Amiodaron
Tampilan
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Nama sistematis (IUPAC) | |
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine | |
Data klinis | |
Nama dagang | Cordarone, Nexterone, Pacerone, others |
AHFS/Drugs.com | monograph |
MedlinePlus | a687009 |
Data lisensi | US Daily Med:pranala |
Kat. kehamilan | C(AU) |
Status hukum | Harus dengan resep dokter (S4) (AU) ℞-only (CA) ℞-only (US) |
Rute | By mouth, intravenous, intraosseous |
Data farmakokinetik | |
Bioavailabilitas | 20–55% |
Ikatan protein | 96% |
Metabolisme | Liver |
Waktu paruh | 58 d (range 15–142 d) |
Ekskresi | Primarily liver and bile |
Pengenal | |
Nomor CAS | 1951-25-3 ![]() |
Kode ATC | C01BD01 |
PubChem | CID 2157 |
Ligan IUPHAR | 2566 |
DrugBank | DB01118 |
ChemSpider | 2072 ![]() |
UNII | N3RQ532IUT ![]() |
KEGG | D02910 ![]() |
ChEBI | CHEBI:2663 ![]() |
ChEMBL | CHEMBL633 ![]() |
Data kimia | |
Rumus | C25H29I2NO3 |
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Amiodaron adalah obat antiaritmia, FDA Amerika Serikat (Food and Drug Administration), telah memberi label amiodaron untuk pengobatan aritmia ventrikel yang mengancam jiwa, obat ini umumnya digunakan di luar label untuk mengobati takiaritmia supraventrikular seperti fibrilasi atrium serta untuk pencegahan takiaritmia ventrikel (VT) pada risiko tinggi pasien.[1][2][3]
Referensi
[sunting | sunting sumber]- ^ Voulgareli, Ilektra; Chronaiou, Alexandra; Tsoukalas, Dionisios; Tsoukalas, George (2018-12). "A rare case of lipoid pneumonia attributed to amiodarone". Pneumonia. 10 (1). doi:10.1186/s41479-018-0056-3. ISSN 2200-6133.
- ^ Soar, Jasmeet; Perkins, Gavin D.; Maconochie, Ian; Böttiger, Bernd W.; Deakin, Charles D.; Sandroni, Claudio; Olasveengen, Theresa M.; Wyllie, Jonathan; Greif, Robert (2019-01). "European Resuscitation Council Guidelines for Resuscitation: 2018 Update – Antiarrhythmic drugs for cardiac arrest". Resuscitation. 134: 99–103. doi:10.1016/j.resuscitation.2018.11.018. ISSN 0300-9572.
- ^ Serhan Özcan, Kazım; Zengin, Ahmet; Tatlısu, Adem; Aruğarslan, Emre; Nurkalem, Zekeriya (2014-02). "Anaphylactic shock associated with intravenous amiodarone". Journal of Cardiology Cases. 9 (2): 61–62. doi:10.1016/j.jccase.2013.10.001. ISSN 1878-5409.
Kategori:
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