RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation (Q36499078)

14 August 2017

RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation (English)

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14 August 2017

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Wei Zou

8

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Deborah V Novack

object named as

Deborah Veis Novack

11

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author name string

Sergio Vaira

1

1 reference

14 August 2017

Trevor Johnson

2

1 reference

14 August 2017

Angela C Hirbe

3

1 reference

14 August 2017

Muhammad Alhawagri

4

1 reference

14 August 2017

Imani Anwisye

5

1 reference

14 August 2017

Benedicte Sammut

6

1 reference

14 August 2017

Julie O'Neal

7

1 reference

14 August 2017

Katherine N Weilbaecher

9

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14 August 2017

Roberta Faccio

10

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14 August 2017

language of work or name

English

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publication date

5 March 2008

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14 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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14 August 2017

105

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14 August 2017

10

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14 August 2017

3897-3902

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X-ray Structure of a NF-κB p50/RelB/DNA Complex Reveals Assembly of Multiple Dimers on Tandem κB Sites

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

NF-(kappa)B-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Osteoclast differentiation is impaired in the absence of inhibitor of kappa B kinase alpha

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

30 September 2017

Signaling to NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Divergent C-terminal transactivation domains of Rel/NF-kappa B proteins are critical determinants of their oncogenic potential in lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Platelet and osteoclast β 3 integrins are critical for bone metastasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Genetic analysis of NF- B/Rel transcription factors defines functional specificities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

IL-4 abrogates osteoclastogenesis through STAT6-dependent inhibition of NF-kappaB

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Receptor activator of nuclear factor-kappa b ligand activates nuclear factor-kappa b in osteoclast precursors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Requirement for NF-kappaB in osteoclast and B-cell development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Both N- and C-terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

NF-kappa B: a lesson in family values

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Modulation of NF-kappaB activity by exchange of dimers.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

RelB reduces thymocyte apoptosis and regulates terminal thymocyte maturation.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268780

Marrow Stromal Cells and Osteoclast Precursors Differentially Contribute to TNF- -Induced Osteoclastogenesis In Vivo

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0708576105

The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Abnormal immune function of hemopoietic cells from alymphoplasia (aly) mice, a natural strain with mutant NF-kappa B-inducing kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

RelB regulates human dendritic cell subset development by promoting monocyte intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Real-time imaging of ligand-induced IKK activation in intact cells and in living mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Dominant-negative IkappaB facilitates apoptosis of osteoclasts by tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Regulation of Developing B Cell Survival by RelA-Containing NF-κB Complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Cutting edge: NF-kappa B2 is a negative regulator of dendritic cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18322009

12 December 2020

Identifiers

DOI

10.1073/PNAS.0708576105

1 reference

14 August 2017

0 references

1 reference

14 August 2017

PubMed publication ID

18322009

1 reference