Protein 2 sličan endotelinskom receptoru B jest protein koji je kod ljudi kodiran genom GPR37L1 sa hromosoma 1.[5][6]

GPR37L1
Identifikatori
AliasiGPR37L1
Vanjski ID-jeviOMIM: 617630 MGI: 1928503 HomoloGene: 3500 GeneCards: GPR37L1
Lokacija gena (čovjek)
Hromosom 1 (čovjek)
Hrom.Hromosom 1 (čovjek)[1]
Hromosom 1 (čovjek)
Genomska lokacija za GPR37L1
Genomska lokacija za GPR37L1
Bend1q32.1Početak202,122,886 bp[1]
Kraj202,133,592 bp[1]
Lokacija gena (miš)
Hromosom 1 (miš)
Hrom.Hromosom 1 (miš)[2]
Hromosom 1 (miš)
Genomska lokacija za GPR37L1
Genomska lokacija za GPR37L1
Bend1|1 E4Početak135,087,972 bp[2]
Kraj135,095,419 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija peptide binding
G protein-coupled peptide receptor activity
GO:0001948, GO:0016582 vezivanje za proteine
G protein-coupled receptor activity
signal transducer activity
prosaposin receptor activity
Ćelijska komponenta integral component of membrane
ćelijska membrana
receptor complex
membrana
projekcija ćelije
ciliary membrane
Biološki proces positive regulation of cerebellar granule cell precursor proliferation
negative regulation of astrocyte differentiation
negative regulation of hydrogen peroxide-induced cell death
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
negative regulation of neuron differentiation
negative regulation of smoothened signaling pathway
positive regulation of MAPK cascade
GO:0072468 Transdukcija signala
G protein-coupled receptor signaling pathway
negative regulation of systemic arterial blood pressure
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_004767

NM_134438

RefSeq (bjelančevina)

NP_004758

NP_602320

Lokacija (UCSC)Chr 1: 202.12 – 202.13 MbChr 1: 135.09 – 135.1 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 481 aminokiselina, a molekulska težina 52.771 Da.[7]

1020304050
MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTED
EEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQ
ELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLS
VMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGD
VSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILA
KLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYS
LVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKH
EQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLI
NQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANG
SDNKLKTEVSSSIYFHKPRESPPLLPLGTPC

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170075 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026424 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Valdenaire O, Giller T, Breu V, Ardati A, Schweizer A, Richards JG (Apr 1998). "A new family of orphan G protein-coupled receptors predominantly expressed in the brain". FEBS Lett. 424 (3): 193–6. doi:10.1016/S0014-5793(98)00170-7. PMID 9539149. S2CID 7999925.
  6. ^ "Entrez Gene: GPR37L1 G protein-coupled receptor 37 like 1".
  7. ^ "UniProt, O60883" (jezik: en.). Pristupljeno 12. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura

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Vanjski linkovi

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Šablon:G-protein spregnuti receptor Šablon:Transmembranski receptori