(Q40827754)

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Anti-tumorigenic effect of a K-ras ribozyme against human lung cancer cell line heterotransplants in nude mice

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Europe PubMed Central

PubMed publication ID

24 September 2017

Anti-tumorigenic effect of a K-ras ribozyme against human lung cancer cell line heterotransplants in nude mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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cancer cell line

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author name string

Zhang YA

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Nemunaitis J

2

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Scanlon KJ

3

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Europe PubMed Central

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24 September 2017

Tong AW

4

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Europe PubMed Central

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24 September 2017

publication date

1 December 2000

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Europe PubMed Central

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24 September 2017

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Europe PubMed Central

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24 September 2017

7

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Europe PubMed Central

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24 September 2017

23

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Europe PubMed Central

PubMed publication ID

24 September 2017

2041-2050

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Europe PubMed Central

PubMed publication ID

24 September 2017

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

1 reference

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Ras signalling and apoptosis

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Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

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Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression

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Impact of oncogenes in tumor angiogenesis: mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

1 reference

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Creation of human tumour cells with defined genetic elements

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Essential role for oncogenic Ras in tumour maintenance

1 reference

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Retroviral vector-mediated transduction of K-ras antisense RNA into human lung cancer cells inhibits expression of the malignant phenotype

1 reference

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Self-splicing of group I introns

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Therapeutic applications of ribozymes

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H-ras ribozyme-mediated alteration of the human melanoma phenotype

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Ribozyme cleaves rex/tax mRNA and inhibits bovine leukemia virus expression

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Inhibition of tumor growth by ribozyme-mediated suppression of aberrant epidermal growth factor receptor gene expression.

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Therapeutic efficacy of an adenovirus-mediated anti-H-ras ribozyme in experimental bladder cancer

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Reversal of transformed phenotype by monoclonal antibodies against Ha-ras p21 proteins.

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Gene therapy: adenovirus vectors.

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Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts

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Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats.

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Systematic analysis of repeated gene delivery into animal lungs with a recombinant adenovirus vector

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Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

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An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma

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Interleukin-2 gene transduction into freshly isolated lung adenocarcinoma cells with adenoviral vectors

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Hammerhead ribozyme specifically inhibits mutant K-ras mRNA of human pancreatic cancer cells

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Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods

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Prognostic value of K-ras mutations, ras oncoprotein, and c-erb B-2 oncoprotein expression in adenocarcinoma of the lung

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Safety evaluation of Ad5CMV-p53 in vitro and in vivo

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Suppression of Ki-ras p21 levels leading to growth inhibition of pancreatic cancer cell lines with Ki-ras mutation but not those without Ki-ras mutation

1 reference

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Hammerhead ribozymes targeted to the FBN1 mRNA can discriminate a single base mismatch between ribozyme and target

1 reference

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Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis

1 reference

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Use of recombinant adenovirus for metabolic engineering of mammalian cells.

1 reference

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7 January 2021

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inferred from DOI database lookup

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10.1038/SJ.GT.3301331

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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