(Q28116305)

English

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

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scholarly article

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PubMed publication ID

4 January 2017

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription (English)

1 reference

PubMed publication ID

4 January 2017

0 references

phosphorylation

0 references

Cyclin dependent kinase 9

1 reference

GOA release 2020-03-11

transcription initiation from RNA polymerase II promoter

1 reference

GOA release 2020-03-11

0 references

author name string

M. Zhou

1

1 reference

PubMed publication ID

4 January 2017

M. A. Halanski

2

1 reference

PubMed publication ID

4 January 2017

M. F. Radonovich

3

1 reference

PubMed publication ID

4 January 2017

F. Kashanchi

4

1 reference

PubMed publication ID

4 January 2017

J. Peng

5

1 reference

PubMed publication ID

4 January 2017

D. H. Price

6

1 reference

PubMed publication ID

4 January 2017

J. N. Brady

7

1 reference

PubMed publication ID

4 January 2017

language of work or name

0 references

publication date

1 July 2000

1 reference

PubMed publication ID

4 January 2017

Molecular and Cellular Biology

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PubMed publication ID

4 January 2017

20

1 reference

PubMed publication ID

4 January 2017

14

1 reference

PubMed publication ID

4 January 2017

5077–5086

1 reference

PubMed publication ID

4 January 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC85957/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Cdk-activating kinase complex is a component of human transcription factor TFIIH

1 reference

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1 reference

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Identification of multiple cyclin subunits of human P-TEFb

1 reference

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20 March 2017

Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH

1 reference

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20 March 2017

Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

1 reference

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20 March 2017

A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription

1 reference

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20 March 2017

Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II

1 reference

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Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)

1 reference

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Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

1 reference

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20 March 2017

The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function

1 reference

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20 March 2017

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1 reference

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20 March 2017

Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast

1 reference

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20 March 2017

The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex

1 reference

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20 March 2017

The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD.

1 reference

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20 March 2017

Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases

1 reference

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20 March 2017

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae

1 reference

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20 March 2017

The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae

1 reference

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20 March 2017

KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity

1 reference

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20 March 2017

Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast

1 reference

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20 March 2017

Tat-associated kinase (P-TEFb): a component of transcription preinitiation and elongation complexes

1 reference

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20 March 2017

NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription

1 reference

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20 March 2017

Transcriptional control: Tat cofactors and transcriptional elongation

1 reference

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20 March 2017

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

1 reference

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20 March 2017

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

1 reference

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20 March 2017

The general transcription factors of RNA polymerase II

1 reference

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20 March 2017

Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain

1 reference

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20 March 2017

Requirements for RNA polymerase II carboxyl-terminal domain for activated transcription of human retroviruses human T-cell lymphotropic virus I and HIV-1

1 reference

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20 March 2017

Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II

1 reference

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20 March 2017

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

20 March 2017

Association of Cdk-activating kinase subunits with transcription factor TFIIH

1 reference

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20 March 2017

Recycling of the general transcription factors during RNA polymerase II transcription

1 reference

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20 March 2017

Principles of CDK regulation

1 reference

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7 April 2017

Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

1 reference

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7 April 2017

Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase

1 reference

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7 April 2017

Reversible phosphorylation of the C-terminal domain of RNA polymerase II

1 reference

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7 April 2017

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

1 reference

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7 April 2017

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

1 reference

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7 April 2017

An RNA polymerase II holoenzyme responsive to activators

1 reference

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7 April 2017

Tat transactivation: a model for the regulation of eukaryotic transcriptional elongation

1 reference

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29 September 2017

Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription

1 reference

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29 September 2017

Human and rodent transcription elongation factor P-TEFb: interactions with human immunodeficiency virus type 1 tat and carboxy-terminal domain substrate

1 reference

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29 September 2017

Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation

1 reference

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29 September 2017

Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme

1 reference

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29 September 2017

Tat activates human immunodeficiency virus type 1 transcriptional elongation independent of TFIIH kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

Interactions between human cyclin T, Tat, and the transactivation response element (TAR) are disrupted by a cysteine to tyrosine substitution found in mouse cyclin T

1 reference

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29 September 2017

Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat.

1 reference

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29 September 2017

The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein

1 reference

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29 September 2017

Transfer of Tat and release of TAR RNA during the activation of the human immunodeficiency virus type-1 transcription elongation complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

Stress and developmental regulation of the yeast C-type cyclin Ume3p (Srb11p/Ssn8p).

1 reference

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29 September 2017

Regulation of CDK7 substrate specificity by MAT1 and TFIIH.

1 reference

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29 September 2017

TFIIH: a key component in multiple DNA transactions

1 reference

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29 September 2017

Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II.

1 reference

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29 September 2017

Genetic analysis of the cofactor requirement for human immunodeficiency virus type 1 Tat function.

1 reference

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29 September 2017

The yeast UME5 gene regulates the stability of meiotic mRNAs in response to glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

The multifunctional TFIIH complex and transcriptional control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae

1 reference

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29 September 2017

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

Human chromosome 12 is required for optimal interactions between Tat and TAR of human immunodeficiency virus type 1 in rodent cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

29 September 2017

Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Control of eukaryotic cell cycle progression by phosphorylation of cyclin-dependent kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

The role of Cdk7 in CAK function, a retro-retrospective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Taking a new TAK on tat transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Suppression analysis reveals a functional difference between the serines in positions two and five in the consensus sequence of the C-terminal domain of yeast RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Specific interaction of the human immunodeficiency virus Tat proteins with a cellular protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Purification of P-TEFb, a transcription factor required for the transition into productive elongation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Expression and characterization of the trans-activator of HTLV-III/LAV virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Inhibition of in vivo and in vitro transcription by monoclonal antibodies prepared against wheat germ RNA polymerase II that react with the heptapeptide repeat of eukaryotic RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Fragments of the HIV-1 Tat protein specifically bind TAR RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

CTD kinase associated with yeast RNA polymerase II initiation factor b.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Sequences within the R region of the long terminal repeat activate basal transcription from the HIV-1 promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

2 June 2018

Partial purification and characterization of two distinct protein kinases that differentially phosphorylate the carboxyl-terminal domain of RNA polymerase subunit IIa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

27 November 2018

Cell cycle regulation of the p34cdc2/p33cdk2-activating kinase p40MO15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

27 November 2018

Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85957

27 November 2018

Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/10866664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth-related changes in phosphorylation of yeast RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/10866664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Residues Phosphorylatedin Vitroby Different C-terminal Domain Kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10866664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence that HIV-1 Tat stimulates RNA polymerase II carboxyl-terminal domain hyperphosphorylation during transcriptional elongation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10866664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast carboxyl-terminal domain kinase I positively and negatively regulates RNA polymerase II carboxyl-terminal domain phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10866664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10866664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.20.14.5077-5086.2000

0 references

PMC publication ID

0 references

PubMed publication ID

1 reference

PubMed publication ID

4 January 2017

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