Cyclin-dependent kinase inhibitor p21 modulates the DNA primer-template recognition complex (Q33774973)

29 July 2017

title

Cyclin-dependent kinase inhibitor p21 modulates the DNA primer-template recognition complex (English)

1 reference

29 July 2017

S Waga

1

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29 July 2017

B Stillman

series ordinal

2

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29 July 2017

language of work or name

English

0 references

publication date

1 July 1998

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Molecular and Cellular Biology

29 July 2017

published in

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29 July 2017

volume

18

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29 July 2017

issue

7

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29 July 2017

page(s)

4177-4187

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The DNA replication fork in eukaryotic cells.

29 July 2017

cites work

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Reconstitution of recombinant human replication factor C (RFC) and identification of an RFC subcomplex possessing DNA-dependent ATPase activity

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The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

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Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

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Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

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New functional activities for the p21 family of CDK inhibitors

4 July 2018

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Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells

4 July 2018

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p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex

4 July 2018

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Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

4 July 2018

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Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

4 July 2018

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Cyclin-binding motifs are essential for the function of p21CIP1

4 July 2018

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Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast

4 July 2018

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Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

4 July 2018

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Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

4 July 2018

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Determination of the epitope of an inhibitory antibody to proliferating cell nuclear antigen

4 July 2018

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A non-enzymatic p21 protein inhibitor of stress-activated protein kinases

4 July 2018

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Analysis of wild-type and mutant p21WAF-1 gene activities

4 July 2018

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Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction.

4 July 2018

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Differential replication of a single, UV-induced lesion in the leading or lagging strand by a human cell extract: fork uncoupling or gap formation

4 July 2018

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cDNAs encoding the large subunit of human replication factor C

4 July 2018

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WAF1, a potential mediator of p53 tumor suppression

4 July 2018

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Recombinant replication protein A: expression, complex formation, and functional characterization

4 July 2018

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Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis

4 July 2018

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Induction of WAF1/CIP1 by a p53-independent pathway

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

p21-containing cyclin kinases exist in both active and inactive states

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

4 July 2018

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Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

4 July 2018

1 reference

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Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

4 July 2018

1 reference

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Increase in expression level of p21sdi1/cip1/waf1 with increasing division age in both normal and SV40-transformed human fibroblasts

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Inhibitors of mammalian G1 cyclin-dependent kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Structure-function relationship of the eukaryotic DNA replication factor, proliferating cell nuclear antigen

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Inhibition of cyclin-dependent kinases by p21

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109002

Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21.

4 July 2018

1 reference

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Radiation-induced cell cycle arrest compromised by p21 deficiency

4 July 2018

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Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition

4 July 2018

1 reference

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An auxiliary protein for DNA polymerase-delta from fetal calf thymus

4 July 2018

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The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta

4 July 2018

1 reference

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Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA.

4 July 2018

1 reference

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Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein

4 July 2018

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Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta

4 July 2018

1 reference

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Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during simian virus 40 DNA replication in vitro

4 July 2018

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Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells

4 July 2018

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Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1

4 July 2018

1 reference

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Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.

4 July 2018

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Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form

4 July 2018

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Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis

4 July 2018

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Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins

4 July 2018

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D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

4 July 2018

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Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex

4 July 2018

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Assembly of functional replication factor C expressed using recombinant baculoviruses.

4 July 2018

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p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity.

30 October 2018

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

30 October 2018

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A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

30 October 2018

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Saccharomyces cerevisiae replication factor C. II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerases delta and epsilon

30 October 2018

1 reference

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Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

30 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

The influence of the proliferating cell nuclear antigen-interacting domain of p21(CIP1) on DNA synthesis catalyzed by the human and Saccharomyces cerevisiae polymerase delta holoenzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

Mechanism of bacteriophage T4 DNA holoenzyme assembly: the 44/62 protein acts as a molecular motor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9632802

12 December 2020

Identifiers

DOI

10.1128/MCB.18.7.4177

1 reference

29 July 2017

1 reference

29 July 2017

1 reference