117 results found
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells

    Daniela Ávila-González, Wendy Portillo ... Néstor F Díaz
    Interaction of human embryonic stem cells (hESC) with human amniotic epithelial cells (hAEC) confers hESC a pluripotent potential that resembles the anteriorized epiblast, which is predisposed to form the neural ectoderm.
    1. Developmental Biology

    Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes

    Dorit Hockman, Alan J Burns ... Clare V H Baker
    Embryonic fate-mapping approaches in zebrafish, Xenopus and lamprey illuminate the evolutionary origins of carotid body glomus cells and pulmonary neuroendocrine cells.
    1. Evolutionary Biology

    New light shed on the early evolution of limb-bone growth plate and bone marrow

    Jordi Estefa, Paul Tafforeau ... Sophie Sanchez
    A three-dimensional investigation of extinct-tetrapod limbs shows that even though bone elongation and blood-cell production are intimately related to mammal long bones, these functions actually appeared successively in tetrapod evolution.
    1. Developmental Biology

    Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

    Weiyi Tang, Megan L Martik ... Marianne E Bronner
    Lineage analysis reveals that cardiac neural crest contributes to cardiomyocytes across vertebrates and consistent with this, the neural crest gene regulatory program is reactivated upon heart regeneration in zebrafish.
    1. Developmental Biology
    2. Evolutionary Biology

    Evolution of the head-trunk interface in tetrapod vertebrates

    Elizabeth M Sefton, Bhart-Anjan S Bhullar ... James Hanken
    Both gill musculature and the evolutionarily conserved cucullaris muscle are derived from unsegmented mesoderm adjacent to the first 3 somites, extending the posterior limit of cranial mesoderm.
    1. Evolutionary Biology

    Evolution: Unraveling the history of limb bones

    Holly N Woodward
    Ancient fossils give clues as to when features of modern tetrapod bones emerged.
    Version of Record
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    1. Developmental Biology
    2. Evolutionary Biology
    Silhoutte of a coqui frog in black on a purple background.

    The Natural History of Model Organisms: The big potential of the small frog Eleutherodactylus coqui

    Sarah E Westrick, Mara Laslo, Eva K Fischer
    The coquí frog is of interest to researchers in fields as diverse as development biology, social behavior and the biology of invasive species.
    1. Developmental Biology
    2. Evolutionary Biology

    Characterization of the finch embryo supports evolutionary conservation of the naive stage of development in amniotes

    Siu-Shan Mak, Cantas Alev ... Raj K Ladher
    Finch embryos are laid at an earlier stage than other avian embryos and contain cells with similar properties to pluripotent embryonic stem cells from mice.
    1. Developmental Biology
    2. Evolutionary Biology

    Wnt/β-catenin regulates an ancient signaling network during zebrafish scale development

    Andrew J Aman, Alexis N Fulbright, David M Parichy
    Zebrafish scales depend on interactions among Wnt, Ectodysplasin and Hedgehog signaling pathways similar to those underlying feathers, teeth and hair follicles, suggesting a deep homology of ectodermal appendages in vertebrates.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Temporally resolved early bone morphogenetic protein-driven transcriptional cascade during human amnion specification

    Nikola Sekulovski, Jenna C Wettstein ... Kenichiro Taniguchi
    Analyses of transcriptomic dynamics in a new model of human amnion formation identify five continuous amniogenic transcriptional phases as well as a critical role of TFAP2A in amnion fate progression.

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