(Q35033286)

5 August 2017

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title

Neurological disease: UPS stops delivering! (English)

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5 August 2017

Richard J Miller

1

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5 August 2017

Scott M Wilson

series ordinal

2

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5 August 2017

publication date

1 January 2003

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Trends in Pharmacological Sciences

5 August 2017

published in

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5 August 2017

volume

24

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5 August 2017

issue

1

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5 August 2017

page(s)

18-23

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

5 August 2017

1 reference

7 January 2021

Ubiquitin--more than just a signal for protein degradation.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Aggregates in neurodegenerative disease: crowds and power?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Ubiquitin, cellular inclusions and their role in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Impairment of the ubiquitin-proteasome system by protein aggregation

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Deadly encounter: ubiquitin meets apoptosis

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Impaired proteasome function in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Expanding our understanding of polyglutamine diseases through mouse models

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Glutamine repeats and neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

The selective vulnerability of striatopallidal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Identification of genes that modify ataxin-1-induced neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Parkin and the molecular pathways of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Induction of alpha-synuclein aggregation by intracellular nitrative insult.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Failure of the ubiquitin-proteasome system in Parkinson's disease

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

The ubiquitin pathway in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

A polymorphic variation of serine to tyrosine at codon 18 in the ubiquitin C-terminal hydrolase-L1 gene is associated with a reduced risk of sporadic Parkinson's disease in a Japanese population

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia

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https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Calcium channels prove to be a real headache

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Ubiquitination-dependent mechanisms regulate synaptic growth and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Fat facets does a Highwire act at the synapse.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

+1 Proteins and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2900011-1

7 January 2021

10.1016/S0165-6147(02)00011-1

Identifiers

DOI

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5 August 2017

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