Potassium iodate: Difference between revisions
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 22856 |
| ChemSpiderID = 22856 |
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| DrugBank = DB15923 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = I139E44NHL |
| UNII = I139E44NHL |
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| Odor = odorless |
| Odor = odorless |
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| Density = 3.89 g/cm<sup>3</sup> |
| Density = 3.89 g/cm<sup>3</sup> |
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| Solubility = 4.74 g/100 mL (0 °C) <br> 9.16 g/100 mL (25 °C) <br> 32.3 g/100 mL (100 °C) |
| Solubility = 4.74 g/100 mL (0 °C) <br /> 9.16 g/100 mL (25 °C) <br /> 32.3 g/100 mL (100 °C) |
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| SolubleOther = soluble in [[potassium iodide|KI]] solution <br> insoluble in [[ethanol|alcohol]], liquid [[ammonia]], [[nitric acid]] |
| SolubleOther = soluble in [[potassium iodide|KI]] solution <br /> insoluble in [[ethanol|alcohol]], liquid [[ammonia]], [[nitric acid]] |
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| MeltingPtC = 560 |
| MeltingPtC = 560 |
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| MeltingPt_notes = (decomposes) |
| MeltingPt_notes = (decomposes) |
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|Section7={{Chembox Hazards |
|Section7={{Chembox Hazards |
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| ExternalSDS = |
| ExternalSDS = |
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| |
| GHSPictograms = {{GHS03}} {{GHS05}} {{GHS07}} |
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| |
| HPhrases = {{H-phrases|272|302|318}} |
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| PPhrases = {{P-phrases|210|280|301+312+330|305+351+338+310}} |
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| NFPA-H = 2 |
| NFPA-H = 2 |
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| NFPA-F = 0 |
| NFPA-F = 0 |
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}} |
}} |
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|Section8={{Chembox Related |
|Section8={{Chembox Related |
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| OtherAnions = [[Potassium chlorate]]<br/>[[Potassium bromate]] |
| OtherAnions = [[Potassium chlorate]]<br />[[Potassium bromate]] |
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| OtherCations = [[Sodium iodate]] |
| OtherCations = [[Sodium iodate]] |
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| OtherCompounds = [[Potassium iodide]]<br/>[[Potassium periodate]] |
| OtherCompounds = [[Potassium iodide]]<br />[[Potassium periodate]] |
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}} |
}} |
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}} |
}} |
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'''Potassium iodate''' ([[Potassium|K]][[Iodine|I]][[Oxygen|O<sub>3</sub>]]) is |
'''Potassium iodate''' ([[Potassium|K]][[Iodine|I]][[Oxygen|O<sub>3</sub>]]) is an [[ionic compound|ionic]] [[inorganic compound]] with the formula {{chem2|KIO3}}. It is a white salt that is soluble in water.<ref name=":0"/> |
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==Preparation and properties== |
==Preparation and properties== |
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It can be prepared by reacting a potassium-containing base such as [[potassium hydroxide]] with [[iodic acid]], for example:<ref name=":0">{{Cite encyclopedia |title=Iodine and Iodine Compounds |encyclopedia=Ullmann's Encyclopedia of Industrial Chemistry |publisher=Wiley-VCH |location=Weinheim |last1=Lyday |first1=Phyllis A. |editor-last=Ley |editor-first=Claudia |publication-date=26 November 2015 |edition=7th |page=9 |doi=10.1002/14356007.a14_381.pub2 |last2=Kaiho Tatsuo|isbn=9783527306732 }}</ref> |
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Potassium iodate is an [[oxidizing agent]] and as such it can cause fires if in contact with combustible materials or [[reducing agents]]. It can be prepared by reacting a potassium-containing base such as [[potassium hydroxide]] with [[iodic acid]], for example: |
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: |
:[[Iodic acid|HIO<sub>3</sub>]] + [[Potassium hydroxide|KOH]] → KIO<sub>3</sub> + [[Water|H<sub>2</sub>O]] |
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It can also be prepared by adding [[iodine]] to a hot, concentrated solution of potassium hydroxide |
It can also be prepared by adding [[iodine]] to a hot, concentrated solution of potassium hydroxide:<ref name=":0" /> |
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: |
:3 [[iodine|I<sub>2</sub>]] + 6 [[Potassium hydroxide|KOH]] → KIO<sub>3</sub> + 5 [[potassium iodide|KI]] + 3 [[water|H<sub>2</sub>O]] |
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Or by fusing potassium iodide with [[potassium chlorate]], [[potassium bromate|bromate]] or [[potassium perchlorate|perchlorate]], the melt is extracted with water and potassium iodate is isolated from the solution by crystallization:<ref>Pradyot Patnaik. ''Handbook of Inorganic Chemicals''. McGraw-Hill, 2002, {{ISBN|0-07-049439-8}}</ref> |
Or by fusing potassium iodide with [[potassium chlorate]], [[potassium bromate|bromate]] or [[potassium perchlorate|perchlorate]], the melt is extracted with water and potassium iodate is isolated from the solution by crystallization:<ref>Pradyot Patnaik. ''Handbook of Inorganic Chemicals''. McGraw-Hill, 2002, {{ISBN|0-07-049439-8}}</ref> |
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: |
:KI + KClO<sub>3</sub> → KIO<sub>3</sub> + KCl |
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The analogous reaction with [[potassium hypochlorite]] is also possible:<ref>{{Cite journal |last=Andrews |first=Launcelot W. |date=July 1903 |title=Titrations with potassium iodide |url=https://babel.hathitrust.org/cgi/pt?id=uc1.%24b811386&seq=113 |journal=[[Journal of the American Chemical Society]] |location=[[Easton, Pennsylvania]] |publisher=[[US Postal Service]] |volume=25 |issue=7 |page=756 |doi=10.1021/ja02009a012 |via=[[HathiTrust]]}}</ref><blockquote>KI + 3KOCl → 3KCl + KIO<sub>3</sub></blockquote>Conditions/substances to avoid include: [[heat]], [[Shock (mechanics)|shock]], [[friction]],<ref name=":1">{{Cite web |last=Regulatory Affairs |date=23 March 2023 |title=Safety Data Sheet |url=https://www.fishersci.com/store/msds?partNumber=AC418245000&productDescription=POTASSIUM+IODATE%2C+REAGEN+500GR&vendorId=VN00033901&countryCode=US&language=en |url-status=live |archive-url=https://web.archive.org/web/20230922143106/https://www.fishersci.com/store/msds?partNumber=AC418245000&productDescription=POTASSIUM+IODATE%2C+REAGEN+500GR&vendorId=VN00033901&countryCode=US&language=en |archive-date=22 September 2023 |access-date=22 September 2023 |publisher=[[Thermo Fisher Scientific]] |type=Potassium iodate MSDS |publication-place=[[Fair Lawn, NJ]] |edition=5}}</ref> combustible materials,<ref name=":0" /> reducing materials, [[aluminium]],<ref name=":1" /> [[organic compounds]],<ref name=":0" /> [[carbon]], [[hydrogen peroxide]] and [[sulfide]]s.<ref name=":1" /> |
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Conditions/substances to avoid include: [[heat]], [[Shock (mechanics)|shock]], [[friction]], combustible materials, reducing materials, [[aluminium]], [[organic compounds]], [[carbon]], [[hydrogen peroxide]] and [[sulfide]]s. |
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==Applications== |
==Applications== |
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Potassium iodate is sometimes used for iodination of table salt to prevent [[iodine deficiency]]. In the US, [[Iodised salt|iodized salt]] contains [[antioxidant]]s, because [[atmospheric oxygen]] can oxidize [[Aqueous solution|wet]] iodide to iodine; other countries simply use potassium iodate instead.<ref>{{Cite journal |last1=Arroyave |first1=Guillermo |last2=Pineda |first2=Oscar |last3=Scrimshaw |first3=Nevin S. |date=1956 |orig-date=May 1955 |title=The stability of potassium iodate in crude table salt |journal=[[Bulletin of the World Health Organization]] |volume=14 |issue=1 |pages=183–185 |pmid=13329845 |pmc=2538103}}</ref> Salt mixed with [[ferrous fumarate]] and potassium iodate, "double fortified salt", are used to address both iron and iodine deficiencies.<ref>{{cite journal |doi=10.1111/mcn.12773 |title=Improving the lives of millions through new double fortification of salt technology |date=2019 |last1=Diosady |first1=Levente L. |last2=Mannar |first2=M.G. Venkatesh |last3=Krishnaswamy |first3=Kiruba |journal=Maternal & Child Nutrition |volume=15 |issue=Suppl 3 |pages=e12773 |pmid=31148400 |pmc=6594086 }}</ref> Potassium iodate is also used to provide iodine in some [[Infant formula|baby formula]].<ref>{{Cite web |last=James |first=Maia |date=2023-04-04 |title=Best Baby Formula Guide |url=https://gimmethegoodstuff.org/safe-product-guides/safe-infant-formula-guide/ |access-date=2023-09-22 |website=Gimme the Good Stuff |language=en-US}}</ref> |
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Potassium iodate is sometimes used for iodination of table salt to prevent [[iodine deficiency]]. Because iodide can be oxidized to iodine by molecular oxygen under wet conditions, US companies add [[thiosulfate]]s or other [[antioxidant]]s to the potassium iodide. In other countries, potassium iodate is used as a source for dietary iodine. It is also an ingredient in some [[Infant formula|baby formula]] milk. |
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Like [[potassium bromate]], potassium iodate is occasionally used as a [[Flour treatment agent|maturing agent]] in baking. |
Like [[potassium bromate]], potassium iodate is occasionally used as a [[Flour treatment agent|maturing agent]] in baking.<ref>{{Cite encyclopedia |title=Potassium iodate |encyclopedia=BAKERpedia |location=[[Portland, OR]] |url=https://bakerpedia.com/ingredients/potassium-iodate/ |access-date=22 September 2023 |editor-last=Carson |editor-first=Lin}}</ref> |
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===Radiation protection=== |
===Radiation protection=== |
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⚫ | |||
Potassium iodate may be used to protect against accumulation of [[radioiodine|radioactive iodine]] in the [[thyroid]] by saturating the body with a stable source of [[iodine]] prior to exposure.<ref>{{Citation |
Potassium iodate may be used to protect against accumulation of [[radioiodine|radioactive iodine]] in the [[thyroid]] by saturating the body with a stable source of [[iodine]] prior to exposure.<ref>{{Citation |
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| doi = 10.1093/pubmed/21.4.412 |
| doi = 10.1093/pubmed/21.4.412 |
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| pages = 2008–10 |
| pages = 2008–10 |
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| url = http://jpubhealth.oxfordjournals.org/cgi/reprint/21/4/412 |
| url = http://jpubhealth.oxfordjournals.org/cgi/reprint/21/4/412 |
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| archive-url = https://web.archive.org/web/20080905170659/http://jpubhealth.oxfordjournals.org/cgi/reprint/21/4/412 |
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| url-status = dead |
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| archive-date = 2008-09-05 |
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| journal = Journal of Public Health |
| journal = Journal of Public Health |
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| year = 1999 |
| year = 1999 |
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| pmid = 11469363 |
| pmid = 11469363 |
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| doi-access = free |
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}}</ref> Approved by the [[World Health Organization]] for radiation protection, potassium iodate (KIO<sub>3</sub>) is an alternative to [[potassium iodide|potassium iodide (KI)]], which has poor [[shelf life]] in hot and humid [[climate]]s.<ref>{{Citation |
}}</ref> Approved by the [[World Health Organization]] for radiation protection, potassium iodate (KIO<sub>3</sub>) is an alternative to [[potassium iodide|potassium iodide (KI)]], which has poor [[shelf life]] in hot and humid [[climate]]s.<ref>{{Citation |
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| doi = 10.1097/00004032-199311000-00014 |
| doi = 10.1097/00004032-199311000-00014 |
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| last1 = Pahuja | first1 = D.N. |
| last1 = Pahuja | first1 = D.N. |
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| pmid = 8225995 |
| pmid = 8225995 |
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| journal = Health |
| journal = Health Physics |
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}}</ref> The [[UK]], [[Singapore]], [[United Arab Emirates]], and the [[U.S. state]]s [[Idaho]] and [[Utah]] |
}}</ref> The [[UK]], [[Singapore]], [[United Arab Emirates]], and the [[U.S. state]]s [[Idaho]] and [[Utah]] all maintain potassium iodate [[Tablet (pharmacy)|tablets]] towards this end.{{Citation needed|date=February 2010}} Following the [[September 11 attacks]], the government of [[Republic of Ireland|Ireland]] issued potassium iodate tablets to all households for a similar purpose.<ref name="dohc">{{cite web |url=http://www.dohc.ie/press/releases/2008/20080403c.html |title=Decision to Discontinue the Future Distribution of Iodine Tablets |access-date=2013-05-22 |url-status=dead |archive-url=https://web.archive.org/web/20131018013248/http://www.dohc.ie/press/releases/2008/20080403c.html |archive-date=2013-10-18 }}</ref> |
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{| class="wikitable" style="margin-left: auto; margin-right: auto; border: none;" |
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⚫ | |||
A scenario that upon later expert Irish examination in 2007, was found to not have justified their distribution.<ref>{{cite web |url=http://www.rpii.ie/Site/Media/Press-Releases/Radioactivity-released-from-Wylfa-nuclear-power-pl.aspx |title=Archived copy |accessdate=2013-04-08 |url-status=dead |archiveurl=https://web.archive.org/web/20131017221002/http://www.rpii.ie/Site/Media/Press-Releases/Radioactivity-released-from-Wylfa-nuclear-power-pl.aspx |archivedate=2013-10-17 }}</ref><ref name="dohc" /> The Irish government now upon realizing their error suggests that the tablets be disposed of with municipal waste.<ref name="dohc" />]] |
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{| class="wikitable" |
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|+ Recommended Dosage for Radiological Emergencies involving radioactive iodine<ref>{{Citation |
|+ Recommended Dosage for Radiological Emergencies involving radioactive iodine<ref>{{Citation |
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| |
| date = 1999 |
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| title = Guidelines for Iodine Prophylaxis following Nuclear Accidents |
| title = Guidelines for Iodine Prophylaxis following Nuclear Accidents |
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| publication-place = |
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| place = Geneva |
| place = Geneva |
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| publisher = [[World Health Organization]] |
| publisher = [[World Health Organization]] |
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| url = |
| url =https://www.who.int/ionizing_radiation/pub_meet/Iodine_Prophylaxis_guide.pdf |
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}}</ref> |
}}</ref> |
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! Age |
! Age |
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| 21 |
| 21 |
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Potassium iodate is not approved by the [[Food and Drug Administration (United States)|U.S. Food and Drug Administration]] (FDA) for use as a [[thyroid blocker]], and the FDA has taken action against US websites that promote this use.<ref>{{Cite web|url=http://www.nukepills.com/potassium-iodate-vs-potassium-iodide.html|title=Potassium iodide vs potassium iodate. Which one works?}}</ref><ref>{{cite web|url=http://www.nukepills.com/docs/Potassium%20Iodate%20warning%20letter.pdf|title=Potassium Iodate Warning Letter|author=W. Charles Becoat|publisher=Food and Drug Administration|date=29 May 2003}}</ref> |
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==Safety== |
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Potassium iodate is an [[oxidizing agent]] and as such it can form explosive mixtures when combined with organic compounds.<ref name=":0"/> |
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{{clear}} |
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==References== |
==References== |
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{{refimprove|date=January 2009}} |
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{{reflist}} |
{{reflist}} |
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{{Potassium compounds}} |
{{Potassium compounds}} |
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{{Iodates}} |
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[[Category:Iodates]] |
[[Category:Iodates]] |
Latest revision as of 10:30, 18 April 2024
Names | |
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IUPAC name
Potassium iodate
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Other names
Iodic acid, potassium salt
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.028.938 |
EC Number |
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E number | E917 (glazing agents, ...) |
PubChem CID
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RTECS number |
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
KIO3 | |
Molar mass | 214.001 g/mol |
Appearance | white crystalline powder |
Odor | odorless |
Density | 3.89 g/cm3 |
Melting point | 560 °C (1,040 °F; 833 K) (decomposes) |
4.74 g/100 mL (0 °C) 9.16 g/100 mL (25 °C) 32.3 g/100 mL (100 °C) | |
Solubility | soluble in KI solution insoluble in alcohol, liquid ammonia, nitric acid |
−63.1·10−6 cm3/mol | |
Hazards | |
GHS labelling: | |
H272, H302, H318 | |
P210, P280, P301+P312+P330, P305+P351+P338+P310 | |
NFPA 704 (fire diamond) | |
Flash point | Non-flammable |
Related compounds | |
Other anions
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Potassium chlorate Potassium bromate |
Other cations
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Sodium iodate |
Related compounds
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Potassium iodide Potassium periodate |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Potassium iodate (KIO3) is an ionic inorganic compound with the formula KIO3. It is a white salt that is soluble in water.[1]
Preparation and properties
[edit]It can be prepared by reacting a potassium-containing base such as potassium hydroxide with iodic acid, for example:[1]
It can also be prepared by adding iodine to a hot, concentrated solution of potassium hydroxide:[1]
Or by fusing potassium iodide with potassium chlorate, bromate or perchlorate, the melt is extracted with water and potassium iodate is isolated from the solution by crystallization:[2]
- KI + KClO3 → KIO3 + KCl
The analogous reaction with potassium hypochlorite is also possible:[3]
KI + 3KOCl → 3KCl + KIO3
Conditions/substances to avoid include: heat, shock, friction,[4] combustible materials,[1] reducing materials, aluminium,[4] organic compounds,[1] carbon, hydrogen peroxide and sulfides.[4]
Applications
[edit]Potassium iodate is sometimes used for iodination of table salt to prevent iodine deficiency. In the US, iodized salt contains antioxidants, because atmospheric oxygen can oxidize wet iodide to iodine; other countries simply use potassium iodate instead.[5] Salt mixed with ferrous fumarate and potassium iodate, "double fortified salt", are used to address both iron and iodine deficiencies.[6] Potassium iodate is also used to provide iodine in some baby formula.[7]
Like potassium bromate, potassium iodate is occasionally used as a maturing agent in baking.[8]
Radiation protection
[edit]Potassium iodate may be used to protect against accumulation of radioactive iodine in the thyroid by saturating the body with a stable source of iodine prior to exposure.[9] Approved by the World Health Organization for radiation protection, potassium iodate (KIO3) is an alternative to potassium iodide (KI), which has poor shelf life in hot and humid climates.[10] The UK, Singapore, United Arab Emirates, and the U.S. states Idaho and Utah all maintain potassium iodate tablets towards this end.[citation needed] Following the September 11 attacks, the government of Ireland issued potassium iodate tablets to all households for a similar purpose.[11]
Age | KI in mg | KIO3 in mg |
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Over 12 years old | 130 | 170 |
3 – 12 years old | 65 | 85 |
1 – 36 months old | 32 | 42 |
< 1 month old | 16 | 21 |
Potassium iodate is not approved by the U.S. Food and Drug Administration (FDA) for use as a thyroid blocker, and the FDA has taken action against US websites that promote this use.[13][14]
Safety
[edit]Potassium iodate is an oxidizing agent and as such it can form explosive mixtures when combined with organic compounds.[1]
References
[edit]- ^ a b c d e f Lyday, Phyllis A.; Kaiho Tatsuo (26 November 2015). "Iodine and Iodine Compounds". In Ley, Claudia (ed.). Ullmann's Encyclopedia of Industrial Chemistry (7th ed.). Weinheim: Wiley-VCH. p. 9. doi:10.1002/14356007.a14_381.pub2. ISBN 9783527306732.
- ^ Pradyot Patnaik. Handbook of Inorganic Chemicals. McGraw-Hill, 2002, ISBN 0-07-049439-8
- ^ Andrews, Launcelot W. (July 1903). "Titrations with potassium iodide". Journal of the American Chemical Society. 25 (7). Easton, Pennsylvania: US Postal Service: 756. doi:10.1021/ja02009a012 – via HathiTrust.
- ^ a b c Regulatory Affairs (23 March 2023). "Safety Data Sheet" (Potassium iodate MSDS) (5 ed.). Fair Lawn, NJ: Thermo Fisher Scientific. Archived from the original on 22 September 2023. Retrieved 22 September 2023.
- ^ Arroyave, Guillermo; Pineda, Oscar; Scrimshaw, Nevin S. (1956) [May 1955]. "The stability of potassium iodate in crude table salt". Bulletin of the World Health Organization. 14 (1): 183–185. PMC 2538103. PMID 13329845.
- ^ Diosady, Levente L.; Mannar, M.G. Venkatesh; Krishnaswamy, Kiruba (2019). "Improving the lives of millions through new double fortification of salt technology". Maternal & Child Nutrition. 15 (Suppl 3): e12773. doi:10.1111/mcn.12773. PMC 6594086. PMID 31148400.
- ^ James, Maia (2023-04-04). "Best Baby Formula Guide". Gimme the Good Stuff. Retrieved 2023-09-22.
- ^ Carson, Lin (ed.). "Potassium iodate". BAKERpedia. Portland, OR. Retrieved 22 September 2023.
- ^ Astbury, John; Horsley, Stephen; Gent, Nick (1999), "Evaluation of a scheme for the pre-distribution of stable iodine (potassium iodate) to the civilian population residing within the immediate countermeasures zone of a nuclear submarine construction facility", Journal of Public Health, 21 (4): 2008–10, doi:10.1093/pubmed/21.4.412, PMID 11469363, archived from the original on 2008-09-05
- ^ Pahuja, D.N.; Rajan, M.G.; Borkar, A.V.; Samuel, A.M. (Nov 2008), "Potassium iodate and its comparison to potassium iodide as a blocker of 131I uptake by the thyroid in rats", Health Physics, 65 (5): 545–9, doi:10.1097/00004032-199311000-00014, PMID 8225995
- ^ "Decision to Discontinue the Future Distribution of Iodine Tablets". Archived from the original on 2013-10-18. Retrieved 2013-05-22.
- ^ Guidelines for Iodine Prophylaxis following Nuclear Accidents (PDF), Geneva: World Health Organization, 1999
- ^ "Potassium iodide vs potassium iodate. Which one works?".
- ^ W. Charles Becoat (29 May 2003). "Potassium Iodate Warning Letter" (PDF). Food and Drug Administration.