(Q33866655)

29 July 2017

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title

The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance (English)

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29 July 2017

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M W Mayo

1

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29 July 2017

A S Baldwin

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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Biochimica et Biophysica Acta

29 July 2017

published in

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29 July 2017

volume

1470

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29 July 2017

issue

2

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29 July 2017

page(s)

M55-62

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The NF-kappa B and I kappa B proteins: new discoveries and insights

29 July 2017

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7 January 2021

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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation

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The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta

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Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

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NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

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Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

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7 January 2021

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

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7 January 2021

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

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A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation

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Expression of dominant negative Jun inhibits elevated AP-1 and NF-kappaB transactivation and suppresses anchorage independent growth of HPV immortalized human keratinocytes

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7 January 2021

Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways

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Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade

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Ras signalling and apoptosis

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Induction of NF-kappaB by the Akt/PKB kinase

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7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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7 January 2021

Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation

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7 January 2021

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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7 January 2021

TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha

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7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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7 January 2021

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

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7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

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7 January 2021

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7 January 2021

Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

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7 January 2021

Transcriptional cross talk between NF-kappaB and p53.

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7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

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7 January 2021

Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IkappaBalpha overexpression

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7 January 2021

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

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7 January 2021

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

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7 January 2021

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

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7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

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7 January 2021

The c-Jun-induced transformation process involves complex regulation of tenascin-C expression

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7 January 2021

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

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7 January 2021

Role of nitric oxide in tumor progression: lessons from experimental tumors

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7 January 2021

Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer

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7 January 2021

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7 January 2021

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7 January 2021

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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7 January 2021

Sulindac inhibits activation of the NF-kappaB pathway

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7 January 2021

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

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7 January 2021

Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

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7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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7 January 2021

Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas.

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7 January 2021

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

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7 January 2021

NF- kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF- kappa B

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7 January 2021

10.1016/S0304-419X(00)00002-0

Identifiers

DOI

1 reference

29 July 2017

1 reference