Hammes is a surname. Notable people with the surname include:
- Charles-Léon Hammes (1898–1967), Luxembourgian lawyer, judge and the third President of the European Court of Justice
- Ernie Hammes (born 1968), Luxembourg trumpeter who specializes in jazz but also plays classical music
- George Albert Hammes (1911–1993), the eighth Roman Catholic Bishop of the Diocese of Superior, Wisconsin from 1960 to 1985
- Gordon Hammes (born 1934), emeritus professor of biochemistry at Duke University and member of the United States National Academy of Sciences
- Hammes Company (or Hammes Co.), healthcare consulting firm
- Liselotte Hammes (born 1933), German operatic soprano and academic voice teacher
- Thomas Hammes, retired U.S. Marine officer and specialist in counter-insurgency warfare