(Q33963199)

30 July 2017

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title

EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications (English)

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30 July 2017

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Daniel B Costa

3

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author name string

Hiroyuki Yasuda

series ordinal

1

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30 July 2017

Susumu Kobayashi

series ordinal

2

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30 July 2017

publication date

19 July 2011

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Lancet Oncology Commission

30 July 2017

published in

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30 July 2017

volume

13

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30 July 2017

issue

1

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30 July 2017

page(s)

e23-31

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30 July 2017

cites work

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7 January 2021

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7 January 2021

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7 January 2021

Prospective Validation for Prediction of Gefitinib Sensitivity by Epidermal Growth Factor Receptor Gene Mutation in Patients with Non-Small Cell Lung Cancer

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7 January 2021

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7 January 2021

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7 January 2021

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

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7 January 2021

Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer

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7 January 2021

Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer

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7 January 2021

Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response

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7 January 2021

Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants

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7 January 2021

Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors

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7 January 2021

Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing

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7 January 2021

Epidermal growth factor receptor mutations in lung cancer

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7 January 2021

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7 January 2021

Structure and clinical relevance of the epidermal growth factor receptor in human cancer

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7 January 2021

Structural and mechanistic underpinnings of the differential drug sensitivity of EGFR mutations in non-small cell lung cancer

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7 January 2021

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

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7 January 2021

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

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7 January 2021

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

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7 January 2021

Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib

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7 January 2021

Kinetic analysis of epidermal growth factor receptor somatic mutant proteins shows increased sensitivity to the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib

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7 January 2021

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7 January 2021

BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations

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7 January 2021

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7 January 2021

Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas

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7 January 2021

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7 January 2021

Somatic mutations of the tyrosine kinase domain of epidermal growth factor receptor and tyrosine kinase inhibitor response to TKIs in non-small cell lung cancer: an analytical database

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7 January 2021

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7 January 2021

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

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7 January 2021

High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan

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7 January 2021

Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib

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7 January 2021

Neratinib, an irreversible pan-ErbB receptor tyrosine kinase inhibitor: results of a phase II trial in patients with advanced non-small-cell lung cancer

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7 January 2021

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7 January 2021

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7 January 2021

Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials

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7 January 2021

EGFR exon 20 insertion mutation in Japanese lung cancer.

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7 January 2021

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials

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7 January 2021

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7 January 2021

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7 January 2021

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

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7 January 2021

PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib

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7 January 2021

BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

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7 January 2021

An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.

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7 January 2021

Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance

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7 January 2021

Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition.

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7 January 2021

HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy

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7 January 2021

Prospective Study of Gefitinib in Epidermal Growth Factor Receptor Fluorescence In Situ Hybridization–Positive/Phospho-Akt–Positive or Never Smoker Patients With Advanced Non–Small-Cell Lung Cancer: The ONCOBELL Trial

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7 January 2021

Erlotinib in lung cancer - molecular and clinical predictors of outcome

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7 January 2021

Activity of IPI-504, a Novel Heat-Shock Protein 90 Inhibitor, in Patients With Molecularly Defined Non–Small-Cell Lung Cancer

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7 January 2021

Non–Small Cell Lung Cancer

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7 January 2021

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

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7 January 2021

10.1016/S1470-2045(11)70129-2

Identifiers

DOI

1 reference

release_x3fr6oc5rngz5i7yhqagymg35a

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x3fr6oc5rngz5i7yhqagymg35a

24 November 2022

mapped directly with Wikidata item

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