Protein SGT1 ie protein koji je kod ljudi kodoran genom ECD.[5][6][7]

ECD
Identifikatori
AliasiECD
Vanjski ID-jeviOMIM: 616464 MGI: 1917851 HomoloGene: 5256 GeneCards: ECD
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za ECD
Genomska lokacija za ECD
Bend10q22.2Početak73,130,155 bp[1]
Kraj73,169,055 bp[1]
Lokacija gena (miš)
Hromosom 14 (miš)
Hrom.Hromosom 14 (miš)[2]
Hromosom 14 (miš)
Genomska lokacija za ECD
Genomska lokacija za ECD
Bend14|14 A3Početak20,369,920 bp[2]
Kraj20,398,189 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001105 transcription coactivator activity
GO:0001948, GO:0016582 vezivanje za proteine
histone acetyltransferase binding
Ćelijska komponenta citoplazma
jedro
nukleoplazma
R2TP complex
citosol
Biološki proces regulation of G1/S transition of mitotic cell cycle
Ćelijska proliferacija
GO:0009373 regulation of transcription, DNA-templated
transcription by RNA polymerase II
transcription, DNA-templated
regulation of glycolytic process
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
Prerada RNK
mRNA processing
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001135752
NM_001135753
NM_007265

NM_027475

RefSeq (bjelančevina)

NP_001129224
NP_001129225
NP_009196

NP_081751

Lokacija (UCSC)Chr 10: 73.13 – 73.17 MbChr 14: 20.37 – 20.4 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 644 aminokiseline, а molekulska težina 72.758.[8]

1020304050
MEETMKLATMEDTVEYCLFLIPDESRDSDKHKEILQKYIERIITRFAPML
VPYIWQNQPFNLKYKPGKGGVPAHMFGVTKFGDNIEDEWFIVYVIKQITK
EFPELVARIEDNDGEFLLIEAADFLPKWLDPENSTNRVFFCHGELCIIPA
PRKSGAESWLPTTPPTIPQALNIITAHSEKILASESIRAAVNRRIRGYPE
KIQASLHRAHCFLPAGIVAVLKQRPRLVAAAVQAFYLRDPIDLRACRVFK
TFLPETRIMTSVTFTKCLYAQLVQQRFVPDRRSGYRLPPPSDPQYRAHEL
GMKLAHGFEILCSKCSPHFSDCKKSLVTASPLWASFLESLKKNDYFKGLI
EGSAQYRERLEMAENYFQLSVDWPESSLAMSPGEEILTLLQTIPFDIEDL
KKEAANLPPEDDDQWLDLSPDQLDQLLQEAVGKKESESVSKEEKEQNYDL
TEVSESMKAFISKVSTHKGAELPREPSEAPITFDADSFLNYFDKILGPRP
NESDSDDLDDEDFECLDSDDDLDFETHEPGEEASLKGTLDNLKSYMAQMD
QELAHTCISKSFTTRNQVEPVSQTTDNNSDEEDSGTGESVMAPVDVDLNL
VSNILESYSSQAGLAGPASNLLQSMGVQLPDNTDHRPTSKPTKN

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122882 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021810 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet. 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932. S2CID 28511451.
  6. ^ Gaziova I, Bonnette PC, Henrich VC, Jindra M (maj 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development. 131 (11): 2715–25. doi:10.1242/dev.01143. PMID 15128659.
  7. ^ "Entrez Gene: ECD ecdysoneless homolog (Drosophila)".
  8. ^ "UniProt, O95905". Pristupljeno 1. 9. 2021.

Dopunska literatura

uredi