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Ras signalling and apoptosis
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Ras signalling and apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author
Julian Downward
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
publication date
1 February 1998
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
published in
Current Opinion in Genetics & Development
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
volume
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
page(s)
49-54
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
cites work
Cell cycle: routine role for Ras.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Function and regulation of ras.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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inferred from DOI database lookup
Signal transduction. How receptors turn Ras on.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras effectors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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inferred from DOI database lookup
PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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Evidence for a Ras/Ral signaling cascade
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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Complexes of p21RAS with JUN N-terminal kinase and JUN proteins
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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Loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signaling in tumor necrosis factor-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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inferred from DOI database lookup
Cooperating oncogenes converge to regulate cyclin/cdk complexes.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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inferred from DOI database lookup
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle arrest versus cell death in cancer therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras activation leads to cell proliferation or apoptotic cell death upon interleukin-2 stimulation or lymphokine deprivation, respectively
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinase suppressor of Ras is ceramide-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
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inferred from DOI database lookup
KSR: a novel player in the RAS pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas-induced apoptosis of T cells occurs independently of ceramide generation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of epithelial cell-matrix interactions induces apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activated H-ras rescues E1A-induced apoptosis and cooperates with E1A to overcome p53-dependent growth arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Susceptibility to apoptosis is differentially regulated by c-myc and mutated Ha-ras oncogenes and is associated with endonuclease availability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 targets the protein kinase Raf-1 to mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Endothelial apoptosis in Braf-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 does not require Raf kinase activity for its death-protective function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980061-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-437X(98)80061-0
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
PubMed publication ID
9529605
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9529605
retrieved
4 August 2017
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