(Q41113361)

26 September 2017

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title

Complex complexes: signaling at the TCR. (English)

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26 September 2017

Wange RL

1

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26 September 2017

Samelson LE

series ordinal

2

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26 September 2017

language of work or name

English

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publication date

1 September 1996

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26 September 2017

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26 September 2017

volume

5

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26 September 2017

issue

3

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26 September 2017

page(s)

197-205

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Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

26 September 2017

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Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

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T cell antigen receptor signal transduction pathways

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Cell-surface-expressed T-cell antigen-receptor zeta chain is associated with the cytoskeleton

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ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

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Syk tyrosine kinase required for mouse viability and B-cell development

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Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

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Signalling by receptor tyrosine kinases

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Syk Mutation in Jurkat E6-derived Clones Results in Lack of p72syk Expression

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Blocked Ras activation in anergic CD4+ T cells

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Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

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The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

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Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

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Signal transduction in T lymphocytes using a conditional allele of Sos

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Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells

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Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain

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ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity

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7 January 2021

Purification and characterization of human ZAP-70 protein-tyrosine kinase from a baculovirus expression system

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7 January 2021

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

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Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation

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7 January 2021

The tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cells

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Tyrosine phosphorylation of α tubulin in human T lymphocytes

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Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

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Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

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7 January 2021

Activation-modulated association of 14-3-3 proteins with Cbl in T cells

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7 January 2021

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

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7 January 2021

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

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7 January 2021

Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells

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7 January 2021

Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production

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Essential role for ZAP-70 in both positive and negative selection of thymocytes

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7 January 2021

Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins

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7 January 2021

A comparison of the interaction of Shc and the tyrosine kinase ZAP-70 with the T cell antigen receptor zeta chain tyrosine-based activation motif

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7 January 2021

The protein interactions of the immunoglobulin receptor family tyrosine-based activation motifs present in the T cell receptor zeta subunits and the CD3 gamma, delta and epsilon chains

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7 January 2021

Protein modules and signalling networks

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7 January 2021

Regulation of lymphocyte function by protein phosphorylation

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7 January 2021

Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosine

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7 January 2021

Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling

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7 January 2021

Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling

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7 January 2021

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

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7 January 2021

Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G

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7 January 2021

Tyrosine-phosphorylated T cell receptor ζ chain associates with the actin cytoskeleton upon Activation of mature T lymphocytes

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7 January 2021

Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE.

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7 January 2021

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

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7 January 2021

Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex

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7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

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7 January 2021

Signal transduction by receptors with tyrosine kinase activity

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7 January 2021

Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) zeta subunit: regulation of TCR-associated protein tyrosine kinase activity by TCR zeta.

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7 January 2021

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

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7 January 2021

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

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7 January 2021

Activating and Inhibitory Mutations in Adjacent Tyrosines in the Kinase Domain of ZAP-70

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7 January 2021

F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling

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7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

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7 January 2021

Signal transduction by lymphocyte antigen receptors

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7 January 2021

TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck

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7 January 2021

A functional T-cell receptor signaling pathway is required for p95vav activity

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7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

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7 January 2021

10.1016/S1074-7613(00)80315-5

Identifiers

DOI

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26 September 2017

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