(Q30845708)

27 June 2017

title

Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase (English)

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27 June 2017

Chan DW

1

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27 June 2017

Son SC

2

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27 June 2017

Block W

3

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27 June 2017

Ye R

4

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27 June 2017

Khanna KK

5

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27 June 2017

Wold MS

6

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27 June 2017

Douglas P

7

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27 June 2017

Goodarzi AA

8

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27 June 2017

Pelley J

9

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27 June 2017

Taya Y

10

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27 June 2017

Lavin MF

11

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27 June 2017

Lees-Miller SP

12

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27 June 2017

language of work or name

English

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publication date

1 March 2000

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Journal of Biological Chemistry

27 June 2017

published in

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27 June 2017

volume

275

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27 June 2017

issue

11

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27 June 2017

page(s)

7803-7810

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The genetic defect in ataxia-telangiectasia

27 June 2017

cites work

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The role of ATM in DNA damage responses and cancer

21 January 2018

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

21 January 2018

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21 January 2018

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The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

21 January 2018

1 reference

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Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

21 January 2018

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DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

21 January 2018

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Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

21 January 2018

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Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

21 January 2018

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

21 January 2018

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

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Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

21 January 2018

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Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation

21 January 2018

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Recombinant ATM protein complements the cellular A-T phenotype

21 January 2018

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Cloning and expression of the ataxia-telangiectasia gene in baculovirus

21 January 2018

1 reference

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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

21 January 2018

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ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

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DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

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The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

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Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

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Lack of correlation between ATM protein expression and tumour cell radiosensitivity

21 January 2018

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Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

1 reference

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Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

21 January 2018

1 reference

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DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45

21 January 2018

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Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells

21 January 2018

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Mapping of amino acid residues in the p34 subunit of human single-stranded DNA-binding protein phosphorylated by DNA-dependent protein kinase and Cdc2 kinase in vitro

21 January 2018

1 reference

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The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast

21 January 2018

1 reference

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Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

21 January 2018

1 reference

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RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

Signaling to p53: breaking the MDM2-p53 circuit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.11.7803

21 January 2018

Identifiers

DOI

10.1074/JBC.275.11.7803

1 reference

27 June 2017

1 reference