Talk:Vanillin

Ethyl or Methyl ?

The article starts by differentiating between methyl and ethyl, but does not say whether ethyl occurs naturally in vanilla. Nor does it say which type is produced by which artificial processes. I am no chemist, but I think the difference is important especially if you are concerned about natural compounds versus artificial ones. Methyl, it can be argued, is naturally occuring, but it is unclear from this article if ethyl is. —Preceding unsigned comment added by 70.19.240.155 (talk) 21:54, 28 December 2007 (UTC)

ethyl does occour naturally. I do not know if it occours naturally in vanilla. 194.231.192.194 (talk) 22:02, 16 November 2008 (UTC)

Also, readership needs to know its role in vanilloid receptors as a possible antinociceptive agent that may combat some of the painful and irritating effects of capsaicin or resiniferatoxin (RTX), found in the contents of pepper spray. If anyone knows, please elucidate. — Preceding unsigned comment added by 98.121.172.71 (talk) 00:25, 15 December 2012 (UTC)

Prospects

This article is starting to look pretty good. Many thanks to the anonymous editor(s) who added so much. The only aspect I can think of that isn't fully covered is the history, i.e., who discovered it and named it, things like that. It would be nice to know why it smells so, as in what olfactory receptor it binds to and what its aromatophore is, but perhaps no one knows. —Keenan Pepper 02:13, 14 September 2006 (UTC)

Separating notes from references

If I felt it was purely a matter of style, I wouldn't mention it, but I think it's also a matter of functionality: it's much easier (for me, at least) to read and edit the text when the <ref> tags contain as little as possible; it's easier (for me, at least) to read and edit references when the parts of the template are broken down line by line, and it's easier to make notes that are more than simply a bibliographic citation, when the notes are a separate thing from the bibliographic citations. 128.174.36.221 18:39, 14 September 2006 (UTC)

Please see today's FA Operation Ten-Go, for an example of this format used well. A brief view of recent FA's finds some kind of separation of notes from references in about half of these articles. 128.174.36.221 18:47, 14 September 2006 (UTC)

Reference

Alvaro L. Mathias, Mary I. Lopretti & Alirio E. Rodrigues (1995). "Chemical and Biological Oxidation of Pinus pinaster Lignin for the Production of Vanillin". J . Chem. Tech. Biotechnol. 64: 225–234.

Uses

"Vanillin can also be found in bottles of Buckfast Tonic Wine (made by the monks of Buckfast Abbey) sold in the United Kingdom. It is not however found in the bottles sold in the Republic of Ireland.[citation needed]"

Removing this as non-notable. Vanillin is added to countless products, what's so special about this one?--Eloil 22:28, 23 April 2007 (UTC)

Myth Suspect

Was Vanillin was used as a rat poison during a World War? If so, which one and any details? Some elderly won't allow vanillin in their diet or baking needs. Coumarin, an extract of the Tonka tree, smells like vanillin. Perhaps, because a small amount fills a large space, vanillin could have been added to poison to attract rodents.

The letal dose of vanillin in rats is 1580 mg per kg of body weight. 194.231.192.194 (talk) 22:02, 16 November 2008 (UTC)

History and other misc info

From about 1961 to around 1976, vanillin and other chemically similar compounds were manufactured at Zimpro Products in Rothschild, WI. The process equipment, technology and some key personnel were acquired by ITT-Rayonier and moved to a site adjacent to a soft wood sodium-based sulphite pulp mill in Hoquiam,WA. Opening in March 1979, the plant produced methyl-vanillin until January 1993 following the pulp mill closure.

The Monsanto Chemical company manufactured vanillin in Seattle,WA from 1952 till ? when purchased by Rhone-Poulanc which closed (1981?).

China made vanillin available for export to the US early 1990.

Borregaard in Norway produces vanillin.

In 1985, under the name New Coke, Coca-Cola once tried to change its formulation based on vanilla beans to using synthetic vanillin. Not only was it not successful but severely affected the African country Madagascar which was heavily dependant on Vanilla bean exports.

Ethylvanillin is also called Bourbonal.

Vanillin is able to be purified by sublimation.

Certain elements can change the color of the vanillin crystal from off white to pink or yellow.

A dime sized amount of vanillin, evenly dispersed, can be noticed throughout an enclosed football- type stadium.

68.39.27.109 (talk) 00:18, 12 March 2008 (UTC)

WikiProject Food and drink Tagging

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This is a poorly worded sentence; what does it mean?

In other foods, heat treatment evolves vanillin from other chemicals--Filll (talk | wpc) 15:05, 20 March 2009 (UTC)

It means what it says. In some foods, heat generates (evolves) vanillin from other chemicals in the food. Wjousts (talk) 16:53, 20 March 2009 (UTC)

In other words, there's a perfectly good word that everyone knows that works, but the writer chose to use jargon instead. I have changed this to the more encyclopedic term "generates," as given above. It's more encyclopedic because people not versed in (organic) chemistry can understand it.— trlkly 14:25, 31 March 2012 (UTC)

Has Ethyl vanillin been used as a food additive....???

http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=W246409%7CALDRICH&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&F=SPEC --222.64.211.128 (talk) 00:13, 23 August 2009 (UTC)

http://www.usp.org/pdf/EN/fcc/2009-05-28_Errata_FCC6_Version_2.pdf --222.64.211.128 (talk) 00:18, 23 August 2009 (UTC)

What is the rational of using ethyl vanillin as a food additive...??? Are there any evidences which demonstrate the compound is naturally occuring...???

http://scholar.google.com.au/scholar?hl=en&q=allintitle%3A+Vanilla+ethyl+vanillin&btnG=Search

http://scholar.google.com/scholar?q=allintitle%3A+Vanilla+ethyl+vanillin&hl=en&btnG=Search --222.64.211.128 (talk) 00:28, 23 August 2009 (UTC)

Please bear in mind that vanilla extract is a processed product--222.64.211.128 (talk) 00:26, 23 August 2009 (UTC)

http://scholar.google.com.au/scholar?as_q=Vanilla+extract+supercritical+fluid&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=title&as_sauthors=&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en --222.64.211.128 (talk) 00:33, 23 August 2009 (UTC)

See Steam distillation and Supercritical fluid extraction for further info--222.64.211.128 (talk) 00:51, 23 August 2009 (UTC)

Uses of vanillin in biochemistry & chemotherapy

I'm not sure if this is appropriate/relevant so I thought I should ask first. Vanillin has some anti-mutagenic properties and is an inhibitor of the non-homologous end-joining DNA repair pathway. It's currently being investigated as a chemotherapy agent/co-agent to combat cancer, as it's been shown to help decrease angiogenesis and help prevent metastasis. The reason I'm not sure if it's relevant including this is that (as far as I can tell from looking at the literature) it's not yet at the point where it's being used in humans so it isn't really medically relevant yet. Anyone know whether this is relevant/notable enough to go in this section? I haven't edited much of anything on wikipedia before so I figured I should probably ask first ;) P.S. Some references: http://www.ncbi.nlm.nih.gov/pubmed/19679064?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2 http://www.ncbi.nlm.nih.gov/pubmed/19368348?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4 http://www.ncbi.nlm.nih.gov/pubmed/17178418?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=14

There's lots more, just type 'vanillin + cancer' or 'vanillin + DNA repair' into pubmed. Antimorph (talk) 15:18, 25 January 2010 (UTC)

Medical Use

I just came across an old metal can of Vanillin from the Mallinkrodt Chemical Works. The caution on the can says... "CAUTION: To be used only by or on the prescription of a physician, dentist or veterinarian, if used medicinally." How would this have been used medicinally? me too

The can says "Mallinkrodt Chemicals Standard for Over Half a Century" Mallinkrodt was founded in 1867, so this can must be post 1917. The can was in an old sewing machine that has not been used since the 1950s. — Preceding unsigned comment added by 98.220.115.196 (talk) 20:46, 31 October 2011 (UTC)

NMR

If you guys have the NMR spectra of a compound why not link to it?

https://en.wikipedia.org/wiki/File:Vanillin_proton_NMR.gif

It makes no sense for it not to be there someplace. — Preceding unsigned comment added by 172.248.197.0 (talk) 01:34, 12 October 2016 (UTC)

Old World evidence article reference

Since access to the Journal of Archaeological Science article is restricted at its original site perhaps there should also be a reference to a pdf file here and/or at Academia (though that sometimes has size problems when viewed). Mcljlm (talk) 22:56, 22 May 2022 (UTC)

References