產熱素

產熱素
識別號
别名	UCP1；, SLC25A7, UCP, uncoupling protein 1
外部ID	OMIM：113730 MGI：98894 HomoloGene：22524 GeneCards：UCP1
基因位置（人类）
染色体	4號染色體
终止	140,568,961 bp
基因位置（小鼠）
染色体	小鼠8号染色体
终止	84,025,081 bp
RNA表达模式
	查阅更多表达数据
基因本體
分子功能	• transmembrane transporter activity; • purine ribonucleotide binding; • long-chain fatty acid binding; • cardiolipin binding; • oxidative phosphorylation uncoupler activity;
細胞組分	• mitochondrial envelope; • 膜; • 線粒體; • mitochondrial membranes; • mitochondrial inner membrane; • integral component of membrane;
生物學過程	• regulation of transcription by RNA polymerase II; • brown fat cell differentiation; • diet induced thermogenesis; • ion transport; • response to temperature stimulus; • response to nutrient levels; • cellular response to hormone stimulus; • cellular response to reactive oxygen species; • cellular response to fatty acid; • regulation of reactive oxygen species biosynthetic process; • response to cold; • mitochondrial transmembrane transport; • adaptive thermogenesis; • mitochondrial transport; • proton transmembrane transport; • positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
直系同源
	7350
	22227
	ENSG00000109424
	ENSMUSG00000031710
	P25874
	P12242
	NM_021833
	NM_009463
	NP_068605
	NP_033489
	維基數據
檢視/編輯人類	檢視/編輯小鼠

產熱素（Thermogenin），被發現者稱為解偶聯蛋白，現在稱為解偶聯蛋白1（UCP1）^[5]是在棕色脂肪組織（BAT）線粒體中發現的解偶聯蛋白。它用於通過不發抖的生熱（英语：Thermogenesis）來產生熱量，並且在定量上對抵抗嬰兒的熱量損失做出了重要的貢獻，否則由於高表面積-體積比，會發生熱量損失。

參考資料

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000109424 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000031710 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Entrez Gene: UCP1 uncoupling protein 1 (mitochondrial, proton carrier). （原始内容存档于2018-10-23）.

外部連結

Seaweed anti-obesity tablet hope （页面存档备份，存于互联网档案馆） (BBC - Thermogenin mentioned as part of process)
醫學主題詞表（MeSH）：thermogenin

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[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000109424 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000031710 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Entrez Gene: UCP1 uncoupling protein 1 (mitochondrial, proton carrier). （原始内容存档于2018-10-23）.

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