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COMPET: High resolution high sensitivity MRI compatible pre-clinical PET scanner
/ Hines, Kim-Eigard (U. Oslo (main)) ; Bolle, Erlend (U. Oslo (main)) ; Skretting, Arne (Rikshosp Radiumhosp Med. Ctr., Oslo) ; Rohne, Ole (U. Oslo (main)) ; Bjaalie, Jan G (CMBN, Oslo) ; Volgyes, David (U. Oslo (main)) ; Rissi, Michael (U. Oslo (main)) ; Dorholt, Ole (U. Oslo (main)) ; Stapnes, Steinar (U. Oslo (main) ; CERN)
COMPET is a pre-clinical MRI compatible PET scanner which decouples sensitivity and resolution by the use of a novel detector design. The detector has been built using 8 x 8 cm(2) square layers consisting of 30 LYSO crystals (2 x 3 x 80 mm(2)) interleaved with 24 Wavelength Shifting Fibers (WLS) (3 x 1 x 80 mm(3)). [...]
2013
- Published in : Nucl. Instrum. Methods Phys. Res., A 732 (2013) 581-585
In : 13th Vienna Conference on Instrumentation, Vienna, Austria, 11 - 15 Feb 2013, pp.581-585
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Characterization of a high resolution and high sensitivity pre-clinical PET scanner with 3D event reconstruction
/ Rissi, M (Oslo U.) ; Bjaalie, J G (Oslo U. ; CMBN, Oslo) ; Bolle, E (Oslo U.) ; Dorholt, O (Oslo U.) ; Hines, K E (Oslo U.) ; Rohne, O (Oslo U.) ; Skretting, A (Oslo U.) ; Stapnes, S (Oslo U. ; CERN) ; Volgyes, D (Oslo U.)
COMPET is a preclinical PET scanner aiming towards a high sensitivity, a high resolution and MRI compatibility by implementing a novel detector geometry. In this approach, long scintillating LYSO crystals are used to absorb the gamma-rays. [...]
2012
- Published in : Nucl. Instrum. Methods Phys. Res., A 695 (2012) 135-138
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INSIDE in-beam positron emission tomography system for particle range monitoring in hadrontherapy
/ Bisogni, Maria Giuseppina (U. Pisa (main)) ; Attili, Andrea (U. Turin (main)) ; Battistoni, Giuseppe (INFN, Italy) ; Belcari, Nicola (U. Pisa (main)) ; Camarlinghi, Niccoló (U. Pisa (main)) ; Cerello, Piergiorgio (INFN, Italy) ; Coli, Silvia (INFN, Italy) ; Del Guerra, Alberto (U. Pisa (main)) ; Ferrari, Alfredo (CERN) ; Ferrero, Veronica (U. Turin (main)) et al.
The quality assurance of particle therapy treatment is a fundamental issue that can be addressed by developing reliable monitoring techniques and indicators of the treatment plan correctness. Among the available imaging techniques, positron emission tomography (PET) has long been investigated and then clinically applied to proton and carbon beams. [...]
2016 - 12 p.
- Published in : Journal of Medical Imaging 4 (2016) 011005
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An overview of recent developments in FLUKA PET tools
/ Augusto, R S (CERN ; LMU Munich (main)) ; Bauer, J (Heidelberg U. Hospital) ; Bouhali, O (Texas A&M; U. Qatar, Doha) ; Cuccagna, C (CERN ; TERA, Novara ; U. Geneva (main)) ; Gianoli, C (LMU Munich (main)) ; Kozłowska, W S (CERN ; Med. U. of Vienna, Spitalgasse) ; Ortega, P G (U. Salamanca (main)) ; Tessonnier, T (Centre François Baclesse, Caen) ; Toufique, Y (Texas A&M; U. Qatar, Doha ; Hassan 1st U., Settat) ; Vlachoudis, V (CERN) et al.
The new developments of the FLUKA Positron-Emission-Tomography (PET) tools are detailed. FLUKA is a fully integrated Monte Carlo (MC) particle transport code, used for an extended range of applications, including Medical Physics. [...]
2018
- Published in : Physica Medica 54 (2018) 189-199
Fulltext: PDF;
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Improving depth-of-interaction resolution in pixellated PET detectors using neural networks
/ Zatcepin, Artem (Tech. U., Munich (main) ; LMU Munich (main)) ; Pizzichemi, Marco (CERN) ; Polesel, Andrea (CERN ; Milan Bicocca U.) ; Paganoni, Marco (Milan Bicocca U.) ; Auffray, Etiennette (CERN) ; Ziegler, Sibylle I (Tech. U., Munich (main) ; LMU Munich (main)) ; Omidvari, Negar (Tech. U., Munich (main) ; UC, Davis (main))
Parallax error is a common issue in high-resolution preclinical positron emission tomography (PET) scanners as well as in clinical scanners that have a long axial field of view (FOV), which increases estimation uncertainty of the annihilation position and therefore degrades the spatial resolution. A way to address this issue is depth-of-interaction (DOI) estimation. [...]
2020 - 11 p.
- Published in : Phys. Med. Biol. 65 (2020) 175017
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Feasibility study for a biomedical experimental facility based on LEIR at CERN
/ Abler, Daniel (CERN ; Oxford U.) ; Garonna, Adriano (CERN) ; Carli, Christian (CERN) ; Dosanjh, Manjit (CERN) ; Peach, Ken (CERN ; Oxford U.) ; Orecchia, Roberto (Istituto Europeo di Oncologia, Milano ; CNAO, Pavia)
In light of the recent European developments in ion beam therapy, there is a strong interest from the biomedical research community to have more access to clinically relevant beams. Beamtime for pre-clinical studies is currently very limited and a new dedicated facility would allow extensive research into the radiobiological mechanisms of ion beam radiation and the development of more refined techniques of dosimetry and imaging. [...]
2013
- Published in : J. Radiat. Res. 54 (2013) i162-i167
Oxford Univ. Press Open Access article: PDF;
In : PARTNER, pp.i162-i167
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Fulltext
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SiPM applications in positron emission tomography: toward ultimate PET time-of-flight resolution
/ Lecoq, P (CERN ; Valencia, Polytechnic U.) ; Gundacker, S (CERN ; U. Milan (main) ; RWTH Aachen U.)
The development of PET/MRI multimodality, requiring magnetic field immunity of the photodetectors associated with an increased demand for time-of-flight capabilities with a strong impact on effective PET sensitivity and image quality, has pushed the medical imaging community to progressively replace photomultipliers, traditionally used in PET scanners, by solid-state photodetectors, avalanche diodes (APD) and silicon photomultipliers (SiPM). Recent years have seen spectacular progresses in the performances of SiPMs, in terms of photodetection efficiency (PDE), noise and cross talk reduction, timing performance, etc., not mentioning their availability in a large variety of dimensions and packages, as single photodetectors, but also linear arrays and matrices of different sizes [...]
2021
- Published in : Eur. Phys. J. Plus 136 (2021) 292
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