Alzheimer's disease (Q11081)

10.1016/J.JALZ.2018.02.018

3 July 2018

30 November 2020

aging-associated disease

2 references

DOI

DOI

10.1016/J.PNEUROBIO.2014.02.004

disease

0 references

image

Auguste D aus Marktbreit.jpg
360 × 451; 165 KB

1 reference

Dutch Wikipedia

pronunciation audio

LL-Q33810 (ori)-Psubhashish-ଆଲଜିମର ରୋଗ.wav
1.7 s; 155 KB

Odia

1 reference

https://lingualibre.org/wiki/Q636487

named after

Alois Alzheimer

1 reference

Wikimedia import URL

https://en.wikipedia.org/wiki/Alzheimer's_disease

spoken text audio

Nl-Ziekte van Alzheimer-article.ogg
23 min 14 s; 15.36 MB

Dutch

1 reference

https://nl.wikipedia.org/w/index.php?title=Ziekte_van_Alzheimer&oldid=54621523

Dutch Wikipedia

Wikimedia import URL

Alzheimer's Disease.ogg
46 min 24 s; 17.67 MB

English

0 references

Hy-Ալցհայմերի հիվանդություն (Alzheimer's disease).ogg
4 min 48 s; 8.29 MB

0 references

0 references

1 reference

memory loss that disrupts daily life

symptoms and signs

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

confusion with time and space

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

challenges in planning or solving problems

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

difficulty completing familiar tasks at home, at work or at leisure

0 references

trouble understanding visual images and spatial relationships

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

decreased or poor judgment

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

withdrawal from work or social activities

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

problems with words in speaking or writing

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

changes in mood and personality

0 references

misplacing things and losing the ability to retrace steps

1 reference

http://www.alz.org/fr/10-signes-et-symptomes-d-alzheimer.asp

dementia

1 reference

neurological diagnostic techniques

medical examination

1 reference

medical history

1 reference

magnetic resonance imaging

1 reference

object class of occurrence

psychological test

0 references

genetic testing

Amyloid beta precursor protein

2 references

https://www.alzheimers.org.uk/about-dementia/genetic-testing-kits

https://www.nia.nih.gov/health/alzheimers-causes-and-risk-factors/alzheimers-disease-genetics-fact-sheet

possible treatment

memantine

1 reference

donepezil

1 reference

rivastigmine

1 reference

galantamine

1 reference

https://cs.wikipedia.org/w/index.php?title=Fysostigmin&oldid=20310449

1 reference

drug or therapy used for treatment

quetiapine

1 reference

2 October 2018

aripiprazole

1 reference

2 October 2018

galantamine

2 references

2 October 2018

donepezil

1 reference

2 October 2018

risperidone

1 reference

2 October 2018

memantine

1 reference

2 October 2018

rivastigmine

1 reference

Food and Drug Administration

2 October 2018

6 July 2007

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/PKI06M3IW0

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020823s035,021025s023lbl.pdf

memantine

start time

16 October 2003

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/W8O17SJF3T

http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021487s010s012s014,021627s008lbl.pdf

pyritinol

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

https://drugs.ncats.io/drug/AK5Q5FZH2R

http://rupharma.com/encephabol/

genetic association

APOE

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=348

http://www.genome.gov/gwastudies/index.cfm?gene=APOE

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

25 May 2020

NKAIN2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=154215

http://www.genome.gov/gwastudies/index.cfm?gene=NKAIN2

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

BMPER

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=168667

http://www.genome.gov/gwastudies/index.cfm?gene=BMPER

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

25 May 2020

SLC8A1-AS1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=100128590

http://www.genome.gov/gwastudies/index.cfm?gene=SLC8A1-AS1

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

25 May 2020

MS4A3

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=932

http://www.genome.gov/gwastudies/index.cfm?gene=MS4A3

Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.

25 May 2020

CR1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=1378

http://www.genome.gov/gwastudies/index.cfm?gene=CR1

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

CD2AP

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=23607

http://www.genome.gov/gwastudies/index.cfm?gene=CD2AP

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

ABCA7

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=10347

http://www.genome.gov/gwastudies/index.cfm?gene=ABCA7

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

INPP5D

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=3635

http://www.genome.gov/gwastudies/index.cfm?gene=INPP5D

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

ZCWPW1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=55063

http://www.genome.gov/gwastudies/index.cfm?gene=ZCWPW1

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

CELF1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=10658

http://www.genome.gov/gwastudies/index.cfm?gene=CELF1

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

FERMT2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=10979

http://www.genome.gov/gwastudies/index.cfm?gene=FERMT2

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

CASS4

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=57091

http://www.genome.gov/gwastudies/index.cfm?gene=CASS4

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

PTK2B

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=2185

http://www.genome.gov/gwastudies/index.cfm?gene=PTK2B

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

SORL1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=6653

http://www.genome.gov/gwastudies/index.cfm?gene=SORL1

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

SQSTM1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=8878

http://www.genome.gov/gwastudies/index.cfm?gene=SQSTM1

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

NDUFAF6

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=137682

http://www.genome.gov/gwastudies/index.cfm?gene=NDUFAF6

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

18 February 2020

AP2A2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=161

http://www.genome.gov/gwastudies/index.cfm?gene=AP2A2

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

IGH

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=3492

http://www.genome.gov/gwastudies/index.cfm?gene=IGH

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

SPPL2A

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=84888

http://www.genome.gov/gwastudies/index.cfm?gene=SPPL2A

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

TRIP4

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=9325

http://www.genome.gov/gwastudies/index.cfm?gene=TRIP4

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

CD33

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=945

http://www.genome.gov/gwastudies/index.cfm?gene=CD33

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

25 May 2020

GLIS3

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=169792

http://www.genome.gov/gwastudies/index.cfm?gene=GLIS3

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

25 May 2020

PRRC2C

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=23215

http://www.genome.gov/gwastudies/index.cfm?gene=PRRC2C

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

FMN2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=56776

http://www.genome.gov/gwastudies/index.cfm?gene=FMN2

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

CTNNA2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=1496

http://www.genome.gov/gwastudies/index.cfm?gene=CTNNA2

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

LIMS2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=55679

http://www.genome.gov/gwastudies/index.cfm?gene=LIMS2

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

MOBP

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=4336

http://www.genome.gov/gwastudies/index.cfm?gene=MOBP

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

STK32B

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=55351

http://www.genome.gov/gwastudies/index.cfm?gene=STK32B

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

AFF1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=4299

http://www.genome.gov/gwastudies/index.cfm?gene=AFF1

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

ANKRD55

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=79722

http://www.genome.gov/gwastudies/index.cfm?gene=ANKRD55

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

CAMK4

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=814

http://www.genome.gov/gwastudies/index.cfm?gene=CAMK4

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

DMXL1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=1657

http://www.genome.gov/gwastudies/index.cfm?gene=DMXL1

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

MEGF10

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=84466

http://www.genome.gov/gwastudies/index.cfm?gene=MEGF10

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

SAP30L

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=79685

http://www.genome.gov/gwastudies/index.cfm?gene=SAP30L

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

PLEKHG1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=57480

http://www.genome.gov/gwastudies/index.cfm?gene=PLEKHG1

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

CYCS

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=54205

http://www.genome.gov/gwastudies/index.cfm?gene=CYCS

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

ELMO1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=9844

http://www.genome.gov/gwastudies/index.cfm?gene=ELMO1

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

HECW1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=23072

http://www.genome.gov/gwastudies/index.cfm?gene=HECW1

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

EXOC4

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=60412

http://www.genome.gov/gwastudies/index.cfm?gene=EXOC4

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

CSMD1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=64478

http://www.genome.gov/gwastudies/index.cfm?gene=CSMD1

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

ST18

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=9705

http://www.genome.gov/gwastudies/index.cfm?gene=ST18

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

18 February 2020

NCS1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=23413

http://www.genome.gov/gwastudies/index.cfm?gene=NCS1

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

PLPP4

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=196051

http://www.genome.gov/gwastudies/index.cfm?gene=PPAPDC1A

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

ARHGAP20

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=57569

http://www.genome.gov/gwastudies/index.cfm?gene=ARHGAP20

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

SLC4A8

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=9498

http://www.genome.gov/gwastudies/index.cfm?gene=SLC4A8

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

CRADD

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=8738

http://www.genome.gov/gwastudies/index.cfm?gene=CRADD

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

ANO4

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=121601

http://www.genome.gov/gwastudies/index.cfm?gene=ANO4

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

GPC6

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=10082

http://www.genome.gov/gwastudies/index.cfm?gene=GPC6

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

MYO16

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=23026

http://www.genome.gov/gwastudies/index.cfm?gene=MYO16

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

CLMN

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=79789

http://www.genome.gov/gwastudies/index.cfm?gene=CLMN

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

GABRG3

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=2567

http://www.genome.gov/gwastudies/index.cfm?gene=GABRG3

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

VAT1L

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=57687

http://www.genome.gov/gwastudies/index.cfm?gene=VAT1L

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

CACNA1G

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=8913

http://www.genome.gov/gwastudies/index.cfm?gene=CACNA1G

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

BCAS3

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=54828

http://www.genome.gov/gwastudies/index.cfm?gene=BCAS3

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

PPIAP59

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=390956

http://www.genome.gov/gwastudies/index.cfm?gene=LOC390956

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

TGM6

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=343641

http://www.genome.gov/gwastudies/index.cfm?gene=TGM6

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

PARVB

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=29780

http://www.genome.gov/gwastudies/index.cfm?gene=PARVB

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

25 May 2020

APOC1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=341

http://www.genome.gov/gwastudies/index.cfm?gene=APOC1

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

25 May 2020

NECTIN2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=5819

http://www.genome.gov/gwastudies/index.cfm?gene=PVRL2

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

25 May 2020

TOMM40

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=10452

http://www.genome.gov/gwastudies/index.cfm?gene=TOMM40

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

25 May 2020

TREM2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=54209

http://www.genome.gov/gwastudies/index.cfm?gene=TREM2

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

25 May 2020

MPZL1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=9019

http://www.genome.gov/gwastudies/index.cfm?gene=MPZL1

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

25 May 2020

ATXN7L1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=222255

http://www.genome.gov/gwastudies/index.cfm?gene=ATXN7L1

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

25 May 2020

LUZP2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=338645

http://www.genome.gov/gwastudies/index.cfm?gene=LUZP2

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

25 May 2020

CDON

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=50937

http://www.genome.gov/gwastudies/index.cfm?gene=CDON

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

25 May 2020

PCNX1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=22990

http://www.genome.gov/gwastudies/index.cfm?gene=PCNX

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

25 May 2020

PICALM

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=8301

http://www.genome.gov/gwastudies/index.cfm?gene=PICALM

Genome-wide association study of Alzheimer's disease

25 May 2020

PPP1R3B

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=79660

http://www.genome.gov/gwastudies/index.cfm?gene=PPP1R3B

Genome-wide association study of Alzheimer's disease

25 May 2020

SLC4A1AP

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=22950

http://www.genome.gov/gwastudies/index.cfm?gene=SLC4A1AP

A comprehensive genetic association study of Alzheimer disease in African Americans

25 May 2020

POLN

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=353497

http://www.genome.gov/gwastudies/index.cfm?gene=POLN

A comprehensive genetic association study of Alzheimer disease in African Americans

25 May 2020

CNTNAP2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=26047

http://www.genome.gov/gwastudies/index.cfm?gene=CNTNAP2

A comprehensive genetic association study of Alzheimer disease in African Americans

25 May 2020

STK24

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=8428

http://www.genome.gov/gwastudies/index.cfm?gene=STK24

A comprehensive genetic association study of Alzheimer disease in African Americans

25 May 2020

VSNL1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=7447

http://www.genome.gov/gwastudies/index.cfm?gene=VSNL1

Genome-wide association study of Alzheimer's disease with psychotic symptoms

25 May 2020

BIN1

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=274

http://www.genome.gov/gwastudies/index.cfm?gene=BIN1

Genome-wide association study of Alzheimer's disease with psychotic symptoms

25 May 2020

MPP7

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=143098

http://www.genome.gov/gwastudies/index.cfm?gene=MPP7

Genome-wide association study of Alzheimer's disease with psychotic symptoms

25 May 2020

ZNF320

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=162967

http://www.genome.gov/gwastudies/index.cfm?gene=ZNF320

Genome-wide association study of Alzheimer's disease with psychotic symptoms

25 May 2020

STK11

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=6794

http://www.genome.gov/gwastudies/index.cfm?gene=STK11

Genome-wide association study of Alzheimer's disease with psychotic symptoms

25 May 2020

DIP2C

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=22982

http://www.genome.gov/gwastudies/index.cfm?gene=DIP2C

Genome-wide association study of Alzheimer's disease with psychotic symptoms

25 May 2020

DCHS2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=54798

http://www.genome.gov/gwastudies/index.cfm?gene=DCHS2

Genome-wide association analysis of age-at-onset in Alzheimer's disease

25 May 2020

CLU

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=1191

http://www.genome.gov/gwastudies/index.cfm?gene=CLU

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

25 May 2020

CCDC134

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=79879

http://www.genome.gov/gwastudies/index.cfm?gene=CCDC134

Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort

25 May 2020

MTHFD1L

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=25902

http://www.genome.gov/gwastudies/index.cfm?gene=MTHFD1L

Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities

25 May 2020

RELN

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=5649

http://www.genome.gov/gwastudies/index.cfm?gene=RELN

Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study

25 May 2020

PCDH11X

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=27328

http://www.genome.gov/gwastudies/index.cfm?gene=PCDH11X

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

25 May 2020

GAB2

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10652&ncbiId=9846

http://www.genome.gov/gwastudies/index.cfm?gene=GAB2

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers

25 May 2020

APP

4 references

The 717Val----Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups

Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Open Targets Platform

24 August 2023

https://platform.opentargets.org/evidence/ENSG00000142192/MONDO_0004975

based on heuristic

inferred from an Open Targets association score over 0.7

PLD3

1 reference

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

on focus list of Wikimedia project

Wikipedia:List of articles all languages should have

0 references

WikiProject Zika Corpus

0 references

WikiProject Medicine

0 references

Wikipedia:Vital articles/Level/4

point in time

31 October 2022

0 references

schematic

Alzheimer's disease brain comparison.jpg
3,984 × 1,800; 7.46 MB

English

0 references

ChAlzheimera-obraz-mózguPL.jpg
1,920 × 867; 548 KB

Polish

0 references

Alzheimer's disease brain comparison-ar.jpg
3,984 × 1,800; 7.98 MB

Arabic

0 references

Alzheimer's disease brain comparison-zh.jpg
3,984 × 1,800; 1.46 MB

Chinese

0 references

Cerebro corte frontal Alzheimer.jpg
3,984 × 1,800; 818 KB

Prevalence and incidence of Alzheimer's disease in Europe: A meta-analysis

0 references

0.0505

1 reference

social media followers

12,071

24 May 2023

0 references

331.0

2 references

15 May 2019

3 July 2018

290.1

1 reference

3 July 2018

P70

1 reference

Spanish Wikipedia

NCI Thesaurus ID

C38778

mapping relation type

close match

1 reference

3 July 2018

C34524

mapping relation type

close match

1 reference

3 July 2018

http://purl.obolibrary.org/obo/DOID_10652

C2866

1 reference

15 May 2019

1 reference

30 November 2020

http://identifiers.org/doid/DOID:10652

1 reference

Identifiers.org

https://registry.identifiers.org/registry/doid

different from

Asperger syndrome

0 references

Commons category

Alzheimer's disease

0 references

topic's main category

Category:Alzheimer's disease

0 references

Identifiers

National Library of Spain ID

XX531806

Enfermedad de Alzheimer

2 references

Nuovo soggettario

https://thes.bncf.firenze.sbn.it/termine.php?id=27700

15 June 2021

Spain open data portal

title

Registros de autoridad de "Materia" de la Biblioteca Nacional de España (Spanish)

https://www.bne.es/media/datosgob/catalogo-autoridades/materia/materia-UTF8.zip

Bibliothèque nationale de France ID

21 July 2023

11964909n

0 references

GND ID

4112510-1

1 reference

National Library of Israel

1 reference

Library of Congress authority ID

sh85004080

1 reference

Japanese Wikipedia

NDL Authority ID

00576638

1 reference

Alzheimerova choroba

0 references

0 references

0 references

mapping relation type

exact match

Alzheimer Disease

1 reference

3 July 2018

0 references

0 references

0 references

1 reference

PatientsLikeMe condition ID

0 references

0 references

alzheimers-and-dementia

0 references

Analysis & Policy Observatory term ID

21556

0 references

Australian Educational Vocabulary ID

0 references

0 references

1556c286-37f3-4949-abf4-715baef41995

1 reference

1 reference

Cultureel Woordenboek ID

levenswetenschappen-en-geneeskunde/alzheimer

0 references

0 references

1 reference

30 November 2020

1 reference

eMedicine ID

1134817

1 reference

Encyclopædia Britannica Online ID

science/Alzheimer-disease

Encyclopædia Universalis ID

Alzheimer disease

0 references

maladie-d-alzheimer

0 references

Encyclopedia of China (Third Edition) ID

133686

France 24 topic ID (French)

阿尔茨海默病

0 references

FactGrid item ID

Q892212

0 references

0 references

1 reference

28 October 2013

1 reference

15 May 2019

1 reference

Genetics Home Reference Conditions ID

alzheimer-disease

0 references

Gran Enciclopèdia Catalana ID

malaltia-dalzheimer

0 references

Gran Enciclopèdia Catalana ID (former scheme)

0003254

0 references

Great Russian Encyclopedia Online ID (old version)

1816662

Human Phenotype Ontology ID

АЛЬЦГЕЙМЕРА БОЛЕЗНЬ

0 references

0 references

2 references

15 May 2019

3 July 2018

2 references

15 May 2019

3 July 2018

ICD-11 ID (Foundation)

1611724421

0 references

ICD-11 ID (MMS)

8A20

medicina/ALTSGEMERA_BOLEZN.html

Alzheimer disease

0 references

1 reference

9 July 2020

0 references

0 references

Le Figaro tag ID

maladie-d'Alzheimer

0 references

Microsoft Academic ID

0 references

0 references

0 references

1 reference

https://www.nhs.uk/conditions/alzheimers-disease/

OmegaWiki Defined Meaning

802769

0 references

OMIM ID

104300

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

26 January 2022

archive URL

https://web.archive.org/web/20220125070108/https://docs.openalex.org/download-snapshot/snapshot-data-format

25 January 2022

1 reference

http://www.patient.co.uk/patientplus/a.htm

Quora topic ID

Alzheimers-Disease

0 references

ScienceDirect topic ID

pharmacology-toxicology-and-pharmaceutical-science/alzheimer-disease

0 references

nursing-and-health-professions/alzheimer-disease

0 references

engineering/alzheimers-disease

0 references

psychology/alzheimers-disease

0 references

neuroscience/alzheimers-disease

0 references

Alzheimers

30 September 2009

TheFreeDictionary medical term ID

English

point in time

24 May 2023

0 references

Alzheimer's disease

0 references

UK Archival Thesaurus ID

f2/mt285/649/3032/4093/7842/7776/7534

UK Parliament thesaurus ID

Alzheimer's disease

0 references

8323