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To cycle or not to cycle: a critical decision in cancer.
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Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
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8 December 2019
review article
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Europe PubMed Central
title
To cycle or not to cycle: a critical decision in cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author
Marcos Malumbres
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
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8 December 2019
author name string
Barbacid M
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
language of work or name
English
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publication date
1 December 2001
1 reference
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Europe PubMed Central
PubMed publication ID
11902577
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retrieved
8 December 2019
published in
Nature Reviews Cancer
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
222-231
1 reference
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Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
cites work
Animal cell cycles and their control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Checkpoints: controls that ensure the order of cell cycle events
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin-dependent kinases: engines, clocks, and microprocessors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of G1 kinase activity for cdk6, a novel cyclin D partner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic stimulation recruits cyclin-dependent kinase in the cell cycle start in rat fibroblast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin-dependent kinase 7: at the cross-roads of transcription, DNA repair and cell cycle control?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin D1 provides a link between development and oncogenesis in the retina and breast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rb/E2F pathway: expanding roles and emerging paradigms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma protein partners
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acetylation control of the retinoblastoma tumour-suppressor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of pRB dephosphorylation in cell cycle regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for cyclin-dependent kinases in cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New functional activities for the p21 family of CDK inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of Cyclin D1 Deficiency by Knockin Cyclin E
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin E-CDK2 is a regulator of p27Kip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the F-box protein Skp2 in lymphomagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Skp2 is oncogenic and overexpressed in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of an Rb mutation in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene family: cousins with overlapping interests
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p107 is a suppressor of retinoblastoma development in pRb-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The murine gene p27Kip1 is haplo-insufficient for tumour suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Invasive melanoma in Cdk4-targeted mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemical inhibitors of cyclin-dependent kinases: insights into design from X-ray crystallographic studies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small molecule inhibitors of dual specificity protein phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initial sequencing and analysis of the human genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibition and cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small-molecule inhibitors of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preclinical and clinical development of cyclin-dependent kinase modulators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cell cycle and drug discovery: the promise and the hope
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Properties and potential-applications of chemical inhibitors of cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Past and future of the mitotic spindle as an oncology target
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microtubule-stabilizing agents: a growing class of important anticancer drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An encore for ribosome biogenesis in the control of cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TOR, a central controller of cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TOR kinases link nutrient sensing to cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F35106065
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Restriction Point for Control of Normal Animal Cell Proliferation
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7 January 2021
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The restriction point and control of cell proliferation
1 reference
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reference URL
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7 January 2021
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Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
1 reference
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reference URL
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7 January 2021
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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2F35106065
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7 January 2021
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Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression
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reference URL
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7 January 2021
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The Drosophila cyclin D-Cdk4 complex promotes cellular growth
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reference URL
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7 January 2021
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Specific protection against breast cancers by cyclin D1 ablation
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reference URL
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7 January 2021
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Waiting for anaphase: Mad2 and the spindle assembly checkpoint
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7 January 2021
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Mitotic kinases as regulators of cell division and its checkpoints
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reference URL
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7 January 2021
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Mutations of mitotic checkpoint genes in human cancers
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7 January 2021
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MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
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reference URL
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7 January 2021
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Molecular analyses of the mitotic checkpoint components hsMAD2, hBUB1 and hBUB3 in human cancer
1 reference
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reference URL
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7 January 2021
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Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase
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7 January 2021
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Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines
1 reference
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reference URL
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7 January 2021
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Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis
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reference URL
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7 January 2021
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Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
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reference URL
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7 January 2021
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Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
1 reference
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reference URL
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7 January 2021
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Inhibition of cyclin-dependent kinases by purine analogues
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reference URL
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7 January 2021
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Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine
1 reference
stated in
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reference URL
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retrieved
7 January 2021
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Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles
1 reference
stated in
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reference URL
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retrieved
7 January 2021
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Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.
1 reference
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reference URL
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7 January 2021
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Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6.
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product
1 reference
stated in
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reference URL
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7 January 2021
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Identifiers
DOI
10.1038/35106065
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Dimensions Publication ID
1029289076
0 references
PubMed publication ID
11902577
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11902577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11902577%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
ResearchGate publication ID
11460612
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