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SiPM applications in positron emission tomography: toward ultimate PET time-of-flight resolution
/ Lecoq, P (CERN ; Valencia, Polytechnic U.) ; Gundacker, S (CERN ; U. Milan (main) ; RWTH Aachen U.)
The development of PET/MRI multimodality, requiring magnetic field immunity of the photodetectors associated with an increased demand for time-of-flight capabilities with a strong impact on effective PET sensitivity and image quality, has pushed the medical imaging community to progressively replace photomultipliers, traditionally used in PET scanners, by solid-state photodetectors, avalanche diodes (APD) and silicon photomultipliers (SiPM). Recent years have seen spectacular progresses in the performances of SiPMs, in terms of photodetection efficiency (PDE), noise and cross talk reduction, timing performance, etc., not mentioning their availability in a large variety of dimensions and packages, as single photodetectors, but also linear arrays and matrices of different sizes [...]
2021
- Published in : Eur. Phys. J. Plus 136 (2021) 292
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A Systematic Study to Optimize SiPM Photo-Detectors for Highest Time Resolution in PET
/ Gundacker, S. (CERN) ; Auffray, E. (CERN) ; Frisch, B. (CERN) ; Hillemanns, H. (CERN) ; Jarron, P. (INFN, Turin) ; Meyer, T. (CERN) ; Pauwels, K. (CERN) ; Lecoq, P. (CERN)
We report on a systematic study of time resolution made with three different commercial silicon photomultipliers (SiPMs) (Hamamatsu MPPC S10931-025P, S10931-050P, and S10931-100P) and two LSO scintillating crystals. This study aimed to determine the optimum detector conditions for highest time resolution in a prospective time-of-flight positron emission tomography (TOF-PET) system. [...]
2012
- Published in : IEEE Trans. Nucl. Sci. 59 (2012) 1798-1804
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Enhancing timing performance of heterostructures with double-sided readout
/ Pagano, Fiammetta (CERN ; Milan Bicocca U. ; Valencia, Polytechnic U.) ; Kratochwil, Nicolaus (CERN ; UC, Davis) ; Lowis, Carsten (CERN ; RWTH Aachen U.) ; Choong, Woon-Seng (LBNL, Berkeley) ; Paganoni, Marco (CERN ; Milan Bicocca U.) ; Pizzichemi, Marco (CERN ; Milan Bicocca U.) ; Cates, Joshua W (LBNL, Berkeley) ; Auffray, Etiennette (CERN)
Objective. Heterostructured scintillators offer a promising solution to balance the sensitivity and timing in TOF-PET detectors. [...]
2024 - 13 p.
- Published in : Phys. Med. Biol. 69 (2024) 205012
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DOI estimation through signal arrival time distribution: a theoretical description including proof of concept measurements
/ Loignon-Houle, Francis (Sherbrooke U.) ; Gundacker, Stefan (CERN ; Milan Bicocca U.) ; Toussaint, Maxime (Sherbrooke U.) ; Camirand Lemyre, Félix (Toronto U., Math. Dept.) ; Auffray, Etiennette (CERN) ; Fontaine, Réjean (Sherbrooke U. ; IPP, Canada) ; Charlebois, Serge A (Sherbrooke U. ; IPP, Canada) ; Lecoq, Paul (CERN ; GACE-ICMUV) ; Lecomte, Roger (Sherbrooke U.)
The challenge to reach 10 ps coincidence time resolution (CTR) in time-of-flight positron emission tomography (TOF-PET) is triggering major efforts worldwide, but timing improvements of scintillation detectors will remain elusive without depth-of-interaction (DOI) correction in long crystals. Nonetheless, this momentum opportunely brings up the prospect of a fully time-based DOI estimation since fast timing signals intrinsically carry DOI information, even with a traditional single-ended readout. [...]
2021 - 19 p.
- Published in : Phys. Med. Biol. 66 (2021) 095015
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Vacuum ultraviolet silicon photomultipliers applied to BaF$_2$ cross-luminescence detection for high-rate ultrafast timing applications
/ Gundacker, S (CERN ; Milan Bicocca U.) ; Pots, R H (CERN ; Aachen, Tech. Hochsch.) ; Nepomnyashchikh, A (Irkutsk State U.) ; Radzhabov, E (Irkutsk State U.) ; Shendrik, R (Irkutsk State U.) ; Omelkov, S (Tartu, Inst. Phys.) ; Kirm, M (Tartu, Inst. Phys.) ; Acerbi, F (Fond. Bruno Kessler, Povo) ; Capasso, M (Fond. Bruno Kessler, Povo) ; Paternoster, G (Fond. Bruno Kessler, Povo) et al.
Inorganic scintillators are widely used for fast timing applications in high-energy physics (HEP) experiments, time-of-flight positron emission tomography and time tagging of soft and hard x-ray photons at advanced light sources. As the best coincidence time resolution (CTR) achievable is proportional to the square root of the scintillation decay time it is worth studying fast cross-luminescence, for example in BaF2 which has an intrinsic yield of about 1400 photons/MeV. [...]
2021 - 18 p.
- Published in : Phys. Med. Biol. 66 (2021) 114002
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On the way to the 10 ps time-of-flight PET challenge
/ Lecoq, P (CERN)
There is a consensus for gathering the multidisciplinary academic and industrial medical imaging community around the ambitious challenge to develop a 10 ps Time-of-Flight PET scanner (TOFPET). The goal is to reduce the radiation dose (currently 5–25 mSv for whole-body PET/CT) and/or scan time (currently > 10 min) by an order of magnitude, with a significant gain in the patient comfort and cost per exam (currently in the range of 1000 € per scan). [...]
2022 - 7 p.
- Published in : Eur. Phys. J. Plus 137 (2022) 964
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Fast28 a low-power fast readout design for SiPMs in 28nm CMOS
/ Piller, M (CERN ; Graz, Tech. U.) ; Ballabriga, R (CERN) ; Bandi, F (CERN) ; Campbell, M (CERN) ; Deutschmann, B (Graz, Tech. U.) ; Fernández-Tenllado, J M (CERN) ; Gascon, D (Barcelona U.) ; Gomez, S (Barcelona, Polytechnic U. ; Barcelona U.) ; Michalowska-Forsyth, A (Graz, Tech. U.) ; Mauricio, J (Barcelona U.) et al.
The field of detector readout electronics for precise timing has experienced a remarkable surge of interest due to its diverse range of applications in nuclear medicine such as Positron Emission Tomography (PET), High Energy Physics (HEP), Time-of-Flight (ToF) mass spectrometry and many other fields. This growth can be attributed to rapid advancements in photodetectors, particularly the silicon photomultiplier (SiPM), which has demonstrated exceptional suitability for these applications, owing to its ability to generate signals with unprecedentedly fast rise times. [...]
2023 - 1 p.
- Published in : 10.1109/NSSMICRTSD49126.2023.10337864
In : 2023 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector (RTSD) Conference (2023 IEEE NSS MIC RTSD), Vancouver, Canada, 4 - 11 Nov 2023
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Design considerations for a new generation of SiPMs with unprecedented timing resolution
/ Enoch, S. (Fresnel Inst., Marseille) ; Gola, A. (Fond. Bruno Kessler, Trento) ; Lecoq, P. (CERN ; Valencia, Polytechnic U.) ; Rivetti, A. (Turin U.)
The potential of photon detectors to achieve precise timing information is of increasing importance in many domains, PET and CT scanners in medical imaging and particle physics detectors, amongst others. The goal to increase by an order of magnitude the sensitivity of PET scanners and to deliver, via time-of-flight (TOF), true space points for each event, as well as the constraints set by future particle accelerators require a further leap in time resolution of scintillator-based ionizing radiation detectors, reaching eventually a few picoseconds resolution for sub MeV energy deposits. [...]
arXiv:2101.02952.-
2021-02-12 - 16 p.
- Published in : JINST 16 (2021) P02019
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