(Q28548280)

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Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses

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Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses (English)

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Takashi Nakakura

3

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Takashi Nakakura

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Takashi

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Nakakura

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26070068%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Mitsuhiro Arisawa

12

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Mitsuhiro Arisawa

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Mitsuhiro

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Arisawa

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13 June 2020

16

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Koichi Sato

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Koichi

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Sato

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13 June 2020

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Ayaka Tobo

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13 June 2020

Masayuki Tobo

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Masayuki

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13 June 2020

Masashi Ebara

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Masashi

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Ebara

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13 June 2020

Hideaki Tomura

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Tomura

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13 June 2020

Chihiro Mogi

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Mogi

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13 June 2020

Dong-Soon Im

7

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Dong-Soon

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Im

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13 June 2020

Naoya Murata

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Murata

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13 June 2020

Atsushi Kuwabara

9

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Atsushi

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Kuwabara

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13 June 2020

Saki Ito

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Saki

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Ito

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13 June 2020

Hayato Fukuda

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Fukuda

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13 June 2020

Satoshi Shuto

13

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Satoshi

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Shuto

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13 June 2020

Michio Nakaya

14

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Michio

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Nakaya

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13 June 2020

Hitoshi Kurose

15

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Hitoshi

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Kurose

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13 June 2020

Fumikazu Okajima

17

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Fumikazu

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Okajima

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13 June 2020

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2015

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13 June 2020

10

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13 June 2020

6

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13 June 2020

e0129334

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13 June 2020

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Creative Commons Attribution 4.0 International

12 June 2015

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April 2022 Public Data File from Crossref

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Regulation of inflammation by extracellular acidification and proton-sensing GPCRs

1 reference

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Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis

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19 March 2017

Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway

1 reference

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19 March 2017

Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms

1 reference

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Prostaglandin I(2) production and cAMP accumulation in response to acidic extracellular pH through OGR1 in human aortic smooth muscle cells

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Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells

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TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor

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19 March 2017

G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine

1 reference

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19 March 2017

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Sphingosylphosphorylcholine and lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction

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19 March 2017

Identification of a molecular target of psychosine and its role in globoid cell formation

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19 March 2017

Role of extracellular calcium and mitochondrial oxygen species in psychosine-induced oligodendrocyte cell death

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Ionotropic and metabotropic proton-sensing receptors involved in airway inflammation in allergic asthma

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29 September 2017

Acidic pH increases cGMP accumulation through the OGR1/phospholipase C/Ca(2+)/neuronal NOS pathway in N1E-115 neuronal cells

1 reference

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Acidic tumor microenvironment and pH-sensing G protein-coupled receptors

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Proton-sensing ovarian cancer G protein-coupled receptor 1 on dendritic cells is required for airway responses in a murine asthma model

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29 September 2017

Each one of certain histidine residues in G-protein-coupled receptor GPR4 is critical for extracellular proton-induced stimulation of multiple G-protein-signaling pathways

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1 reference

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12 December 2020

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Antagonist-stimulated internalization of the G protein-coupled cholecystokinin receptor

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https://pubmed.ncbi.nlm.nih.gov/26070068

12 December 2020

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Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia

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https://pubmed.ncbi.nlm.nih.gov/26070068

12 December 2020

based on heuristic

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10.1371/JOURNAL.PONE.0129334

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13 June 2020

2015PLoSO..1029334T

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24 November 2022

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13 June 2020

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13 June 2020

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