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Pasquale Calabrese

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Pasquale Calabrese
Born (1961-02-27) 27 February 1961 (age 63)
Naples
NationalityItalian
CitizenshipItalian
Known fordiagnosis of neuropsychological and behavioral disturbances in neuropsychiatric patients, focus on multiple sclerosis, Parkinson's disease and Alzheimer's disease
AwardsLundbeck-Institute Teaching Award in neuropsychology and neuropsychometry of Old-Age-Psychiatry (2004/2006), German Brain Research Award in geriatrics (2011)
Scientific career
FieldsNeurology, Clinical neurology, Neurophysiology, Clinical neurophysiology, Neuroscience, Clinical neuroscience, Neuropsychology
InstitutionsUniversity of Basel

Pasquale Calabrese born 27 February 1961 in Naples, Italy, is an Italian professor of clinical neurosciences at the University of Basel, Faculty of Psychology, Department of Molecular and Cognitive Neurosciences. He is a neuroscientist, experimental neurologist and medical neuropsychologist.

Biography

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Calabrese received his academic formation in psychology, medicine, biology and philosophy at the University of Konstanz, University of Zurich, Ruhr University Bochum and University of Bielefeld from 1983 to 1989. He received a diploma in psychology at the University of Konstanz in 1991. He received his PhD in his major clinical neuropsychology and in his minor clinical neurology in 1997. In 1999 he was appointed guest professor in neurosciences at the International Institute of Genetics and Biophysics (IIGB) of the Italian Research Association. In 2004 Calabrese received his habilitation from the Faculty of Medicine of the University of Bochum and received the Venia legendi in Experimental Neurology and Medical Neuropsychology. From 1991 to 2008 he was Head of the Department of Neuropsychology and Behavioral Neurology and Director of the Memory Clinic at the University Hospital Bochum-Langendreer (Germany). From 2010 he worked in the same position at the Neurocenter Southern Switzerland, Lugano (Switzerland). Since 2011 he is titular-professor of clinical neuroscience at the University of Basel, where he also heads the Neuropsychology and Behavioral Neurology Unit at the Department of Molecular and Cognitive Neuroscience and Head of Neuropsychology at the University Hospital's MS Center.[1] He also serves as a clinical neuropsychological expert for the Swiss Insurance Medicine and consulting clinical neuropsychologist at the department of Neurosurgery of the University of Basel where he is a member of the awake-craniotomy team.

Clinical-scientific contribution

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Calabrese's clinical research focus is in the field of diagnosis of neuropsychological and behavioral disturbances in neuropsychiatric patients, with a focus on Multiple Sclerosis, Parkinson's disease and Alzheimer's disease. He is involved in the conceptualization of clinical trails in the field of behavioral neurology and psychiatry.

In his single-case studies and essays he pursues an idiographic-constructivist-neuro-evolutive approach. During his training and affiliation in the lab of Hans Markowitsch, he was mainly involved in some fundamental clinical studies to investigate the functional neuroanatomical and neuropsychological correlates of retrograde amnesia after brain damage.[2][3][4]

In addition, his clinical research area relates to the study of neuropsychiatric dysfunctions and quality of life in multiple sclerosis[5][6][7][8] and other neuropsychiatric disorders Stress-related dysfunctions[9][10] and also in patients with Parkinson's disease.[11] Calabrese is co-developer of neuropsychological screening procedures and neuropsychometric test batteries that have found manyfold applications in clinical practice. His neuropsychometric oeuvre includes the development of clinical screening tools, such as the DemTect[12] for the investigation of patients with dementia, MUSIC, a screening test for the detection of cognitive deficits in multiple sclerosis and the PANDA,[13] a cognitive test for the detection of cognitive disorders in Parkinson's disease.[14] He is also co-author of the German-language translation and validation of the revised Wechsler Memory Scale (WMS-R) for the detection of memory disorders in brain-damaged subjects.[15][16][17][18] The neurobehavioral monitoring of patients with brain tumors during awake craniotomy and the expert assessment and assessment of damage-related behavioral changes are also part of his clinical specialty.[19]

Honors and awards

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  • September 2004: Lundbeck-Institute Teaching Award in neuropsychology and neuropsychometry of Old-Age-Psychiatry
  • July 2006: Lundbeck-Institute Teaching Award in neurology and psychiatry
  • July 2011: German Brain Research Award in geriatrics (together with E. Kalbe and J. Kessler, MPI of neurological research, Cologne) for the development of neuropsychological diagnostics in Dementia“

Memberships

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  • Since 2013: President of the Teaching-Committee ”Neuropsychology and Psychotherapy in Multiple Sclerosis” of the Swiss Multiple Sclerosis Society (SMSG)
  • Member of the Scientific Advisory Board of the German Society of Anti Aging and Preventive Medicine (GSAAM)
  • Executive member of the Communication Committee of the European Academy of Neurology (EAN)
  • Since 2013: Member of the Scientific Advisory Board and Member of the Scientific Committee of the Swiss MS Registry
  • Since 2012: Member of the senate (Regenz) of the University of Basel

Publications

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References

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  1. ^ P. Calabrese CV
  2. ^ Markowitsch, H.J., Calabrese, P., Liess, J., Haupts, M., Durwen, H.F. & Gehlen, W. (1993). Retrograde amnesia after traumatic injury of the temporo-frontal cortex. Journal of Neurology, Neurosurgery and Psychiatry, 56, 988-99.
  3. ^ Calabrese, P., Markowitsch, H.J., Durwen, H.F., Widlitzek, B., Haupts, M., Holinka, B. & Gehlen, W. (1996). Right temporofrontal cortex as critical locus for the ecphory of old episodic memories. Journal of Neurology, Neurosurgery, and Psychiatry, 61, 304-310
  4. ^ Markowitsch, H.J., Calabrese, P., Neufeld, H., Gehlen, W. & Durwen, H.F. (1999). Retrograde amnesia for world knowledge and preserved memory for autobiographic events. A case report. Cortex, 35, (243-252)
  5. ^ Tiemann, L., Penner, I.K., Haupts, M., Schlegel, U. & Calabrese, P. (2009). Cognitive decline in Multiple Sclerosis – impact of topographic lesion distribution on differential cognitive deficit patterns. Multiple Sclerosis, 10, 1164-1176
  6. ^ Calabrese, P., Haupts, M., Babinsky, R., Markowitsch, H.J. & Gehlen, W. (1993). Alltagsgedächtnisleistungen bei Multipler Sklerose. Zeitschrift für Neuropsychologie, 4, 4-16
  7. ^ Calabrese P, Kobelt G, Berg J, Capsa D, Eriksson J; European Multiple Sclerosis Platform (2017). New insights into the burden and costs of multiple sclerosis in Europe: Results for Switzerland. Mult Scler. 2017 Aug;23(2_suppl):192-203
  8. ^  Pasquale Calabrese (Autor), Claudia Engel (Mitwirkende), Pedro Michael Faustmann (Mitwirkende) u. a. Multiple Sklerose und Kognition. Thieme 2012.
  9. ^ Giese, M., Unternährer, E., Hüttig, H, Beck, J., Brand, S., Calabrese, P., Holsboer-Trachsler, E. & Eckert, A. (2013). BDNF – an indicator of insomnia. Molecular Psychiatry (19), 151-152
  10. ^ Ness D, Calabrese P. (2016). Stress Effects on Multiple Memory System Interactions. Neural Plast. 2016;2016:4932128
  11. ^ Tiemann, L., Penner, I.K., Haupts, M., Schlegel, U. & Calabrese, P. (2009). Cognitive decline in Multiple Sclerosis – impact of topographic lesion distribution on differential cognitive deficit patterns. Multiple Sclerosis, 10, 1164-1176
  12. ^ Kessler, J., Calabrese, P., Kalbe, E. & Berger, F. (2000). DemTect. Ein neues Screening-Verfahren zur Unterstützung der Demenzdiagnostik, Psycho,6, 343-347. n.g./C
  13. ^ Kalbe, E., Calabrese, P., Fengler, S. & Kessler, J. (2013). DemTect, PANDA, EASY, and MUSIC: Cognitive Screening Tools with Age Correction and Weighting of Subtests According to Their Sensitivity and Specificity. Journal of Alzheimers Disease, 34, 813-834
  14. ^ Kalbe, E., Calabrese, P., Kohn, N., Hilker, R., Riedel, O., Wittchen, H.U., Dodel, R., Otto, J. Ebersbach, G. & Kessler, J. (2008). Screening for cognitive deficits in Parkinson's disease with the Parkinson neuropsychometric dementia assessment (PANDA) instrument. Parkinsonism and Related Disorders, 16, 32-49. MED; IF=2.40/B
  15. ^ Calabrese, P., Fink, G.R., Markowitsch, H.J., Kessler, J., Durwen, H., Liess, J., Haupts, M., & Gehlen, W. (1994). Left hemispheric neuronal heterotopia. A PET, MRI, EEG, and neuropsychological investigation of a university student. Neurology, 44, 302-305
  16. ^ Markowitsch, H.J., Calabrese, P., Würker, M., Durwen, H.F., Kessler, J., Babinsky, R., Brechtelsbauer, D., Heuser, L. & Gehlen, W. (1994). The amygdala’s contribution to memory - A PET-study on two patients with Urbach-Wiethe disease. NeuroReport, 5, 1349-1352
  17. ^ Calabrese, P., Markowitsch, H.J., Harders, A.G., Scholz, A. & Gehlen, W. (1995). Fornix damage and memory: A case report. Cortex, 31, 555-564
  18. ^ Doolittle ND, Korfel A, Lubow MA, Schorb E, Schlegel U, Rogowski S, Fu R, Dósa E, Illerhaus G, Kraemer DF, Muldoon LL, Calabrese P, Hedrick N, Tyson RM, Jahnke K, Maron LM, Butler RW, Neuwelt EA. (2013). Long-term cognitive function, neuroimaging, and quality of life in primary CNS lymphoma. Neurology, 2;81(1):84-92
  19. ^ Diehl, R.R., Wittlieb-Verpoort, E., Ringendahl, H., Calabrese, P. & Wilhelm, H. (1999). Der Neuropsychologe in der Akutklinik - Beschreibung eines Berufsbildes. Zeitschrift für Neuropsychologie, 10, 3-12
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