Insights

Insight articles are related to original research papers in eLife and explain why the results reported in the paper are significant in a given field of research. Insight articles are commissioned by eLife staff.

Latest articles

    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Vaccines: How do adjuvants enhance immune responses?

    Rekha R Rapaka
    By altering which peptide antigens are presented to CD4+ T cells, adjuvants affect the specificity of the immune response.
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    1. Neuroscience

    Serial Dependence: Connecting past and present

    Sihan Yang, Anastasia Kiyonaga
    A neural signature of serial dependence has been found, which mirrors the attractive bias of visual information seen in behavioral experiments.
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    1. Neuroscience

    Vision: Running into differences

    Eleni Psarou, Shivangi Patel, Marieke Schölvinck
    Body movement does not significantly increase neuronal activity in the primary visual cortex of marmosets, in contrast to the effects observed in mice.
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    1. Cancer Biology
    2. Cell Biology

    Cancer: Modeling glioblastoma

    Ian Lorimer
    Establishing a zebrafish model of a deadly type of brain tumor highlights the role of the immune system in the early stages of the disease.
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    1. Neuroscience

    Cerebellum: Linking abnormal neural activity patterns to motor deficits

    David J Herzfeld
    Abnormal activity in the cerebellar nuclei can be used to predict motor symptoms and induce them experimentally, pointing to potential therapeutic strategies.
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    1. Neuroscience

    Spatial Attention: Time to get deep

    Max Schulz, Malte Wöstmann
    Asymmetries in the size of structures deep below the cortex explain how alpha oscillations in the brain respond to shifts in attention.
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    1. Stem Cells and Regenerative Medicine

    Hematopoiesis: Counting blood precursors

    Sarah Duchamp de Chastaigne, Catherine M Sawai
    A new mathematical model can estimate the number of precursor cells that contribute to regenerating blood cells in mice.
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    1. Neuroscience

    Neural Plasticity: Restoring cerebellar-dependent learning

    Jessica L Verpeut
    Behavioral and pharmaceutical interventions reverse defects associated with increased cerebellar long-term depression in a mouse model of Fragile X syndrome.
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    1. Neuroscience

    Decision Making: Unraveling the enigmatic role of the subthalamic nucleus

    Qianli Yang
    Subpopulations of neurons in the subthalamic nucleus have distinct activity patterns that relate to the three hypotheses of the Drift Diffusion Model.
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    1. Neuroscience

    Connectomes: Mapping the fly nerve cord

    Anna Seggewisse, Michael Winding
    The first neuronal wiring diagram of an insect nerve cord, which includes biological information on cell type and organisation, enables further investigation into premotor circuit function.
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