Arsenit metiltransferaza je enzim koji je kod ljudi kodiran genom AS3MT.[5][6]

AS3MT
Identifikatori
AliasiAS3MT
Vanjski ID-jeviOMIM: 611806 MGI: 1929882 HomoloGene: 10754 GeneCards: AS3MT
Lokacija gena (čovjek)
Hromosom 10 (čovjek)
Hrom.Hromosom 10 (čovjek)[1]
Hromosom 10 (čovjek)
Genomska lokacija za AS3MT
Genomska lokacija za AS3MT
Bend10q24.32Početak102,869,470 bp[1]
Kraj102,901,899 bp[1]
Lokacija gena (miš)
Hromosom 19 (miš)
Hrom.Hromosom 19 (miš)[2]
Hromosom 19 (miš)
Genomska lokacija za AS3MT
Genomska lokacija za AS3MT
Bend19|19 C3Početak46,695,897 bp[2]
Kraj46,729,538 bp[2]
Ontologija gena
Molekularna funkcija GO:0102674, GO:0102675 methyltransferase activity
aktivnost sa transferazom
methylarsonite methyltransferase activity
arsenite methyltransferase activity
Ćelijska komponenta citosol
citoplazma
Biološki proces toxin metabolic process
arsonoacetate metabolic process
Metilacija
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_020682

NM_020577

RefSeq (bjelančevina)

NP_065733

NP_065602

Lokacija (UCSC)Chr 10: 102.87 – 102.9 MbChr 19: 46.7 – 46.73 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca proteina je 375 aminokiselina, a molekulska težina 41.748[7]

1020304050
MAALRDAEIQKDVQTYYGQVLKRSADLQTNGCVTTARPVPKHIREALQNV
HEEVALRYYGCGLVIPEHLENCWILDLGSGSGRDCYVLSQLVGEKGHVTG
IDMTKGQVEVAEKYLDYHMEKYGFQASNVTFIHGYIEKLGEAGIKNESHD
IVVSNCVINLVPDKQQVLQEAYRVLKHGGELYFSDVYTSLELPEEIRTHK
VLWGECLGGALYWKELAVLAQKIGFCPPRLVTANLITIQNKELERVIGDC
RFVSATFRLFKHSKTGPTKRCQVIYNGGITGHEKELMFDANFTFKEGEIV
EVDEETAAILKNSRFAQDFLIRPIGEKLPTSGGCSALELKDIITDPFKLA
EESDSMKSRCVPDAAGGCCGTKKSC

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000214435 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003559 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lin S, Shi Q, Nix FB, Styblo M, Beck MA, Herbin-Davis KM, Hall LL, Simeonsson JB, Thomas DJ (mart 2002). "A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol". The Journal of Biological Chemistry. 277 (13): 10795–803. doi:10.1074/jbc.M110246200. PMID 11790780.
  6. ^ "Entrez Gene: AS3MT arsenic (+3 oxidation state) methyltransferase".
  7. ^ "UniProt, Q9HBK9". Pristupljeno 30. 8. 2021.

Dopunska literatura

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Vanjski linkovi

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Šablon:Jednougljične transferaze