(Q35640429)

9 August 2017

title

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM. (English)

1 reference

9 August 2017

G C Smith

1

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9 August 2017

R B Cary

2

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9 August 2017

N D Lakin

3

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9 August 2017

B C Hann

4

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9 August 2017

S H Teo

5

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9 August 2017

D J Chen

6

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9 August 2017

S P Jackson

7

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9 August 2017

language of work or name

English

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publication date

1 September 1999

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9 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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9 August 2017

volume

96

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9 August 2017

issue

20

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9 August 2017

page(s)

11134-11139

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The DNA-dependent protein kinase

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

ATM associates with and phosphorylates p53: mapping the region of interaction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

ATM: from gene to function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Enhanced phosphorylation of p53 by ATM in response to DNA damage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

DNA damage induces phosphorylation of the amino terminus of p53

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

The genetic defect in ataxia-telangiectasia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

DNA looping by Ku and the DNA-dependent protein kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Analysis of the ATM protein in wild-type and ataxia telangiectasia cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

DNA damage detection by DNA dependent protein kinase and related enzymes.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Regulation of the specific DNA binding function of p53

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Cleavage and inactivation of ATM during apoptosis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Cryo-EM imaging of the catalytic subunit of the DNA-dependent protein kinase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Signalling through the lipid products of phosphoinositide-3-OH kinase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17999

Scanning force microscopy of nucleic acids and nucleoprotein assemblies

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.20.11134

DNA end-joining: from yeast to man

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/10500142

12 December 2020

Competitive and noncompetitive inhibition of the DNA-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10500142

12 December 2020

Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/10500142

12 December 2020

The product of the ATM gene is a 370-kDa nuclear phosphoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10500142

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.20.11134

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference