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AMY1A

From Wikipedia, the free encyclopedia
AMY1A
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesAMY1A, AMY1, amylase, alpha 1A (salivary), amylase alpha 1A (salivary), amylase alpha 1A
External IDsOMIM: 104700; HomoloGene: 133998; GeneCards: AMY1A; OMA:AMY1A - orthologs
EC number3.2.1.1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004038
NM_001008221

n/a

RefSeq (protein)

NP_001008220
NP_001333709
NP_001008222
NP_004029
NP_001008219

n/a

Location (UCSC)Chr 1: 103.66 – 103.66 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Alpha-amylase 1 is an enzyme that in humans is encoded by the AMY1A gene.[3] This gene is found in many organisms.

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein.[3]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000237763Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: AMY1A amylase, alpha 1A; salivary".
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Further reading

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