Advancing Health

Orin Bloch, M.D.
Professor
Neurological Surgery

1.  Stereotactic radiosurgery and peripheral immune system activation in patients with brain mestastases from non-small cell lung cancer
2.  Longitudinal immune profiling of patients with Glioblastoma  
3.  Flourescence lifetime technique for detection of radiation necrosis vs glioma

David Brandman, M.D., Ph.D.
Assistant Professor
Neurological Surgery

Branden Cord, M.D., Ph.D.

Neurological Surgery

1. Feasibility Study of the treatment of Acute Ischemic Stroke using the NOVIS Transcarotid Neuroprotection System In Transcarotid Embolectomy (the NITE1 study) SRM–2019-01

Neurological Surgery

1. ASPIRE - An Assessment of P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion with Instrumentation
2. Abbvie M16-077 - A Randomized, Double-Blind, Placebo-Controlled Proof of Concept Study to Assess the Safety and Efficacy of Elezanumab in Acute Traumatic Cervical Spinal Cord Injury
3. The Role Of Cervical Spinal Stenosis In The Production Of Cervicogenic Headache
4. Multifactorial analysis of admission and outcomes of spine trauma
5. Randomized, Controlled, Single-blind Study of Probable Benefit of the Neuro-Spinal Scaffold™for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury as Compared to Standard of Care
6. A Prospective, Randomized, Multi-Center, Open-Label Pilot Study of Infuse® Bone Graft with Mastergraft® Strip and Posterior Fixation for Posterolateral Fusion (PLF) Treatment of MultiLevel Degenerative Lumbosacral Spinal Conditions
7. A Pivotal Clinical Trial Evaluating the Safety and Effectiveness of Adherus™ AutoSpray and Adherus™ AutoSpray ET Dural Sealant When Used as a Dural Sealant in Spinal Procedures
8. The INSPIRE Study: InVivo Study of Probable Benefit for the Neuro-Spinal Scaffold for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury
9. A Concurrently Controlled Study of the LimiFlex™ Paraspinous Tension Band in the Treatment of Lumbar Degenerative Spondylolisthesis with Spinal StenosisEmpirical Spine
10. A Multicenter, Randomized, Double-blind, Sham-controlled, Comparative Study of SI-6603 in Subjects with Lumbar Disc Herniation (Phase 3)
11. Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse™ Bone Graft and The Capstone™ Spinal System with Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine - pending

Neurological Surgery

1. Quantitative measurement of spinal cord function in degenerative cervical myelopathy: a prospective observational longitudinal cohort study

Ryan Martin, M.D.
Assistant Professor
Departments of Neurological Surgery and Neurology  
Contact Dr. Martin at [email protected]

1. Imaging of glial activation and risk for post-traumatic epilepsy
2. Traumatic Brain Injury Outcomes
3. The UCD-DGMC TBI Neural Network-Precision Medicine Paradigm for Complex Trauma
4. A Phase 4 Randomized Clinical Trial of Andexanet alfa in Acute Intracranial Hemorrhage in Patients Receiving an Oral Factor Xa Inhibitor - pending

Neurological Surgery

1. Dual frequency, dual region deep brain stimulation of the subthalamic nucleus in Parkinson’s disease
2. Adverse Childhood Experiences and Traumatic Brain Injury
3. Exploration of prognostic factors in traumatic intraventricular hemorrhage
4. Incidence and treatment of cerebral venous sinus thrombosis
5. TBI Outcome Study
6. DBS Cognition
7. The effect of hyperoxia in pediatric TBI
8. PENS (A placebo-controlled efficacy in iNPH shunting (PENS) Trial -Pending
9. TRACK-TBI - Clinical Evaluation of the i-STAT TBI Test -Pending
10. Lidocaine infusion in glioblastoma multiforme
11. Subthalamic nucleus activity during cognitive processing
12. Randomized trial of CSF shunting in patients with normal pressure hydrocephalus

Neurological Surgery

1. NOVEL - Noninvasive intracanial pressure from transcranial doppler ultrasound 

Ben Waldau, M.D.
Professor
Neurological Surgery
Contact Janice Wang-Polagruto at [email protected]

1.   Clinical Use of a Humanitarian Use Device (HUD), the Wingspan Stent System with Gateway PTA Balloon Catheter, for the Treatment of Intracranial Atherosclerotic Disease
2.   Prospective transcranial doppler analysis of aneurysmal subarachnoid hemorrhage patients
3.   Influence of Temozolomide-induced suppression of adult hippocampal neurogenesis on spatial learning and memory
4.   Single institution retrospective review of delayed clip slippage after aneurysm clipping
5.   Spatial memory after aneurysmal subarachnoid hemorrhage
6.   Inter-observer reliability of a new grading scale to assess coiling of cerebral aneurysms

Neurological Surgery

1. CURE - Genetic and Protein Biomarkers of Post-traumatic Epilepsy to Improve Prediction of PTE: a Prospective Study in an Enriched Patient Population - DoD - Citizens United for Research in Epilepsy
2. A Prospective Multi-Center Cohort Study of Metagenomic Deep Sequencing for Diagnosis of Acute Infectious Diseases
3. Brain Oxygen Optimization in Severe Traumatic Brain Injury—Phase 3 (BOOST-3)
4. The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBios4Rx)
5. Bio-BOOST: Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial

Neurological Surgery

1. Selection of children with severe TBI for neurosurgical intervention. External validation of a clinical guideline
2. Predicting the outcome of children with non-accidental traumatic brain injury: Utility of the GCS versus GCS-P in children less than 3 years of age
3. Long term outcome of moderate to severe TBI in children

4. Limiting radiation exposure in children