Ammasi Periasamy
Ammasi Periasamy | |
|---|---|
| Alma mater | University of Madras Indian Institute of Technology |
| Scientific career | |
| Institutions | University of Washington University of Virginia |
| Thesis | Molecular imaging : FRET microscopy and spectroscopy (1984) |
Ammasi Periasamy is an Indian American biophysicist who is a professor at the University of Virginia. He works on light microscopy, including the molecular imaging of living cells. He has developed a range of imaging systems, including confocal, multi-photon and fluorescence-lifetime imaging microscopy base devices.
Early life and education
[edit]Periasamy was born in India. He trained at the University of Madras and the Indian Institutes of Technology.[1] After earning his doctorate in 1984, Periasamy moved to the University of Washington for a postdoctoral research position.[1]
Research and career
[edit]Periasamy founded the W. M. Keck Centre for Cellular Imaging. His research considers the development of microscopy for imaging of living cells. He has designed various advanced modalities, including multi-photon and confocal approaches. In particular, Periasamy is interested in understanding protein-protein interactions and the monitoring of physical parameters in cancer cells.[2] Periasamy was one of the first researchers to demonstrate fluorescence-lifetime imaging microscopy (FLIM) and fluorescence lifetime redox ratio (FLIRR).[3][4][5]
Selected publications
[edit]- Rajesh Babu Sekar; Ammasi Periasamy (1 March 2003). "Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations". Journal of Cell Biology. 160 (5): 629–633. doi:10.1083/JCB.200210140. ISSN 0021-9525. PMC 2173363. PMID 12615908. Wikidata Q24673219.
- Horst Wallrabe; Ammasi Periasamy (1 February 2005). "Imaging protein molecules using FRET and FLIM microscopy". Current Opinion in Biotechnology. 16 (1): 19–27. doi:10.1016/J.COPBIO.2004.12.002. ISSN 0958-1669. PMID 15722011. Wikidata Q30435991.
- Masilamani Elangovan; Horst Wallrabe; Ye Chen; Richard N Day; Margarida Barroso; Ammasi Periasamy (1 January 2003). "Characterization of one- and two-photon excitation fluorescence resonance energy transfer microscopy". Methods. 29 (1): 58–73. doi:10.1016/S1046-2023(02)00283-9. ISSN 1046-2023. PMID 12543072. Wikidata Q33185799.
References
[edit]- ^ a b "| Department of Biology, U.Va". bio.as.virginia.edu. Retrieved 2023-01-27.
- ^ Periasamy, Ammasi (2006-04-14), "Cellular Imaging", in Webster, John G. (ed.), Encyclopedia of Medical Devices and Instrumentation, Hoboken, NJ, USA: John Wiley & Sons, Inc., pp. emd327, doi:10.1002/0471732877.emd327, ISBN 978-0-471-73287-7, retrieved 2023-01-27
- ^ "Ammasi Periasamy". www.leica-microsystems.com. Retrieved 2023-01-27.
- ^ FLIM MICROSCOPY IN BIOLOGY AND MEDICINE. [S.l.]: CRC PRESS. 2020. ISBN 978-0-367-57730-8. OCLC 1156990580.
- ^ "At UVA's Keck Center, Researchers Peer Deep Into Inner Workings of Cells". UVA Today. 2017-12-14. Retrieved 2023-01-27.
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