Melite may refer to:
- Melite (ancient city), an ancient Punic-Roman city located on Malta, or a Greco-Roman reference to the island on which the city was located
- Melite (Attica), one of the demes of ancient Attica
- Melite, ancient name of Lake Trichonida in Greece
- Melite (Greek mythology)
- Melite (heroine)
- Melite (naiad)