Hypoxia-inducible factors, stem cells, and cancer (Q34625782)

3 August 2017

1 reference

title

Hypoxia-inducible factors, stem cells, and cancer (English)

1 reference

3 August 2017

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Brian Keith

1

1 reference

3 August 2017

M Celeste Simon

series ordinal

2

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3 August 2017

language of work or name

English

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publication date

1 May 2007

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3 August 2017

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3 August 2017

volume

129

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3 August 2017

issue

3

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3 August 2017

page(s)

465-472

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HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

3 August 2017

cites work

1 reference

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Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

7 July 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

7 July 2018

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Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

7 July 2018

1 reference

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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

7 July 2018

1 reference

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Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.

7 July 2018

1 reference

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Asymmetric and symmetric stem-cell divisions in development and cancer

7 July 2018

1 reference

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Hypoxia signalling in cancer and approaches to enforce tumour regression

7 July 2018

1 reference

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7 July 2018

Brain tumour stem cells

1 reference

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Control of developmental regulators by Polycomb in human embryonic stem cells

7 July 2018

1 reference

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Multiple functions of Notch signaling in self-renewing organs and cancer.

7 July 2018

1 reference

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The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation

7 July 2018

1 reference

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Hypoxia requires notch signaling to maintain the undifferentiated cell state

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia-induced dedifferentiation of tumor cells--a mechanism behind heterogeneity and aggressiveness of solid tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Toward an understanding of the physiological function of Mammalian stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Dynamics of chronic myeloid leukaemia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

T cell acute lymphoblastic leukemia/lymphoma: a human cancer commonly associated with aberrant NOTCH1 signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

The stem cell niche: theme and variations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Oct4 is required for primordial germ cell survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Multiple niches for Notch in cancer: context is everything

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Targeting HIF-1 for cancer therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Expansion of human SCID-repopulating cells under hypoxic conditions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Stem cells, cancer, and cancer stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia-inducible factor and the development of stem cells of the cardiovascular system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Angiogenesis in cancer and other diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

The adult Drosophila posterior midgut is maintained by pluripotent stem cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Leukaemia stem cells and the evolution of cancer-stem-cell research.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Two HIFs may be better than one.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Regulation of human placental development by oxygen tension

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150586

Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17482542

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Oct-3/4 is a dose-dependent oncogenic fate determinant

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17482542

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of hypoxia in the maintenance of hematopoietic stem cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17482542

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2007.04.019

1 reference

3 August 2017

1 reference

3 August 2017

1 reference