The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. (Q34097297)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705491%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity (English)

1 reference

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9 February 2020

1

1 reference

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9 February 2020

Emre Turer

2

1 reference

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author name string

Chih L Liu

3

1 reference

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9 February 2020

Rommel Advincula

4

1 reference

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9 February 2020

Patrizia Scapini

5

1 reference

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9 February 2020

Lesley Rhee

6

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9 February 2020

Julio Barrera

7

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9 February 2020

Clifford A Lowell

8

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9 February 2020

Paul J Utz

9

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9 February 2020

Barbara A Malynn

10

1 reference

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9 February 2020

Averil Ma

11

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

12 August 2010

1 reference

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9 February 2020

1 reference

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volume

33

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issue

2

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page(s)

181-191

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Checkpoints in lymphocyte development and autoimmune disease

9 February 2020

cites work

1 reference

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A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

5 July 2018

1 reference

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The role of ubiquitin in NF-kappaB regulatory pathways.

5 July 2018

1 reference

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Molecular mechanism and function of CD40/CD40L engagement in the immune system.

5 July 2018

1 reference

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Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

5 July 2018

1 reference

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Frequent inactivation of A20 in B-cell lymphomas

5 July 2018

1 reference

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TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

5 July 2018

1 reference

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The NF-{kappa}B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas.

5 July 2018

1 reference

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Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

5 July 2018

1 reference

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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

5 July 2018

1 reference

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Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis

5 July 2018

1 reference

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Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis

5 July 2018

1 reference

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The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

5 July 2018

1 reference

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Shared principles in NF-kappaB signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Sites and stages of autoreactive B cell activation and regulation.

5 July 2018

1 reference

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IgM antibodies against dsDNA in SLE.

5 July 2018

1 reference

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Germinal centres: role in B-cell physiology and malignancy

5 July 2018

1 reference

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Regulation of autoreactive antibodies

5 July 2018

1 reference

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Vagaries of conditional gene targeting

5 July 2018

1 reference

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Control of B lymphocyte apoptosis by the transcription factor NF-kappaB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease.

5 July 2018

1 reference

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TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE.

5 July 2018

1 reference

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Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

5 July 2018

1 reference

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Balancing diversity and tolerance: lessons from patients with systemic lupus erythematosus

5 July 2018

1 reference

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Control of lymphocyte development by nuclear factor-kappaB.

5 July 2018

1 reference

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Fas-induced apoptosis in B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis

5 July 2018

1 reference

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Significance analysis of microarrays applied to the ionizing radiation response

5 July 2018

1 reference

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

B lymphocyte-specific, Cre-mediated mutagenesis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

NF-kappa B is required for surface Ig-induced Fas resistance in B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Autoantigen microarrays for multiplex characterization of autoantibody responses

28 October 2018

1 reference

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Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice

28 October 2018

1 reference

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Expression and function of Fas antigen on activated murine B cells.

28 October 2018

1 reference

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CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2931361

Requirement of Fas expression in B cells for tolerance induction

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20705491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evolution of autoantibody responses via somatic hypermutation outside of germinal centers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20705491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20705491

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.IMMUNI.2010.07.017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705491%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20705491%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

20705491

1 reference