Antiinflammatorium nonsteroidale

Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt.

Antiinflammatoria nonsteroidalia, breve AINS sunt familia medicamentorum, quae per inhibitionem enzymorum cyclooxygenasium - deinde inhibitione synthesis prostaglandinorum effectus suos contra inflammationem (=anti-inflammativos) efficiunt.

Effectus adversi sunt nephropathiae, ulcera gastrointestinalia^[1], reactiones allergicae (ut bronchoconstrictio, angiooedema, urticaria, dermatitis), etiam infarctus cordis^[2].

Exempla AINS

Historia

Annis 1960 ineunte effectus adversarii glucocorticoidorum, quae tum saepe in inflammationes tractandi usa erant, cognoscebantur. Cum familia nova antiinflammatoriorum non-steroidalium medicina et pharmacologia fiduciam recuperari conabantur^[3].

Notae

↑ Lanas A., Chan F. K. L. (Aug 2017). "Peptic Ulcer Disease". Lancet 390 (10094): 613-24
↑ "Risk of Acute Myocardial Infarction With NSAIDs in Real World Use: Bayesian Meta-Analysis of Individual Patient Data". BMJ 357 (j1909). May 2017
↑ Buer J. K. (Oct 2014). "Origins and impact of the term 'NSAID'". Inflammopharmacology 22 (5): 263-7

Nexus interni

Dolor

Nexus externi

stipula

Haec stipula ad medicinam spectat. Amplifica, si potes!

[1] Lanas A., Chan F. K. L. (Aug 2017). "Peptic Ulcer Disease". Lancet 390 (10094): 613-24

[2] "Risk of Acute Myocardial Infarction With NSAIDs in Real World Use: Bayesian Meta-Analysis of Individual Patient Data". BMJ 357 (j1909). May 2017

[3] Buer J. K. (Oct 2014). "Origins and impact of the term 'NSAID'". Inflammopharmacology 22 (5): 263-7

[1]

[2]

[3]