CERN Accelerating science

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1.
Active dosimetry for VHEE FLASH radiotherapy using beam profile monitors and charge measurements / Rieker, Vilde F (CERN ; Oslo U.) ; Corsini, Roberto (CERN) ; Stapnes, Steinar (CERN) ; Adli, Erik (Oslo U.) ; Farabolini, Wilfrid (CERN) ; Grilj, Veljko (SUBATECH, Nantes) ; Sjobak, Kyrre N (Oslo U.) ; Wroe, Laurence M (CERN) ; Aksoy, Avni (CERN ; Ankara U.) ; Robertson, Cameron S (Oxford U.) et al.
The discovery of the FLASH effect has revealed a high potential for treating cancer more efficiently by sparing healthy tissue. The surge in related medical research activities over the last couple of years has triggered a demand for technology with the capability of generating and measuring ionizing radiation at ultra-high doserates (UHDR). [...]
2024 - 12 p. - Published in : Nucl. Instrum. Methods Phys. Res., A 1069 (2024) 169845 Fulltext: PDF;
2.
Comparative Analysis of Radiotherapy Linear Accelerator Downtime and Failure Modes in the UK, Nigeria and Botswana / Wroe, Laurence M. (Oxford U.) ; Ige, Taofeeq A. ; Asogwa, Obinna C. ; Aruah, Simeon C. (Unlisted, NG) ; Grover, Surbhi (Botswana U.) ; Makufa, Remigio (Botswana U.) ; Fitz-Gibbon, Matthew (U. Oxford (main)) ; Coleman, N. (Unlisted, US, DC) ; Dosanjh, M. (Oxford U. ; CERN) ; Van den Heuvel, F. (Unlisted, UK ; U. Oxford (main)) et al.
The lack of radiotherapy linear accelerators (LINACs) in Low- and Middle- Income Countries (LMICs) has been recognised as a major barrier to providing quality cancer care in these regions, along with a shortfall in the number of highly qualified personnel. It is expected that additional challenges will be faced in operating precise, high tech radiotherapy equipment in these environments, and anecdotal evidence suggests that LINACs have greater downtime and higher failure rates of components than their counterparts in High-Income Countries. [...]
arXiv:1905.03447.- 2020-03-01 - 8 p. - Published in : Clinical Oncology: 32 (2020) , pp. e111-e118
- Published in : Clinical Oncology: 35 (2023) , no. 5, pp. e347 Fulltext: 1905.03447 - PDF; Publication - PDF; Erratum - PDF;
3.
Minimising Transverse Multipoles in Accelerating RF Cavities via Azimuthally Modulated Designs / Wroe, Laurence (JAI, UK) ; Apsimon, Robert (Lancaster U. (main)) ; Dosanjh, Manjit (CERN) ; Sheehy, Suzanne (Melbourne U.)
In this paper, we build upon previous work of designing RF structures that support modes with tailored multipolar fields by applying the concept to negate the transverse multipoles in accelerating RF cavities caused by the incorporation of waveguide slots and tuning deformations. We outline a systematic method for designing structures that minimise these transverse multipoles and present analysis of simulations of two different minimisation designs..
2022 - 4 p. - Published in : JACoW IPAC 2022 (2022) 610-613 Fulltext: PDF;
In : 13th International Particle Accelerator Conference (IPAC 2022), Bangkok, Thailand, 12 - 17 Jun 2022, pp.610-613
4.
Creating Exact Multipolar Fields in Accelerating RF Cavities via an Azimuthally Modulated Design / Wroe, Laurence M (JAI, UK) ; Apsimon, Robert J (Cockcroft Inst. Accel. Sci. Tech.) ; Dosanjh, Manjit (JAI, UK ; CERN) ; Sheehy, Suzanne L (JAI, UK ; Melbourne U.)
In this paper, we present a novel method for designing RF structures with specifically tailored multipolar field contributions. This has a range of applications, including the suppression of unwanted multipolar fields or the introduction of wanted terms, such as for quadrupole focusing. [...]
Geneva : JACoW, 2021 - 4 p. - Published in : JACoW IPAC 2021 (2021) 1154-1157 Fulltext: PDF;
In : 12th International Particle Accelerator Conference (IPAC 2021), Online, 24 - 28 May 2021, pp.1154-1157
5.
Abstract D066: A prospective study on chemotherapy-induced anemia using serial hemoglobin measurement in cancer patients undergoing treatment at National Hospital Abuja, Nigeria / Aruah, Simeon Chinedu (NMC, Abuja) ; Oyesegun, Rasaq (NMC, Abuja) ; Ogbe, Oche (NMC, Abuja) ; Ezikeanyi, Sampson (NMC, Abuja) ; Aniwada, Elias (Enugu State U. Sci. Tech.) ; Dosanjh, Manjit (CERN) ; Wroe, Laurence (Oxford U.) ; Coleman, Norman (Int. Cancer Expert Corps. Inc., Washington)
Anaemia is a common complication of myelo-suppressive chemotherapy. Severe anaemia is usually treated with red blood cell transfusion, however, mild-to-moderate anaemia are most often managed conservatively. [...]
2020 - Published in : Cancer Epidemiology, Biomarkers & Prevention 29 (2020) D066
6.
A Design for a 3 TeV Rapid Cycling Synchrotron for Muon Acceleration in the SPS Tunnel / Dascalau, Titus
Current proposals for new high-energy physics machines either focus on building ever-larger circular hadron colliders, such as the proposed FCC- hh, or on electron-positron linac designs, such as CLIC and ILC [...]
2020. - 107 p. (JAI Graduate Accelerator Physics Programme - student design projects ; 2020)


10.17181/CERN.YA66.G3H6

See also: similar author names
1 Wroe, L M
2 Wroe, Laurence M
1 Wroe, Laurence M.
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