DDT

DDT
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4Q3F, 3KAN, 1DPT
Dynodwyr
Cyfenwau	DDT, DDCT, D-dopachrome tautomerase, MIF-2, MIF2, D-DT
Dynodwyr allanol	OMIM: 602750 HomoloGene: 1038 GeneCards: DDT
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • dopachrome isomerase activity • D-dopachrome decarboxylase activity • lyase activity • GO:0005145 cytokine receptor binding • phenylpyruvate tautomerase activity Cydrannau o'r gell • cytoplasm • extracellular exosome • extracellular space Prosesau biolegol • melanin biosynthetic process • negative regulation of macrophage chemotaxis • positive regulation of tumor necrosis factor production • positive regulation of inflammatory response • positive regulation of ERK1 and ERK2 cascade Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1652	n/a
Ensembl	ENSG00000099977 ENSG00000275003	n/a
UniProt	P30046	n/a
RefSeq (mRNA)	NM_001084392 NM_001355 NM_001381852 NM_001397485	n/a
RefSeq (protein)	NP_001077861 NP_001346 NP_001368781	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DDT yw DDT a elwir hefyd yn D-dopachrome tautomerase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DDT.

• DDCT

Llyfryddiaeth

• "D-dopachrome tautomerase promotes IL-6 expression and inhibits adipogenesis in preadipocytes. ". Cytokine. 2012. PMID 22951300.
• "The action of D-dopachrome tautomerase as an adipokine in adipocyte lipid metabolism. ". PLoS One. 2012. PMID 22428043.
• "UVB-induced inflammation gives increased d-dopachrome tautomerase activity in blister fluid which correlates with macrophage migration inhibitory factor. ". Exp Dermatol. 2003. PMID 12823441.
• "D-dopachrome tautomerase is over-expressed in pancreatic ductal adenocarcinoma and acts cooperatively with macrophage migration inhibitory factor to promote cancer growth. ". Int J Cancer. 2016. PMID 27434219.
• "The clinical significance of the MIF homolog d-dopachrome tautomerase (MIF-2) and its circulating receptor (sCD74) in burn.". Burns. 2016. PMID 27209369.