(Q24648370)

https://api.crossref.org/works/10.1128/MCB.23.23.8902-8912.2003

31 March 2024

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1 reference

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31 March 2024

author name string

Yanping Zhang

1

0 references

Gabrielle White Wolf

2

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Krishna Bhat

3

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Aiwen Jin

4

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Theresa Allio

5

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Yue Xiong

7

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William A. Burkhart

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612427

full work available at URL

31 March 2024

language of work or name

English

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publication date

December 2003

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https://mcb.asm.org/content/23/23/8902.full.pdf

file format

Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612427

https://europepmc.org/articles/PMC262682

31 March 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612427

https://europepmc.org/articles/PMC262682?pdf=render

31 March 2024

file format

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open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612427

https://doi.org/10.1128/mcb.23.23.8902-8912.2003

31 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14612427

https://journals.asm.org/doi/pdf/10.1128/MCB.23.23.8902-8912.2003

31 March 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.23.23.8902-8912.2003

https://www.tandfonline.com/doi/pdf/10.1128/MCB.23.23.8902-8912.2003

31 March 2024

1 reference

https://api.crossref.org/works/10.1128/MCB.23.23.8902-8912.2003

Molecular and Cellular Biology

31 March 2024

published in

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volume

23

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issue

23

0 references

page(s)

8902-12

0 references

cites work

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

1 reference

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Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

7 April 2017

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Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

7 April 2017

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P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

7 April 2017

1 reference

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

7 April 2017

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Interaction of the HIV-1 rev cofactor eukaryotic initiation factor 5A with ribosomal protein L5

7 April 2017

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

7 April 2017

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Repression of p53-mediated transcription by MDM2: a dual mechanism

7 April 2017

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Mdm2 promotes the rapid degradation of p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

MDMX: a novel p53-binding protein with some functional properties of MDM2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Interaction between the retinoblastoma protein and the oncoprotein MDM2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Regulation of p53 stability by Mdm2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

p53, the cellular gatekeeper for growth and division

7 April 2017

1 reference

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An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Amplification of a gene encoding a p53-associated protein in human sarcomas

7 April 2017

1 reference

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Does the ribosome translate cancer?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Protein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiae

7 April 2017

1 reference

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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

7 April 2017

p53: puzzle and paradigm

1 reference

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Coordination of growth with cell division in the yeast Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Control of p53 ubiquitination and nuclear export by MDM2 and ARF.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

An encore for ribosome biogenesis in the control of cell proliferation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

MdmX protects p53 from Mdm2-mediated degradation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Regulation of the p53 tumor suppressor protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

E1A signaling to p53 involves the p19(ARF) tumor suppressor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

p14ARF links the tumour suppressors RB and p53.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Tumor surveillance via the ARF-p53 pathway.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

p19ARF links the tumour suppressor p53 to Ras

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262682

Non-syntenic amplification of MDM2 and MYCN in human neuroblastoma

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612427

12 December 2020

Inhibition of RNA synthesis by actinomycin D: Characteristic dose-response of different RNA species

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612427

12 December 2020

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612427

12 December 2020

RB regulates the stability and the apoptotic function of p53 via MDM2

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612427

12 December 2020

Effect of protein synthesis inhibitors and low concentrations of actinomycin D on ribosomal RNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14612427

12 December 2020

35

53

2736

Reifenberger G.

1993

1 reference

https://api.crossref.org/works/10.1128/MCB.23.23.8902-8912.2003

31 March 2024

Identifiers

1 reference

1 reference

1 reference

1 reference