic DNA fragmentation

21 January 2018

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The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

21 January 2018

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Bcl-2 and bcl-xL antisense oligonucleotides induce apoptosis in melanoma cells of different clinical stages

21 January 2018

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Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma

21 January 2018

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p53 and bcl-2 expression in high-grade B-cell lymphomas: correlation with survival time

21 January 2018

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Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy

21 January 2018

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Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions

21 January 2018

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Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).

21 January 2018

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Countering the 'counterattack' hypothesis.

21 January 2018

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The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

21 January 2018

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Cross-talk in cell death signaling

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IAP proteins: blocking the road to death's door

21 January 2018

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Bcl-2 and apoptosis in chronic lymphocytic leukemia

21 January 2018

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Analysis of the p53/BAX pathway in colorectal cancer: low BAX is a negative prognostic factor in patients with resected liver metastases

21 January 2018

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Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

21 January 2018

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21 January 2018

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21 January 2018

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Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis

21 January 2018

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The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

21 January 2018

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Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

21 January 2018

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Follicular large-cell lymphoma treated with intensive chemotherapy: an analysis of 89 cases included in the LNH87 trial and comparison with the outcome of diffuse large B-cell lymphoma. Groupe d'Etude des Lymphomes de l'Adulte.

21 January 2018

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Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence

21 January 2018

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Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

21 January 2018

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7 January 2021

Validating survivin as a cancer therapeutic target

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7 January 2021

Survivin and apoptosis control

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7 January 2021

Death receptors: signaling and modulation

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7 January 2021

Bcl-2, cell cycle regulatory proteins and corticosensitivity in childhood acute lymphoblastic leukaemia

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7 January 2021

Altered methylation patterns in cancer cell genomes: cause or consequence?

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7 January 2021

CD95 ligand-expressing tumors are rejected in anti-tumor TCR transgenic perforin knockout mice

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7 January 2021

Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL

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7 January 2021

A role for CD95 ligand in preventing graft rejection

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7 January 2021

Expression of apoptosis-controlling proteins in acute leukemia cells

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7 January 2021

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

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7 January 2021

Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4

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7 January 2021

Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma

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7 January 2021

XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage

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7 January 2021

Signal transduction by the JNK group of MAP kinases

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7 January 2021

Chemotherapy: targeting the mitochondrial cell death pathway

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7 January 2021

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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7 January 2021

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

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7 January 2021

Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML).

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7 January 2021

Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.

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7 January 2021

Does cancer therapy trigger cell suicide?

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7 January 2021

Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

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7 January 2021

IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway.

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7 January 2021

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

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7 January 2021

Chemosensitivity of solid tumor cellsin vitro is related to activation of the CD95 system

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7 January 2021

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

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7 January 2021

Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells

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7 January 2021

BAX and p16INK4A are independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancer

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7 January 2021

Death ligand/receptor-independent caspase activation mediates drug-induced cytotoxic cell death in human malignant glioma cells

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7 January 2021

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

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7 January 2021

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

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7 January 2021

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

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7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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7 January 2021

The biochemistry of apoptosis

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7 January 2021

Cellular stress response and apoptosis in cancer therapy.

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7 January 2021

XIAP, the guardian angel

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7 January 2021

Anticancer therapy targeting the apoptotic pathway

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7 January 2021

Death and anti-death: tumour resistance to apoptosis

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7 January 2021

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

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7 January 2021

Noncaspase proteases in apoptosis

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7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

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7 January 2021

Discrepant expression of membrane and soluble isoforms of Fas (CD95/APO-1) in adult T-cell leukaemia: soluble Fas isoform is an independent risk factor for prognosis

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7 January 2021

Immune response and myoblasts that express Fas ligand

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7 January 2021

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

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7 January 2021

Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy

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7 January 2021

Alterations in the apoptotic machinery and their potential role in anticancer drug resistance

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7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

High Bad and Bax mRNA expression correlate with negative outcome in acute myeloid leukemia (AML).

1 reference

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7 January 2021

CD95's deadly mission in the immune system

1 reference

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7 January 2021

CD95 antigen mutations in hematopoietic malignancies

1 reference

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7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

1 reference

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7 January 2021

Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

High bcl-2 expression in acute myeloid leukemia cells correlates with CD34 positivity and complete remission rate.

1 reference

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7 January 2021

Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar

1 reference

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7 January 2021

Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma

1 reference

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7 January 2021

Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Fas/Fas ligand interaction contributes to UV-induced apoptosis in human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins

1 reference

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7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

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7 January 2021

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

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7 January 2021

p53 status and the efficacy of cancer therapy in vivo

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

1 reference

7 January 2021

Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia

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7 January 2021

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

1 reference

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7 January 2021

STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.

1 reference

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7 January 2021

Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs.

1 reference

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7 January 2021

Expression of Fas antigen in acute myeloid leukaemia is associated with therapeutic response to chemotherapy

1 reference

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7 January 2021

Predictive value of Bcl-2 and Bax protein expression for chemotherapeutic effect in gastric cancer. A pilot study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

High bax expression is a good prognostic indicator in acute myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

The receptor for the cytotoxic ligand TRAIL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Inactivating mutations of KILLER/DR5 gene in gastric cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Inactivating mutations of the caspase-10 gene in gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Defying death after DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

In vivo patterns of Bcl-2 family protein expression in breast carcinomas in relation to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Prognostic implications of BAX and TGFBRII mutations in colon cancers with microsatellite instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Apoptosis: implications of basic research for clinical oncology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Alterations of Fas-pathway genes associated with nodal metastasis in non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Apoptosis induction in peripheral leukemia cells by remission induction treatment in vivo: selective depletion and apoptosis in a CD34+ subpopulation of leukemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Inhibition of fas death signals by FLIPs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

The prognostic relevance of apoptosis-related proteins in classical Hodgkin's lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation stage, and cytogenetics.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Constitutive expression levels of CD95 and Bcl-2 as well as CD95 function and spontaneous apoptosis in vitro do not predict the response to induction chemotherapy and relapse rate in childhood acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207558

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207558

1 reference

10 August 2017

1 reference