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Gadd45 in the response of hematopoietic cells to genotoxic stress
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review article
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Europe PubMed Central
title
Gadd45 in the response of hematopoietic cells to genotoxic stress
(English)
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main subject
cell biology
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genotoxicity
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based on heuristic
inferred from title
author name string
Dan A Liebermann
series ordinal
1
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Barbara Hoffman
series ordinal
2
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language of work or name
English
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publication date
2007
1 reference
stated in
PubMed
published in
Blood Cells, Molecules and Diseases
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volume
39
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issue
3
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page(s)
329-35
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cites work
NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival
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Interaction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth control
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7 April 2017
Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth control
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PubMed Central
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7 April 2017
The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression
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7 April 2017
GADD45 induction of a G2/M cell cycle checkpoint
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PubMed Central
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7 April 2017
A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK
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7 April 2017
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
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7 April 2017
The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth
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7 April 2017
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
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PubMed Central
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7 April 2017
Isolation of interleukin 2-induced immediate-early genes
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Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C
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WAF1, a potential mediator of p53 tumor suppression
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7 April 2017
Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2
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7 April 2017
Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis
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7 April 2017
GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress
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PubMed Central
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7 April 2017
Oligomerization of human Gadd45a protein
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PubMed Central
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7 April 2017
Identification of a functional domain in a GADD45-mediated G2/M checkpoint
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7 April 2017
Cytokine response gene 6 induces p21 and regulates both cell growth and arrest
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7 April 2017
CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control
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PubMed Central
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7 April 2017
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45
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PubMed Central
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7 April 2017
The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1
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PubMed Central
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p21 is a universal inhibitor of cyclin kinases
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7 April 2017
Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways
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7 April 2017
Characterization of human Gadd45, a p53-regulated protein
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7 April 2017
Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokines
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7 April 2017
Genotoxic-stress-response genes and growth-arrest genes. gadd, MyD, and other genes induced by treatments eliciting growth arrest
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7 April 2017
Cell cycle checkpoints: preventing an identity crisis
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7 April 2017
NF-kappaB at the crossroads of life and death
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7 April 2017
Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
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PubMed Central
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7 April 2017
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
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7 April 2017
Role of JNK activation in apoptosis: a double-edged sword
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27 September 2017
Linking JNK signaling to NF-kappaB: a key to survival
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27 September 2017
NF-kappaB inducing kinase activates NF-kappaB transcriptional activity independently of IkappaB kinase gamma through a p38 MAPK-dependent RelA phosphorylation pathway
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27 September 2017
Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation
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27 September 2017
Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a
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27 September 2017
Map kinase signaling pathways and hematologic malignancies
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27 September 2017
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition
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27 September 2017
Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.
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27 September 2017
IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production.
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27 September 2017
Cooperative effects of genes controlling the G(2)/M checkpoint
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27 September 2017
p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes
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27 September 2017
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.
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27 September 2017
Mammalian G1 and G2 phase checkpoints
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27 September 2017
The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells
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27 September 2017
Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
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27 September 2017
Mechanisms of DNA excision repair
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27 September 2017
Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways.
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27 September 2017
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents
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27 September 2017
Mammalian genes induced by radiation; activation of genes associated with growth control.
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27 September 2017
Abrogation of p53 function affects gadd gene responses to DNA base-damaging agents and starvation
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27 September 2017
Signaling events controlling the molecular response to genotoxic stress.
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27 September 2017
Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: blocking p53-induced apoptosis unmasks G1 arrest.
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27 September 2017
Stress-induced JNK activation is independent of Gadd45 induction
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30 May 2018
Proliferating cell nuclear antigen: more than a clamp for DNA polymerases
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30 May 2018
Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin.
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30 May 2018
Hematopoietic cells from gadd45a-deficient and gadd45b-deficient mice exhibit impaired stress responses to acute stimulation with cytokines, myeloablation and inflammation.
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28 November 2018
Gadd45a and Gadd45b protect hematopoietic cells from UV-induced apoptosis via distinct signaling pathways, including p38 activation and JNK inhibition.
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28 November 2018
Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis
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PubMed Central
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28 November 2018
Ectopic expression of MyD118/Gadd45/CR6 (Gadd45beta/alpha/gamma) sensitizes neoplastic cells to genotoxic stress-induced apoptosis
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PubMed Central
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28 November 2018
MyD genes in negative growth control.
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28 November 2018
Protein-PCNA interactions: a DNA-scanning mechanism?
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28 November 2018
GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells
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Genomic instability in Gadd45a-deficient mice
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12 December 2020
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GADD45 regulates G2/M arrest, DNA repair, and cell death in keratinocytes following ultraviolet exposure
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PubMed
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Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53
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PubMed
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12 December 2020
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Cell survival and a Gadd45-factor deficiency
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PubMed
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12 December 2020
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Identifiers
DOI
10.1016/J.BCMD.2007.06.006
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1970698
OpenCitations bibliographic resource ID
1970698
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1970698
PMC publication ID
3268059
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1970698
PubMed publication ID
17659913
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1970698
ResearchGate publication ID
6178933
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