romidepsin (Q7363205)

Romidepsin (English)

3 October 2016

C₂₄H₃₆N₄O₆S₂

1 reference

Romidepsin (English)

18 November 2016

CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C

1 reference

Romidepsin (English)

18 November 2016

C/C=C\1/C(=O)N[C@H](C(=O)O[C@H]\2CC(=O)N[C@@H](C(=O)N[C@H](CSSCC/C=C2)C(=O)N1)C(C)C)C(C)C

1 reference

European Medicines Agency product number

Romidepsin (English)

18 November 2016

1 reference

EMEA/H/C/002122

reference URL

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/002122/human_med_001590.jsp

World Health Organisation international non-proprietary name

22 March 2017

romidepsin (English)

1 reference

Chromobacterium violaceum

romidepsin (English)

3 October 2016

2 references

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

Characterization of a gene cluster responsible for the biosynthesis of anticancer agent FK228 in Chromobacterium violaceum No. 968

Humicola fuscoatra

1 reference

Study of marine natural products including resorcyclic acid lactones from Humicola fuscoatra that reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells

medical condition treated

1 reference

lung small cell carcinoma

17 August 2016

1 reference

human immunodeficiency virus infectious disease

17 August 2016

1 reference

Drug Indications Extracted from FAERS

17 August 2016

1 reference

mature T-cell and NK-cell lymphoma

2 October 2018

1 reference

Drug Indications Extracted from FAERS

2 October 2018

mycosis fungoides

1 reference

Drug Indications Extracted from FAERS

physically interacts with

2 October 2018

histone deacetylase 1

1 reference

17 August 2016

histone deacetylase 2

1 reference

17 August 2016

Histone deacetylase 3

1 reference

17 August 2016

Histone deacetylase 4

1 reference

17 August 2016

Histone deacetylase 5

1 reference

17 August 2016

Histone deacetylase 6

1 reference

17 August 2016

Histone deacetylase 7

1 reference

17 August 2016

Histone deacetylase 8

1 reference

17 August 2016

Histone deacetylase 9

1 reference

imported from Wikimedia project

17 August 2016

pregnancy category

US pregnancy category D

1 reference

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category C

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Romidepsin

last update

25 September 2020

antineoplastic antibiotics

1 reference

Institute for Safe Medication Practices

Medical Subject Headings

15 March 2018

romiDEPsin

subject named as

romidepsin

1 reference

reference URL

https://www.ismp.org/recommendations/tall-man-letters-list

InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1

2 September 2022

Commons category

Romidepsin

0 references

Identifiers

InChI

1 reference

Romidepsin (English)

18 November 2016

2 references

Romidepsin (English)

18 November 2016

ChEBI release 2020-09-01

CAS Registry Number

128517-07-7

1 reference

romidepsin (English)

18 November 2016

1 reference

Romidepsin (English)

18 November 2016

2 references

Romidepsin (English)

18 November 2016

Reaxys registry number

6854221

1 reference

romidepsin (English)

3 October 2016

mapping relation type

2 references

DEPSIPEPTIDE (English)

18 November 2016

International Chemical Identifier

InChI

InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1

1 reference

DEPSIPEPTIDE (English)

18 November 2016

2 references

inferred from InChIKey

DSSTOX compound identifier

1 reference

0 references

0 references

0 references

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.211.884

27 December 2018

ECHA Substance Infocard ID

(1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pe (English)

quotation

CAS no.: 128517-07-7 (English)

100.211.884

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.211.884

27 December 2018

(1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pe (English)

quotation

CAS no.: 128517-07-7 (English)

ATC code

L01XX39

0 references

1 reference

romidepsin (English)

18 November 2016

1 reference

Medical Subject Headings

14 March 2018

1 reference

romidepsin (English)

18 November 2016

1 reference

2 references

romidepsin (English)

18 November 2016

Natural Product Atlas ID

NPA016792

2 references

based on heuristic

inferred from InChIKey

MedlinePlus drug identifier

0 references

1 reference

romidepsin (English)

18 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

romidepsin (English)

3 October 2016

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C1527027

1 reference