NIP30

NIP30
Identifikatori
Aliasi	PSME3IP1
Vanjski ID-jevi	OMIM: 617766 MGI: 1919637 HomoloGene: 11797 GeneCards: PSME3IP1
Lokacija gena (čovjek)
Hrom.	Hromosom 16 (čovjek)
Kraj	57,186,116 bp
Lokacija gena (miš)
Hrom.	Hromosom 8 (miš)
Kraj	95,328,625 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• jedro;
Biološki proces	• negative regulation of protein binding; • negative regulation of proteasomal protein catabolic process;
	Izvori:Amigo / QuickGO
Ortolozi
	80011
	102122
	ENSG00000172775
	ENSMUSG00000031774
	Q9GZU8
	Q91WE2
NM_024946; NM_001354078; NM_001354079; NM_001354080; NM_001354081;
	NM_001354082; NM_001354083; NM_001354084; NM_001354085; NM_001354086; NM_001354088; NM_001354090; NM_001354091; NM_001354092; NM_001354094; NM_001354097; NM_001354098; NM_001354099; NM_001354100; NM_001354087; NM_001354089; NM_001354095; NM_001354096; NM_001354101; NM_001354102; NM_001354103
	NM_028221; NM_001363456; NM_001363457
NP_079222; NP_001341007; NP_001341008; NP_001341009; NP_001341010;
	NP_001341011; NP_001341012; NP_001341013; NP_001341014; NP_001341015; NP_001341017; NP_001341019; NP_001341020; NP_001341021; NP_001341023; NP_001341026; NP_001341027; NP_001341028; NP_001341029; NP_001341016; NP_001341018; NP_001341024; NP_001341025; NP_001341030; NP_001341031; NP_001341032
	NP_082497; NP_001350385; NP_001350386
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein NIP30 je protein koji je kod ljudi kodiran genom FAM192A.^[5]^[6]

Gross (2017) mapirao je gen FAM192A u ludski hromosom 16q13 na osnovu poravnanja sekvence FAM192A (GenBank BC020536) sa genomskom sekvencom (GRCh38). Waddell et al. (2016) mapirali su gen Fam192a u mišji hromosom 8.^[7]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 254 aminokiselina, a molekulska težina 28.912 Da.^[8].

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10	20	30	40	50
MDGGDDGNLI	IKKRFVSEAE	LDERRKRRQE	EWEKVRKPED	PEECPEEVYD
PRSLYERLQE	QKDRKQQEYE	EQFKFKNMVR	GLDEDETNFL	DEVSRQQELI
EKQRREEELK	ELKEYRNNLK	KVGISQENKK	EVEKKLTVKP	IETKNKFSQA
KLLAGAVKHK	SSESGNSVKR	LKPDPEPDDK	NQEPSSCKSL	GNTSLSGPSI
HCPSAAVCIG	ILPGLGAYSG	SSDSESSSDS	EGTINATGKI	VSSIFRTNTF
LEAP

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172775 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031774 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
^ "Entrez Gene: NIP30 NEFA-interacting nuclear protein NIP30".
^ Waddell, D. S., Duffin, P. J., Haddock, A. N., Triplett, V. E., Saredy, J. J., Kakareka, K. M., Eldredge, J. T. Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RNG finger and SPRY domain containing 1 in skeletal muscle. Gene 576: 319-332, 2016. PubMed: 26497270
^ "UniProt, Q9GZU8". Pristupljeno 8. 7. 2021.

Dopunska literatura

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000172775 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031774 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: NIP30 NEFA-interacting nuclear protein NIP30".

[7] Waddell, D. S., Duffin, P. J., Haddock, A. N., Triplett, V. E., Saredy, J. J., Kakareka, K. M., Eldredge, J. T. Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RNG finger and SPRY domain containing 1 in skeletal muscle. Gene 576: 319-332, 2016. PubMed: 26497270

[UniProt-8] "UniProt, Q9GZU8". Pristupljeno 8. 7. 2021.

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