(Q53625972)

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Gadd45a and Gadd45b protect hematopoietic cells from UV-induced apoptosis via distinct signaling pathways, including p38 activation and JNK inhibition.

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

Gadd45a and Gadd45b protect hematopoietic cells from UV-induced apoptosis via distinct signaling pathways, including p38 activation and JNK inhibition. (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

apoptotic process

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Mamta Gupta

1

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

Shiv Kumar Gupta

2

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

Barbara Hoffman

3

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

Dan A Liebermann

4

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

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publication date

24 April 2006

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

281

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

26

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Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

17552-17558

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth

1 reference

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21 January 2018

CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control

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21 January 2018

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

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21 January 2018

The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells

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21 January 2018

Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation

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21 January 2018

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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Isolation of interleukin 2-induced immediate-early genes

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p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes

1 reference

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IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production.

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Myeloid differentiation (MyD)/growth arrest DNA damage (GADD) genes in tumor suppression, immunity and inflammation

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NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

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Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

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21 January 2018

Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

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21 January 2018

Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis

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21 January 2018

Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis

1 reference

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21 January 2018

Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a

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21 January 2018

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

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21 January 2018

NF-kappaB at the crossroads of life and death

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21 January 2018

Linking JNK signaling to NF-kappaB: a key to survival

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Missing pieces in the NF-kappaB puzzle

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21 January 2018

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

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21 January 2018

Map kinase signaling pathways and hematologic malignancies

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21 January 2018

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

1 reference

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21 January 2018

Role of JNK activation in apoptosis: a double-edged sword

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21 January 2018

Identifiers

10.1074/JBC.M600950200

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 May 2018

http://europepmc.org/abstract/MED/16636063

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