Protein FAM107A jest protein koji je kod ljudi kodiran genom FAM107A sa hromosoma 3.[5][6][7]

FAM107A
Identifikatori
AliasiFAM107A
Vanjski ID-jeviOMIM: 608295 MGI: 3041256 HomoloGene: 48509 GeneCards: FAM107A
Lokacija gena (čovjek)
Hromosom 3 (čovjek)
Hrom.Hromosom 3 (čovjek)[1]
Hromosom 3 (čovjek)
Genomska lokacija za FAM107A
Genomska lokacija za FAM107A
Bend3p14.3-p14.2Početak58,564,117 bp[1]
Kraj58,627,610 bp[1]
Lokacija gena (miš)
Hromosom 14 (miš)
Hrom.Hromosom 14 (miš)[2]
Hromosom 14 (miš)
Genomska lokacija za FAM107A
Genomska lokacija za FAM107A
Bend14|14 A1Početak14,151,750 bp[2]
Kraj14,173,499 bp[2]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
molekularna funkcija
actin binding
Ćelijska komponenta neuron projection
jedro
nuclear speck
stress fiber
citoplazma
focal adhesion
actin cytoskeleton
ruffle membrane
sinapsa
citoskelet
ćelijska membrana
membrana
međućelijske veze
projekcija ćelije
Biološki proces regulation of growth
regulation of cell growth
actin filament polymerization
positive regulation of cell migration
positive regulation of protein ubiquitination
regulation of protein stability
cellular response to nutrient levels
regulation of actin cytoskeleton organization
kognitivna funkcija
actin filament bundle assembly
negative regulation of focal adhesion assembly
regulation of microtubule cytoskeleton organization
cellular response to glucocorticoid stimulus
negative regulation of long-term synaptic potentiation
GO:1990376 negative regulation of G1/S transition of mitotic cell cycle
ćelijski ciklus
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001076778
NM_001282713
NM_001282714
NM_007177

NM_183187
NM_001360337
NM_001360338
NM_001360339

RefSeq (bjelančevina)

NP_001070246
NP_001269642
NP_001269643
NP_009108
NP_001269643.1

NP_001347266
NP_001347267
NP_001347268
NP_899010

Lokacija (UCSC)Chr 3: 58.56 – 58.63 MbChr 14: 14.15 – 14.17 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 144 aminokiseline, а molekulska težina 17.455 Da.[8]

1020304050
MYSEIQRERADIGGLMARPEYREWNPELIKPKKLLNPVKASRSHQELHRE
LLMNHRRGLGVDSKPELQRVLEHRRRNQLIKKKKEELEAKRLQCPFEQEL
LRRQQRLNQLEKPPEKEEDHAPEFIKVRENLRRIATLTSEEREL

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168309 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021750 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Wang L, Darling J, Zhang JS, Liu W, Qian J, Bostwick D, Hartmann L, Jenkins R, Bardenhauer W, Schutte J, Opalka B, Smith DI (Feb 2000). "Loss of expression of the DRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinoma". Genes Chromosomes Cancer. 27 (1): 1–10. doi:10.1002/(SICI)1098-2264(200001)27:1<1::AID-GCC1>3.0.CO;2-6. PMID 10564580.
  6. ^ Yamato T, Orikasa K, Fukushige S, Orikasa S, Horii A (Apr 2000). "Isolation and characterization of the novel gene, TU3A, in a commonly deleted region on 3p14.3→p14.2 in renal cell carcinoma". Cytogenet Cell Genet. 87 (3–4): 291–5. doi:10.1159/000015452. PMID 10702698. S2CID 34558356.
  7. ^ "Entrez Gene: FAM107A family with sequence similarity 107, member A".
  8. ^ "UniProt, O95990" (jezik: engleski). Pristupljeno 3. 11. 2021.

Dopunska literatura

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