(Q33898956)

29 July 2017

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title

Adapter proteins in lymphocyte antigen-receptor signaling (English)

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29 July 2017

Myung PS

1

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29 July 2017

Boerthe NJ

series ordinal

2

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29 July 2017

Koretzky GA

series ordinal

3

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29 July 2017

publication date

1 June 2000

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Current Opinion in Immunology

29 July 2017

published in

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29 July 2017

volume

12

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29 July 2017

issue

3

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29 July 2017

page(s)

256-266

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Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

29 July 2017

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7 January 2021

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

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Signaling through scaffold, anchoring, and adaptor proteins

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Complex complexes: signaling at the TCR.

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7 January 2021

Adaptor proteins in lymphocyte antigen-receptor signaling

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7 January 2021

SH2/SH3 signaling proteins

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7 January 2021

PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine

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Characterization of a novel protein-binding module--the WW domain

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Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

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7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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7 January 2021

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

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7 January 2021

Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT

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7 January 2021

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

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7 January 2021

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

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7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

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7 January 2021

Essential role of LAT in T cell development

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7 January 2021

Localization of LAT in glycolipid-enriched microdomains is required for T cell activation

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7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

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7 January 2021

Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases

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7 January 2021

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

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7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

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7 January 2021

SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity

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7 January 2021

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

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7 January 2021

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

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7 January 2021

Interaction of SLP adaptors with the SH2 domain of Tec family kinases

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7 January 2021

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

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7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

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7 January 2021

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

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7 January 2021

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

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7 January 2021

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

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7 January 2021

Novel isoform of lymphoid adaptor FYN-T-binding protein (FYB-130) interacts with SLP-76 and up-regulates interleukin 2 production

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7 January 2021

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

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7 January 2021

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

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7 January 2021

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

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7 January 2021

Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activation

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7 January 2021

BLNK: a central linker protein in B cell activation

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7 January 2021

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

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7 January 2021

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

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7 January 2021

Requirement for B cell linker protein (BLNK) in B cell development

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7 January 2021

Defective B cell development and function in Btk-deficient mice

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7 January 2021

An essential role for BLNK in human B cell development

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7 January 2021

Role of Bruton's tyrosine kinase in immunodeficiency

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7 January 2021

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

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7 January 2021

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

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7 January 2021

Clnk, a novel SLP-76-related adaptor molecule expressed in cytokine-stimulated hemopoietic cells

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7 January 2021

NK cytokine secretion and cytotoxicity occur independently of the SLP-76 adaptor protein

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7 January 2021

Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

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7 January 2021

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

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7 January 2021

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

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7 January 2021

Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation

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7 January 2021

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

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7 January 2021

The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase

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7 January 2021

Oct-1 protein promotes functional transcription complex assembly on the mouse mammary tumor virus promoter

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7 January 2021

Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl

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7 January 2021

B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins

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7 January 2021

Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G

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7 January 2021

Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation.

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7 January 2021

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

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7 January 2021

The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells

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7 January 2021

Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function

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7 January 2021

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

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7 January 2021

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

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7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

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7 January 2021

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

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7 January 2021

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

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7 January 2021

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha

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7 January 2021

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

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7 January 2021

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

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7 January 2021

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

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7 January 2021

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

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7 January 2021

SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation

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7 January 2021

A novel receptor involved in T-cell activation

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7 January 2021

Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes

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7 January 2021

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

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7 January 2021

10.1016/S0952-7915(00)00085-6

Identifiers

DOI

1 reference

29 July 2017

1 reference